The polyketide synthase Pks13 catalyzes a novel mechanism of lipid transfer in mycobacteria

Chemistry and Biology

Volumn 21, Issue 12, 2014, Pages 1660-1669

  Gavalda, Sabine ^a,b   Bardou, Fabienne ^a,b   Laval, Françoise ^a,b   Bon, Cécile ^a,b   Malaga, Wladimir ^a,b   Chalut, Christian ^a,b   Guilhot, Christophe ^a,b   Mourey, Lionel ^a,b   Daffé, Mamadou ^a,b   Quémard, Annaïk ^a,b  

^a INSTITUT DE PHARMACOLOGIE ET DE BIOLOGIE STRUCTURALE   (France)

^b UNIVERSITÉ PAUL SABATIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOSE; GLUCOSE; HYDROXYL GROUP; LIPID TRANSFER PROTEIN; MANNOSE; PKS13 PROTEIN; POLYKETIDE SYNTHASE; POLYOL; THIOL ESTER HYDROLASE; TREHALOSE; UNCLASSIFIED DRUG; ACYLTRANSFERASE; BACTERIAL PROTEIN; MYCOLIC ACID; POLYKETIDE SYNTHASE PKS13, MYCOBACTERIUM TUBERCULOSIS; POLYMER;

ARTICLE; CATALYSIS; CLAISEN CONDENSATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; DECARBOXYLATION; ENZYME SPECIFICITY; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MYCOBACTERIUM; NONHUMAN; PROTEIN HYDROLYSIS; THIN LAYER CHROMATOGRAPHY; WILD TYPE; BIOCATALYSIS; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; PROTEIN TERTIARY STRUCTURE;

CORYNEBACTERINEAE;

ACYLTRANSFERASES; BACTERIAL PROTEINS; BIOCATALYSIS; MODELS, MOLECULAR; MYCOLIC ACIDS; POLYKETIDE SYNTHASES; POLYMERS; PROTEIN STRUCTURE, TERTIARY; SUBSTRATE SPECIFICITY; TREHALOSE;

EID: 84919930327     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.chembiol.2014.10.011     Document Type: Article

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