-
2
-
-
77953930730
-
Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR
-
Maemondo M, Inoue A, Kobayashi K, Sugawara S, Oizumi S, Isobe H, Gemma A, Harada M, Yoshizawa H, Kinoshita I, Fujita Y, Okinaga S, Hirano H, Yoshimori K, Harada T, Ogura T, et al. Gefitinib or chemotherapy for non-small-cell lung cancer with mutated EGFR. The New England journal of medicine. 2010; 362:2380-2388.
-
(2010)
The New England journal of medicine
, vol.362
, pp. 2380-2388
-
-
Maemondo, M.1
Inoue, A.2
Kobayashi, K.3
Sugawara, S.4
Oizumi, S.5
Isobe, H.6
Gemma, A.7
Harada, M.8
Yoshizawa, H.9
Kinoshita, I.10
Fujita, Y.11
Okinaga, S.12
Hirano, H.13
Yoshimori, K.14
Harada, T.15
Ogura, T.16
-
3
-
-
70349336416
-
Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK
-
Shaw AT, Yeap BY, Mino-Kenudson M, Digumarthy SR, Costa DB, Heist RS, Solomon B, Stubbs H, Admane S, McDermott U, Settleman J, Kobayashi S, Mark EJ, Rodig SJ, Chirieac LR, Kwak EL, et al. Clinical features and outcome of patients with non-small-cell lung cancer who harbor EML4-ALK. Journal of clinical oncology: official journal of the American Society of Clinical Oncology. 2009; 27:4247-4253.
-
(2009)
Journal of clinical oncology: official journal of the American Society of Clinical Oncology
, vol.27
, pp. 4247-4253
-
-
Shaw, A.T.1
Yeap, B.Y.2
Mino-Kenudson, M.3
Digumarthy, S.R.4
Costa, D.B.5
Heist, R.S.6
Solomon, B.7
Stubbs, H.8
Admane, S.9
McDermott, U.10
Settleman, J.11
Kobayashi, S.12
Mark, E.J.13
Rodig, S.J.14
Chirieac, L.R.15
Kwak, E.L.16
-
5
-
-
79251490374
-
New driver mutations in non-small-cell lung cancer
-
Pao W, Girard N. New driver mutations in non-small-cell lung cancer. The lancet oncology. 2011; 12:175-180.
-
(2011)
The lancet oncology
, vol.12
, pp. 175-180
-
-
Pao, W.1
Girard, N.2
-
6
-
-
84899957391
-
Beyond EGFR TKI in EGFR-mutant Non-Small Cell Lung Cancer patients: Main challenges still to be overcome
-
Remon J, Moran T, Reguart N, Majem M, Carcereny E, Lianes P. Beyond EGFR TKI in EGFR-mutant Non-Small Cell Lung Cancer patients: Main challenges still to be overcome. Cancer treatment reviews. 2014; 40:723-729.
-
(2014)
Cancer treatment reviews
, vol.40
, pp. 723-729
-
-
Remon, J.1
Moran, T.2
Reguart, N.3
Majem, M.4
Carcereny, E.5
Lianes, P.6
-
7
-
-
84879071011
-
Crizotinib versus chemotherapy in advanced ALK-positive lung cancer
-
Shaw AT, Kim DW, Nakagawa K, Seto T, Crino L, Ahn MJ, De Pas T, Besse B, Solomon BJ, Blackhall F, Wu YL, Thomas M, O'Byrne KJ, Moro-Sibilot D, Camidge DR, Mok T, et al. Crizotinib versus chemotherapy in advanced ALK-positive lung cancer. The New England journal of medicine. 2013; 368:2385-2394.
-
(2013)
The New England journal of medicine
, vol.368
, pp. 2385-2394
-
-
Shaw, A.T.1
Kim, D.W.2
Nakagawa, K.3
Seto, T.4
Crino, L.5
Ahn, M.J.6
De Pas, T.7
Besse, B.8
Solomon, B.J.9
Blackhall, F.10
Wu, Y.L.11
Thomas, M.12
O'Byrne, K.J.13
Moro-Sibilot, D.14
Camidge, D.R.15
Mok, T.16
-
8
-
-
84876976986
-
Novel anticancer therapeutics targeting telomerase
-
Ruden M, Puri N. Novel anticancer therapeutics targeting telomerase. Cancer treatment reviews. 2013; 39:444-456.
-
(2013)
Cancer treatment reviews
, vol.39
, pp. 444-456
-
-
Ruden, M.1
Puri, N.2
-
9
-
-
39449092745
-
Targeting telomerase for cancer therapeutics
-
Shay JW, Keith WN. Targeting telomerase for cancer therapeutics. British journal of cancer. 2008; 98:677-683.
-
(2008)
British journal of cancer
, vol.98
, pp. 677-683
-
-
Shay, J.W.1
Keith, W.N.2
-
12
-
-
25444522262
-
Telomerase and Cancer: Kirk A. Landon-AACR prize for basic cancer research lecture
-
Blackburn EH. Telomerase and Cancer: Kirk A. Landon-AACR prize for basic cancer research lecture. Molecular cancer research: MCR. 2005; 3:477-482.
-
(2005)
Molecular cancer research: MCR
, vol.3
, pp. 477-482
-
-
Blackburn, E.H.1
-
13
-
-
33745679352
-
Telomerase therapeutics for cancer: challenges and new directions
-
Shay JW, Wright WE. Telomerase therapeutics for cancer: challenges and new directions. Nature reviews Drug discovery. 2006; 5:577-584.
-
(2006)
Nature reviews Drug discovery
, vol.5
, pp. 577-584
-
-
Shay, J.W.1
Wright, W.E.2
-
14
-
-
49749139661
-
Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers
-
Kyo S, Takakura M, Fujiwara T, Inoue M. Understanding and exploiting hTERT promoter regulation for diagnosis and treatment of human cancers. Cancer science. 2008; 99:1528-1538.
-
(2008)
Cancer science
, vol.99
, pp. 1528-1538
-
-
Kyo, S.1
Takakura, M.2
Fujiwara, T.3
Inoue, M.4
-
15
-
-
79957507517
-
ATRA activates and PDGF-BB represses the SM22alpha promoter through KLF4 binding to, or dissociating from, its cis-DNA elements
-
Yu K, Zheng B, Han M, Wen JK. ATRA activates and PDGF-BB represses the SM22alpha promoter through KLF4 binding to, or dissociating from, its cis-DNA elements. Cardiovascular research. 2011; 90:464-474.
-
(2011)
Cardiovascular research
, vol.90
, pp. 464-474
-
-
Yu, K.1
Zheng, B.2
Han, M.3
Wen, J.K.4
-
16
-
-
84872271398
-
Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease
-
Lu B, Lee J, Nie X, Li M, Morozov YI, Venkatesh S, Bogenhagen DF, Temiakov D, Suzuki CK. Phosphorylation of human TFAM in mitochondria impairs DNA binding and promotes degradation by the AAA+ Lon protease. Molecular cell. 2013; 49:121-132.
-
(2013)
Molecular cell
, vol.49
, pp. 121-132
-
-
Lu, B.1
Lee, J.2
Nie, X.3
Li, M.4
Morozov, Y.I.5
Venkatesh, S.6
Bogenhagen, D.F.7
Temiakov, D.8
Suzuki, C.K.9
-
17
-
-
84884139186
-
Activation of the transcriptional function of the NF-kappaB protein c-Rel by O-GlcNAc glycosylation
-
Ramakrishnan P, Clark PM, Mason DE, Peters EC, Hsieh-Wilson LC, Baltimore D. Activation of the transcriptional function of the NF-kappaB protein c-Rel by O-GlcNAc glycosylation. Science signaling. 2013; 6:ra75.
-
(2013)
Science signaling
, vol.6
-
-
Ramakrishnan, P.1
Clark, P.M.2
Mason, D.E.3
Peters, E.C.4
Hsieh-Wilson, L.C.5
Baltimore, D.6
-
19
-
-
84880278604
-
Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairment
-
Powers NR, Eicher JD, Butter F, Kong Y, Miller LL, Ring SM, Mann M, Gruen JR. Alleles of a polymorphic ETV6 binding site in DCDC2 confer risk of reading and language impairment. American journal of human genetics. 2013; 93:19-28.
-
(2013)
American journal of human genetics
, vol.93
, pp. 19-28
-
-
Powers, N.R.1
Eicher, J.D.2
Butter, F.3
Kong, Y.4
Miller, L.L.5
Ring, S.M.6
Mann, M.7
Gruen, J.R.8
-
21
-
-
84875419951
-
Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression
-
Picard C, Pellicelli M, Taheri M, Lavoie JF, Doucet R, Wang D, Bernard L, Bouhanik S, Lavigne P, Moreau A. Nuclear accumulation of prohibitin 1 in osteoarthritic chondrocytes down-regulates PITX1 expression. Arthritis and rheumatism. 2013; 65:993-1003.
-
(2013)
Arthritis and rheumatism
, vol.65
, pp. 993-1003
-
-
Picard, C.1
Pellicelli, M.2
Taheri, M.3
Lavoie, J.F.4
Doucet, R.5
Wang, D.6
Bernard, L.7
Bouhanik, S.8
Lavigne, P.9
Moreau, A.10
-
22
-
-
0346996870
-
Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation
-
Deng WG, Wu KK. Regulation of inducible nitric oxide synthase expression by p300 and p50 acetylation. J Immunol. 2003; 171:6581-6588.
-
(2003)
J Immunol
, vol.171
, pp. 6581-6588
-
-
Deng, W.G.1
Wu, K.K.2
-
23
-
-
33745932460
-
Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding
-
Deng WG, Tang ST, Tseng HP, Wu KK. Melatonin suppresses macrophage cyclooxygenase-2 and inducible nitric oxide synthase expression by inhibiting p52 acetylation and binding. Blood. 2006; 108:518-524.
-
(2006)
Blood
, vol.108
, pp. 518-524
-
-
Deng, W.G.1
Tang, S.T.2
Tseng, H.P.3
Wu, K.K.4
-
24
-
-
1542343955
-
Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators
-
Deng WG, Zhu Y, Wu KK. Role of p300 and PCAF in regulating cyclooxygenase-2 promoter activation by inflammatory mediators. Blood. 2004; 103:2135-2142.
-
(2004)
Blood
, vol.103
, pp. 2135-2142
-
-
Deng, W.G.1
Zhu, Y.2
Wu, K.K.3
-
25
-
-
48349144820
-
Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development
-
Bonnefont J, Nikolaev SI, Perrier AL, Guo S, Cartier L, Sorce S, Laforge T, Aubry L, Khaitovich P, Peschanski M, Antonarakis SE, Krause KH. Evolutionary forces shape the human RFPL1,2,3 genes toward a role in neocortex development. American journal of human genetics. 2008; 83:208-218.
-
(2008)
American journal of human genetics
, vol.83
, pp. 208-218
-
-
Bonnefont, J.1
Nikolaev, S.I.2
Perrier, A.L.3
Guo, S.4
Cartier, L.5
Sorce, S.6
Laforge, T.7
Aubry, L.8
Khaitovich, P.9
Peschanski, M.10
Antonarakis, S.E.11
Krause, K.H.12
-
26
-
-
84862686733
-
Transcriptome analysis during human trophectoderm specification suggests new roles of metabolic and epigenetic genes
-
Assou S, Boumela I, Haouzi D, Monzo C, Dechaud H, Kadoch IJ, Hamamah S. Transcriptome analysis during human trophectoderm specification suggests new roles of metabolic and epigenetic genes. PloS one. 2012; 7:e39306.
-
(2012)
PloS one
, vol.7
-
-
Assou, S.1
Boumela, I.2
Haouzi, D.3
Monzo, C.4
Dechaud, H.5
Kadoch, I.J.6
Hamamah, S.7
-
27
-
-
78651339945
-
Primate-specific RFPL1 gene controls cell-cycle progression through cyclin B1/Cdc2 degradation
-
Bonnefont J, Laforge T, Plastre O, Beck B, Sorce S, Dehay C, Krause KH. Primate-specific RFPL1 gene controls cell-cycle progression through cyclin B1/Cdc2 degradation. Cell death and differentiation. 2011; 18:293-303.
-
(2011)
Cell death and differentiation
, vol.18
, pp. 293-303
-
-
Bonnefont, J.1
Laforge, T.2
Plastre, O.3
Beck, B.4
Sorce, S.5
Dehay, C.6
Krause, K.H.7
-
28
-
-
34548853126
-
Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancerbinding protein-2beta in human lung cancer cells
-
Deng WG, Jayachandran G, Wu G, Xu K, Roth JA, Ji L. Tumor-specific activation of human telomerase reverses transcriptase promoter activity by activating enhancerbinding protein-2beta in human lung cancer cells. The Journal of biological chemistry. 2007; 282:26460-26470.
-
(2007)
The Journal of biological chemistry
, vol.282
, pp. 26460-26470
-
-
Deng, W.G.1
Jayachandran, G.2
Wu, G.3
Xu, K.4
Roth, J.A.5
Ji, L.6
-
29
-
-
80052824551
-
Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer
-
Aragaki M, Takahashi K, Akiyama H, Tsuchiya E, Kondo S, Nakamura Y, Daigo Y. Characterization of a cleavage stimulation factor, 3' pre-RNA, subunit 2, 64 kDa (CSTF2) as a therapeutic target for lung cancer. Clinical cancer research: an official journal of the American Association for Cancer Research. 2011; 17:5889-5900.
-
(2011)
Clinical cancer research: an official journal of the American Association for Cancer Research
, vol.17
, pp. 5889-5900
-
-
Aragaki, M.1
Takahashi, K.2
Akiyama, H.3
Tsuchiya, E.4
Kondo, S.5
Nakamura, Y.6
Daigo, Y.7
-
30
-
-
39749134771
-
From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma
-
Daigo Y, Nakamura Y. From cancer genomics to thoracic oncology: discovery of new biomarkers and therapeutic targets for lung and esophageal carcinoma. General thoracic and cardiovascular surgery. 2008; 56:43-53.
-
(2008)
General thoracic and cardiovascular surgery
, vol.56
, pp. 43-53
-
-
Daigo, Y.1
Nakamura, Y.2
-
31
-
-
80052786965
-
Activating enhancer-binding protein-2beta nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection
-
Kim MP, Chen Y, Bekele BN, Lopez A, Khanna A, Chen JQ, Spitz MR, Behrens C, Solis L, Wismach M, Ji L, Wistuba II, Roth JA, Katz RL. Activating enhancer-binding protein-2beta nucleolar localization predicts poor survival after stage I non-small cell lung cancer resection. The Annals of thoracic surgery. 2011; 92:1044-1050.
-
(2011)
The Annals of thoracic surgery
, vol.92
, pp. 1044-1050
-
-
Kim, M.P.1
Chen, Y.2
Bekele, B.N.3
Lopez, A.4
Khanna, A.5
Chen, J.Q.6
Spitz, M.R.7
Behrens, C.8
Solis, L.9
Wismach, M.10
Ji, L.11
Wistuba, I.I.12
Roth, J.A.13
Katz, R.L.14
-
32
-
-
66949167418
-
Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics
-
Grass B, Wachtel M, Behnke S, Leuschner I, Niggli FK, Schafer BW. Immunohistochemical detection of EGFR, fibrillin-2, P-cadherin and AP2beta as biomarkers for rhabdomyosarcoma diagnostics. Histopathology. 2009; 54:873-879.
-
(2009)
Histopathology
, vol.54
, pp. 873-879
-
-
Grass, B.1
Wachtel, M.2
Behnke, S.3
Leuschner, I.4
Niggli, F.K.5
Schafer, B.W.6
-
33
-
-
84899491962
-
Myogenin, AP2beta, NOS-1, and HMGA2 Are Surrogate Markers of Fusion Status in Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group
-
Rudzinski ER, Anderson JR, Lyden ER, Bridge JA, Barr FG, Gastier-Foster JM, Bachmeyer K, Skapek SX, Hawkins DS, Teot LA, Parham DM. Myogenin, AP2beta, NOS-1, and HMGA2 Are Surrogate Markers of Fusion Status in Rhabdomyosarcoma: A Report From the Soft Tissue Sarcoma Committee of the Children's Oncology Group. The American journal of surgical pathology. 2014; 38:654-659.
-
(2014)
The American journal of surgical pathology
, vol.38
, pp. 654-659
-
-
Rudzinski, E.R.1
Anderson, J.R.2
Lyden, E.R.3
Bridge, J.A.4
Barr, F.G.5
Gastier-Foster, J.M.6
Bachmeyer, K.7
Skapek, S.X.8
Hawkins, D.S.9
Teot, L.A.10
Parham, D.M.11
-
34
-
-
84904465899
-
FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells
-
Wachtel M, Rakic J, Okoniewski M, Bode P, Niggli F, Schafer BW. FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells. International journal of cancer Journal international du cancer. 2014.
-
(2014)
International journal of cancer Journal international du cancer
-
-
Wachtel, M.1
Rakic, J.2
Okoniewski, M.3
Bode, P.4
Niggli, F.5
Schafer, B.W.6
-
35
-
-
0036716816
-
hTERT expression is a prognostic factor of survival in patients with stage I non-small cell lung cancer
-
Wang L, Soria JC, Kemp BL, Liu DD, Mao L, Khuri FR. hTERT expression is a prognostic factor of survival in patients with stage I non-small cell lung cancer. Clinical cancer research: an official journal of the American Association for Cancer Research. 2002; 8:2883-2889.
-
(2002)
Clinical cancer research: an official journal of the American Association for Cancer Research
, vol.8
, pp. 2883-2889
-
-
Wang, L.1
Soria, J.C.2
Kemp, B.L.3
Liu, D.D.4
Mao, L.5
Khuri, F.R.6
-
36
-
-
11144356221
-
Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours
-
Lantuejoul S, Soria JC, Moro-Sibilot D, Morat L, Veyrenc S, Lorimier P, Brichon PY, Sabatier L, Brambilla C, Brambilla E. Differential expression of telomerase reverse transcriptase (hTERT) in lung tumours. British journal of cancer. 2004; 90:1222-1229.
-
(2004)
British journal of cancer
, vol.90
, pp. 1222-1229
-
-
Lantuejoul, S.1
Soria, J.C.2
Moro-Sibilot, D.3
Morat, L.4
Veyrenc, S.5
Lorimier, P.6
Brichon, P.Y.7
Sabatier, L.8
Brambilla, C.9
Brambilla, E.10
-
37
-
-
33646851581
-
Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer
-
Zhu CQ, Cutz JC, Liu N, Lau D, Shepherd FA, Squire JA, Tsao MS. Amplification of telomerase (hTERT) gene is a poor prognostic marker in non-small-cell lung cancer. British journal of cancer. 2006; 94:1452-1459.
-
(2006)
British journal of cancer
, vol.94
, pp. 1452-1459
-
-
Zhu, C.Q.1
Cutz, J.C.2
Liu, N.3
Lau, D.4
Shepherd, F.A.5
Squire, J.A.6
Tsao, M.S.7
-
38
-
-
2442498638
-
Applying proteomic methodologies to analyze the effect of hexamethylene bisacetamide (HMBA) on proliferation and differentiation of human gastric carcinoma BGC-823 cells
-
Zhang G, Wang G, Wang S, Li Q, Ouyang G, Peng X. Applying proteomic methodologies to analyze the effect of hexamethylene bisacetamide (HMBA) on proliferation and differentiation of human gastric carcinoma BGC-823 cells. The international journal of biochemistry & cell biology. 2004; 36:1613-1623.
-
(2004)
The international journal of biochemistry & cell biology
, vol.36
, pp. 1613-1623
-
-
Zhang, G.1
Wang, G.2
Wang, S.3
Li, Q.4
Ouyang, G.5
Peng, X.6
-
39
-
-
65949113170
-
Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress
-
Kato T, Shimono Y, Hasegawa M, Jijiwa M, Enomoto A, Asai N, Murakumo Y, Takahashi M. Characterization of the HDAC1 complex that regulates the sensitivity of cancer cells to oxidative stress. Cancer research. 2009; 69: 3597-3604.
-
(2009)
Cancer research
, vol.69
, pp. 3597-3604
-
-
Kato, T.1
Shimono, Y.2
Hasegawa, M.3
Jijiwa, M.4
Enomoto, A.5
Asai, N.6
Murakumo, Y.7
Takahashi, M.8
-
40
-
-
84898665608
-
Downregulation of PAX6 by shRNA inhibits proliferation and cell cycle progression of human non-small cell lung cancer cell lines
-
Zhao X, Yue W, Zhang L, Ma L, Jia W, Qian Z, Zhang C, Wang Y. Downregulation of PAX6 by shRNA inhibits proliferation and cell cycle progression of human non-small cell lung cancer cell lines. PloS one. 2014; 9:e85738.
-
(2014)
PloS one
, vol.9
-
-
Zhao, X.1
Yue, W.2
Zhang, L.3
Ma, L.4
Jia, W.5
Qian, Z.6
Zhang, C.7
Wang, Y.8
-
41
-
-
79961175282
-
Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling
-
Xiao X, Shi D, Liu L, Wang J, Xie X, Kang T, Deng W. Quercetin suppresses cyclooxygenase-2 expression and angiogenesis through inactivation of P300 signaling. PloS one. 2011; 6:e22934.
-
(2011)
PloS one
, vol.6
-
-
Xiao, X.1
Shi, D.2
Liu, L.3
Wang, J.4
Xie, X.5
Kang, T.6
Deng, W.7
-
42
-
-
84893832243
-
TFAP2A regulates nasopharyngeal carcinoma growth and survival by targeting HIF-1alpha signaling pathway
-
Shi D, Xie F, Zhang Y, Tian Y, Chen W, Fu L, Wang J, Guo W, Kang T, Huang W, Deng W. TFAP2A regulates nasopharyngeal carcinoma growth and survival by targeting HIF-1alpha signaling pathway. Cancer Prev Res (Phila). 2014; 7:266-277.
-
(2014)
Cancer Prev Res (Phila)
, vol.7
, pp. 266-277
-
-
Shi, D.1
Xie, F.2
Zhang, Y.3
Tian, Y.4
Chen, W.5
Fu, L.6
Wang, J.7
Guo, W.8
Kang, T.9
Huang, W.10
Deng, W.11
|