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Volumn 5, Issue 23, 2014, Pages 12428-12439

TERT promoter mutations are associated with distant metastases in upper tract urothelial carcinomas and serve as urinary biomarkers detected by a sensitive castPCR

Author keywords

Cancer biomarkers; Promoter mutations; Telomerase; TERT; UTUC

Indexed keywords

BIOLOGICAL MARKER; CYSTEINE; TELOMERASE REVERSE TRANSCRIPTASE; THREONINE; TELOMERASE; TERT PROTEIN, HUMAN; TUMOR MARKER;

EID: 84920046106     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.2660     Document Type: Article
Times cited : (58)

References (32)
  • 1
    • 84858750992 scopus 로고    scopus 로고
    • Regulation of the human catalytic subunit of telomerase (hTERT)
    • Daniel M, Peek GW, Tollefsbol TO. Regulation of the human catalytic subunit of telomerase (hTERT). Gene. 2012; 498:135-146.
    • (2012) Gene , vol.498 , pp. 135-146
    • Daniel, M.1    Peek, G.W.2    Tollefsbol, T.O.3
  • 2
    • 82755192899 scopus 로고    scopus 로고
    • Role of telomeres and telomerase in cancer
    • Shay JW, Wright WE. Role of telomeres and telomerase in cancer. Semin Cancer Biol. 2011; 21:349-353.
    • (2011) Semin Cancer Biol , vol.21 , pp. 349-353
    • Shay, J.W.1    Wright, W.E.2
  • 3
    • 84901987354 scopus 로고    scopus 로고
    • Telomerase as a "stemness" enzyme
    • Kong F, Zheng C, Xu D. Telomerase as a "stemness" enzyme. Sci China Life Sci. 2014; 57:564-570.
    • (2014) Sci China Life Sci , vol.57 , pp. 564-570
    • Kong, F.1    Zheng, C.2    Xu, D.3
  • 7
    • 84891835829 scopus 로고    scopus 로고
    • Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome
    • Allory Y, Beukers W, Sagrera A, Flandez M, Marques M, Marquez M, van der Keur KA, Dyrskjot L, Lurkin I, Vermeij M. Telomerase Reverse Transcriptase Promoter Mutations in Bladder Cancer: High Frequency Across Stages, Detection in Urine, and Lack of Association with Outcome. Eur Urol. 2014; 65:360-366.
    • (2014) Eur Urol , vol.65 , pp. 360-366
    • Allory, Y.1    Beukers, W.2    Sagrera, A.3    Flandez, M.4    Marques, M.5    Marquez, M.6    van der Keur, K.A.7    Dyrskjot, L.8    Lurkin, I.9    Vermeij, M.10
  • 8
    • 84891828969 scopus 로고    scopus 로고
    • Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine
    • Hurst CD, Platt FM, Knowles MA. Comprehensive mutation analysis of the TERT promoter in bladder cancer and detection of mutations in voided urine. Eur Urol. 2014; 65:367-368.
    • (2014) Eur Urol , vol.65 , pp. 367-368
    • Hurst, C.D.1    Platt, F.M.2    Knowles, M.A.3
  • 10
    • 84891833965 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: a genomic and molecular study
    • Wu S, Huang P, Li C, Huang Y, Li X, Wang Y, Chen C, Lv Z, Tang A, Sun X. Telomerase reverse transcriptase gene promoter mutations help discern the origin of urogenital tumors: a genomic and molecular study. Eur Urol. 2014; 65:274-277.
    • (2014) Eur Urol , vol.65 , pp. 274-277
    • Wu, S.1    Huang, P.2    Li, C.3    Huang, Y.4    Li, X.5    Wang, Y.6    Chen, C.7    Lv, Z.8    Tang, A.9    Sun, X.10
  • 11
    • 84877967061 scopus 로고    scopus 로고
    • Highly prevalent TERT promoter mutations in bladder cancer and brain gliobastoma
    • Liu X, Wu G, Hartmann C, Xing M. Highly prevalent TERT promoter mutations in bladder cancer and brain gliobastoma. Cell Cycle. 2013; 12:1637-1638.
    • (2013) Cell Cycle , vol.12 , pp. 1637-1638
    • Liu, X.1    Wu, G.2    Hartmann, C.3    Xing, M.4
  • 16
    • 84919954084 scopus 로고    scopus 로고
    • TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma
    • Xie H, Liu T, Wang N, Björnhagen V, Höög A, Larsson C, Lui WO, Xu D. TERT promoter mutations and gene amplification: Promoting TERT expression in Merkel cell carcinoma. Oncotarget. 2014; 5:10048-10057.
    • (2014) Oncotarget , vol.5 , pp. 10048-10057
    • Xie, H.1    Liu, T.2    Wang, N.3    Björnhagen, V.4    Höög, A.5    Larsson, C.6    Lui, W.O.7    Xu, D.8
  • 17
    • 85028141478 scopus 로고    scopus 로고
    • The age-and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas
    • Liu T, Wang N, Cao J, Dinets A, Sofiadis A, Zedenius J, Larsson C, Xu D. The age-and shorter telomere-dependent TERT promoter mutation in follicular thyroid cell-derived carcinomas. Oncogene. 2014; 33:4978-4984.
    • (2014) Oncogene , vol.33 , pp. 4978-4984
    • Liu, T.1    Wang, N.2    Cao, J.3    Dinets, A.4    Sofiadis, A.5    Zedenius, J.6    Larsson, C.7    Xu, D.8
  • 18
    • 84908556575 scopus 로고    scopus 로고
    • TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA
    • Wang N, Liu T, Sofiadis A, Juhlin CC, Zedenius J, Hoog A, Larsson C, Xu D. TERT promoter mutation as an early genetic event activating telomerase in follicular thyroid adenoma (FTA) and atypical FTA. Cancer. 2014; 120:2965-2979.
    • (2014) Cancer , vol.120 , pp. 2965-2979
    • Wang, N.1    Liu, T.2    Sofiadis, A.3    Juhlin, C.C.4    Zedenius, J.5    Hoog, A.6    Larsson, C.7    Xu, D.8
  • 21
    • 0035162550 scopus 로고    scopus 로고
    • Expression of telomerase catalytic subunit (hTERT) mRNA does not predict survival in patients with transitional cell carcinoma of the upper urinary tract
    • Nakanishi K, Hiroi S, Kawai T, Aida S, Kasamatsu H, Aurues T, Ikeda T. Expression of telomerase catalytic subunit (hTERT) mRNA does not predict survival in patients with transitional cell carcinoma of the upper urinary tract. Mod Pathol. 2001; 14:1073-1078.
    • (2001) Mod Pathol , vol.14 , pp. 1073-1078
    • Nakanishi, K.1    Hiroi, S.2    Kawai, T.3    Aida, S.4    Kasamatsu, H.5    Aurues, T.6    Ikeda, T.7
  • 24
    • 85047697807 scopus 로고    scopus 로고
    • TERT regulates cell survival independent of telomerase enzymatic activity
    • Cao Y, Li H, Deb S, Liu JP. TERT regulates cell survival independent of telomerase enzymatic activity. Oncogene. 2002; 21:3130-3138.
    • (2002) Oncogene , vol.21 , pp. 3130-3138
    • Cao, Y.1    Li, H.2    Deb, S.3    Liu, J.P.4
  • 25
    • 46749152214 scopus 로고    scopus 로고
    • Actions of human telomerase beyond telomeres
    • Cong Y, Shay JW. Actions of human telomerase beyond telomeres. Cell Res. 2008; 18:725-732.
    • (2008) Cell Res , vol.18 , pp. 725-732
    • Cong, Y.1    Shay, J.W.2
  • 26
    • 84887041006 scopus 로고    scopus 로고
    • Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NF-kappaBdependent transcription
    • Ding D, Xi P, Zhou J, Wang M, Cong YS. Human telomerase reverse transcriptase regulates MMP expression independently of telomerase activity via NF-kappaBdependent transcription. Faseb J. 2013; 27:4375-4383.
    • (2013) Faseb J , vol.27 , pp. 4375-4383
    • Ding, D.1    Xi, P.2    Zhou, J.3    Wang, M.4    Cong, Y.S.5
  • 28
    • 0038819110 scopus 로고    scopus 로고
    • Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis
    • Luiten RM, Pene J, Yssel H, Spits H. Ectopic hTERT expression extends the life span of human CD4+ helper and regulatory T-cell clones and confers resistance to oxidative stress-induced apoptosis. Blood. 2003; 101:4512-4519.
    • (2003) Blood , vol.101 , pp. 4512-4519
    • Luiten, R.M.1    Pene, J.2    Yssel, H.3    Spits, H.4
  • 29
    • 84911477017 scopus 로고    scopus 로고
    • Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress
    • Saretzki G. Extra-telomeric Functions of Human Telomerase: Cancer, Mitochondria and Oxidative Stress. Curr Pharm Des. 2014; DOI: 10.2174/1381612820666140630095606.
    • (2014) Curr Pharm Des
    • Saretzki, G.1
  • 31
    • 84883743387 scopus 로고    scopus 로고
    • Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells
    • Liu Z, Li Q, Li K, Chen L, Li W, Hou M, Liu T, Yang J, Lindvall C, Bjorkholm M, Jia J, Xu D. Telomerase reverse transcriptase promotes epithelial-mesenchymal transition and stem cell-like traits in cancer cells. Oncogene. 2013; 32:4203-4213.
    • (2013) Oncogene , vol.32 , pp. 4203-4213
    • Liu, Z.1    Li, Q.2    Li, K.3    Chen, L.4    Li, W.5    Hou, M.6    Liu, T.7    Yang, J.8    Lindvall, C.9    Bjorkholm, M.10    Jia, J.11    Xu, D.12
  • 32
    • 1242292961 scopus 로고    scopus 로고
    • Handling and pathology reporting of specimens with carcinoma of the urinary bladder, ureter, and renal pelvis
    • Lopez-Beltran A, Bassi P, Pavone-Macaluso M and Montironi R. Handling and pathology reporting of specimens with carcinoma of the urinary bladder, ureter, and renal pelvis. Eur Urol. 2004; 45:257-266.
    • (2004) Eur Urol , vol.45 , pp. 257-266
    • Lopez-Beltran, A.1    Bassi, P.2    Pavone-Macaluso, M.3    Montironi, R.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.