Hormonal regulation of oligopeptide transporter Pept-1 in a human intestinal cell line

American Journal of Physiology - Cell Physiology

Volumn 276, Issue 4 45-4, 1999, Pages

  Thamotharan, Manikkavasagar ^a   Bawani, Shahab Zare ^a   Zhou, Xiaodong ^a   Adibi, Siamak A ^a,b  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PITTSBURGH   (United States)

Author keywords

Caco 2 cells; Gene expression; Glycylglutamine; Insulin; Microtubules

Indexed keywords

CARRIER PROTEIN; GENISTEIN; GLYCYLGLUTAMINE; INSULIN; INSULIN RECEPTOR; OLIGOPEPTIDE; PROTEIN TYROSINE KINASE INHIBITOR;

AMINO ACID TRANSPORT; APICAL MEMBRANE; ARTICLE; CELL STRAIN CACO 2; CONTROLLED STUDY; GOLGI COMPLEX; HORMONAL REGULATION; HUMAN; HUMAN CELL; INTESTINE CELL; MICHAELIS CONSTANT; MICROTUBULE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN TRANSPORT;

EID: 0032959490     PISSN: 03636143     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpcell.1999.276.4.c821     Document Type: Article

References (8)

1. Achler, C., D. Filmer, C. Merte, and D. Drenckhahn. Role of microtubules in polarized delivery of apical membrane proteins to the brush border of the intestinal epithelium. J. Cell Biol. 109: 179-189, 1989.
2. Adibi, S. A. The oligopeptide transporter (Pept-1) in human intestine: biology and function. Gastroenterology 113: 332-340, 1997.
3. Baron-Delage, S., J. Capeau, V. Barbu, E. Chastre, P. Levy, C. Gespach, and G. Cherqui. Reduced insulin receptor expression and function in human colonic Caco-2 cells by ras and polyoma middle T oncogenes. J. Biol. Chem. 269: 18686-18693, 1994.
4. Chicco, A. G., S. A. Adibi, W.-Q. Liu, S. M. Morris, Jr., and H. S. Paul. Regulation of gene expression of branched-chain keto acid dehydrogenase complex in primary cultured hepatocytes by dexamethasone and a cAMP analog. J. Biol. Chem. 269: 19427-19434, 1994.
5. +/ peptide cotransporters PEPT1 and PEPT2. Biochemistry 36: 452-460, 1997.
6. Gallo-Payet, N., and J. S. Hugon. Insulin receptors in isolated adult mouse intestinal cells: studies in vivo and in organ culture. Endocrinology 114: 1885-1892, 1984.
7. Gingerich, R. L., W. R. Gilbert, P. G. Comens, and J. R. Gavin III. Identification and characterization of insulin receptors in basolateral membranes of dog intestinal mucosa. Diabetes 36: 1124-1129, 1987.
8. Laemmli, U. K. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685, 1970.