Feedback regulation on PTEN/AKT pathway by the ER stress kinase PERK mediated by interaction with the vault complex

Cellular Signalling

Volumn 27, Issue 3, 2015, Pages 436-442

  Zhang, Wei ^a   Neo, Suat Peng ^a   Gunaratne, Jayantha ^a   Poulsen, Anders ^b   Boping, Liu ^b   Ong, Esther Hongqian ^b   Sangthongpitag, Kanda ^b   Pendharkar, Vishal ^b   Hill, Jeffrey ^b   Cohen, Stephen M ^a,c  

^a INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^b Agency for Science   (Singapore)

^c NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

ER stress; MVP; PERK inhibitors; PTEN; Vaults

Indexed keywords

FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, HUMAN; LUNG RESISTANCE PROTEIN; NUCLEAR PROTEIN; PARP4 PROTEIN, HUMAN; PERK KINASE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN KINASE B; PROTEIN KINASE INHIBITOR; PROTEIN KINASE R; PTEN PROTEIN, HUMAN; RIBONUCLEOPROTEIN;

AMINO ACID SUBSTITUTION; ANTAGONISTS AND INHIBITORS; CHEMISTRY; DRUG EFFECTS; ENDOPLASMIC RETICULUM STRESS; GENETICS; HEK293 CELL LINE; HELA CELL LINE; HEPG2 CELL LINE; HUMAN; METABOLISM; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

AMINO ACID SUBSTITUTION; CELL LINE, TUMOR; EIF-2 KINASE; ENDOPLASMIC RETICULUM STRESS; FORKHEAD TRANSCRIPTION FACTORS; HEK293 CELLS; HELA CELLS; HEP G2 CELLS; HUMANS; NUCLEAR PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PROTEIN KINASE INHIBITORS; PROTO-ONCOGENE PROTEINS C-AKT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; VAULT RIBONUCLEOPROTEIN PARTICLES;

EID: 84920068722     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2014.12.010     Document Type: Article

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