Fibrinogen nitrotyrosination after ischemic stroke impairs thrombolysis and promotes neuronal death

Biochimica et Biophysica Acta - Molecular Basis of Disease

Volumn 1852, Issue 3, 2015, Pages 421-428

  ILL Raga, Gerard ^a   Palomer, Ernest ^a   Ramos Fernández, Eva ^a   Guix, Francesc X ^a   Bosch Morató, Mònica ^a   Guivernau, Biuse ^a   Tajes, Marta ^a   Valls Comamala, Victòria ^a   Jiménez Conde, Jordi ^b   Ois, Angel ^b   Pérez Asensio, Fernando ^c   Reyes Navarro, Mario ^d   Caballo, Carolina ^e   Gil Gómez, Gabriel ^b   Lopez Vilchez, Irene ^e   Galan, Ana M ^e   Alameda, Francesc ^b   Escolar, Gines ^e   Opazo, Carlos ^d,f   Planas, Anna M ^c   Roquer, Jaume ^b   Valverde, Miguel A ^a   Muñoz, Francisco J ^a   more..

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b HOSPITAL DEL MAR   (Spain)

^c INSTITUT D INVESTIGACIONS BIOMÈDIQUES AUGUST PI I SUNYER IDIBAPS   (Spain)

^d UNIVERSITY OF CONCEPCIÓN   (Chile)

^e UNIVERSITY OF BARCELONA   (Spain)

^f UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Apoptosis; Fibrinogen; Ischemic stroke; Nitric oxide; Peroxynitrite

Indexed keywords

CASPASE 3; FIBRINOGEN; THROMBIN; 3-NITROTYROSINE; CASP3 PROTEIN, HUMAN; CASP3 PROTEIN, RAT; TYROSINE;

ADULT; AGED; ARTICLE; BLOOD CLOT LYSIS; BLOOD CLOTTING; BRAIN; BRAIN ISCHEMIA; CELL SURVIVAL; CHEMICAL MODIFICATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; FEMALE; FIBRINOLYSIS; FLUORESCENCE SPECTROSCOPY; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE TEST; IN VITRO STUDY; IN VIVO STUDY; MALE; MIDDLE AGED; NERVE CELL NECROSIS; NEUROBLASTOMA CELL LINE; NITROTYROSINATION; PATHOPHYSIOLOGY; PLASMA; STROKE PATIENT; THROMBOELASTOGRAPHY; TRANSMISSION ELECTRON MICROSCOPY; ANALOGS AND DERIVATIVES; ANIMAL; APOPTOSIS; CEREBROVASCULAR ACCIDENT; ENZYME ACTIVATION; METABOLISM; NERVE CELL; PATHOLOGY; RAT; SPRAGUE DAWLEY RAT; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; APOPTOSIS; BRAIN; BRAIN ISCHEMIA; CASPASE 3; CELL LINE, TUMOR; ENZYME ACTIVATION; FEMALE; FIBRINOGEN; FIBRINOLYSIS; HUMANS; MALE; MIDDLE AGED; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; STROKE; TYROSINE;

EID: 84919941286     PISSN: 09254439     EISSN: 1879260X     Source Type: Journal    
DOI: 10.1016/j.bbadis.2014.12.007     Document Type: Article

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