Sepsis-induced changes in amino acid transporters and leucine signaling via mTOR in skeletal muscle

Amino Acids

Volumn 46, Issue 12, 2014, Pages 2787-2798

  Laufenberg, Lacee J ^a   Pruznak, Anne M ^a   Navaratnarajah, Maithili ^a   Lang, Charles H ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

Author keywords

Amino acid transporters; mTOR; PRAS40; Protein synthesis; Rag GTPases; Ragulator; Sepsis

Indexed keywords

AMINO ACID TRANSPORTER; INITIATION FACTOR 4E BINDING PROTEIN 1; L TYPE AMINO ACID TRANSPORTER 2; LEUCINE; MAMMALIAN TARGET OF RAPAMYCIN; MUSCLE PROTEIN; PROTEIN LAMTOR 1; PROTEIN LAMTOR 2; PROTEIN PRAS40; PROTEIN RAGA; PROTEIN RAGB; PROTEIN RAGC; PROTEIN RAGD; PROTEIN RAPTOR; PROTEIN S6K1; PROTON ASSISTED AMINO ACID TRANSPORTER 2; RHEB PROTEIN; SODIUM COUPLED NEUTRAL AMINO ACID TRANSPORTER 2; UNCLASSIFIED DRUG; TARGET OF RAPAMYCIN KINASE;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GASTROCNEMIUS MUSCLE; MALE; NONHUMAN; PROTEIN BINDING; PROTEIN SYNTHESIS; RAT; SEPSIS; SIGNAL TRANSDUCTION; SKELETAL MUSCLE; ANIMAL; GENETICS; METABOLISM; SPRAGUE DAWLEY RAT;

AMINO ACID TRANSPORT SYSTEMS; ANIMALS; LEUCINE; MALE; MUSCLE, SKELETAL; RATS; RATS, SPRAGUE-DAWLEY; SEPSIS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84919930071     PISSN: 09394451     EISSN: 14382199     Source Type: Journal    
DOI: 10.1007/s00726-014-1836-6     Document Type: Article

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