Folate receptor-targeted dendrimer-methotrexate conjugate for inflammatory arthritis

Journal of Biomedical Nanotechnology

Volumn 11, Issue 8, 2014, Pages 1370-1384

  Qi, Rong ^a,b,c   Majoros, Istvan ^c   Misra, Asish C ^c   Koch, Alisa E ^c   Campbell, Phil ^c   Marotte, Hubert ^c   Bergin, Ingrid L ^c   Cao, Zhengyi ^c   Goonewardena, Sascha ^c   Morry, Jingga ^c   Zhang, Shuai ^c   Beer, Michael ^c   Makidon, Paul ^c   Kotlyar, Alina ^c   Thomas, Thommey P ^c   Baker, James R ^c  

^a PEKING UNIVERSITY HEALTH SCIENCE CENTER   (China)

^b BEIJING UNIVERSITY OF POSTS AND TELECOMMUNICATIONS   (China)

^c UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

Author keywords

Dendrimer Methotrexate conjugates; Folate receptor; Folic acid; Inflammatory arthritis.; Macrophages

Indexed keywords

BINDING ENERGY; CONJUGATED POLYMERS; CONTROLLED DRUG DELIVERY; DENDRIMERS; DISEASES; MACROPHAGES; ORGANIC ACIDS; RAT CONTROL;

ACTIVATED MACROPHAGES; ANTI-INFLAMMATORY DRUGS; ANTI-INFLAMMATORY EFFECTS; DRUG DELIVERY CARRIER; FOLATE RECEPTOR; FOLIC ACIDS; INFLAMMATORY ARTHRITIS; PERITONEAL MACROPHAGE;

FUNCTIONAL POLYMERS;

DENDRIMER; FOLATE RECEPTOR; METHOTREXATE; POLYAMIDOAMINE; FOLIC ACID; NANOCAPSULE; NANOCONJUGATE; PAMAM STARBURST;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; BINDING AFFINITY; CONCENTRATION RESPONSE; CONJUGATE; CONTROLLED STUDY; DRUG BINDING; DRUG EFFICACY; FEMALE; GENE OVEREXPRESSION; HUMAN; HUMAN CELL; IN VITRO STUDY; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; RAT; RHEUMATOID ARTHRITIS; SYNTHESIS; TEMPERATURE DEPENDENCE; ANIMAL; ARTHRITIS; CELL LINE; CHEMISTRY; DIFFUSION; DRUG EFFECTS; LEWIS RAT; METABOLISM; TREATMENT OUTCOME; ULTRASTRUCTURE;

ANIMALS; ARTHRITIS; CELL LINE; DENDRIMERS; DIFFUSION; FEMALE; FOLATE RECEPTORS, GPI-ANCHORED; FOLIC ACID; MACROPHAGES, PERITONEAL; METHOTREXATE; NANOCAPSULES; NANOCONJUGATES; RATS; RATS, INBRED LEW; TREATMENT OUTCOME;

EID: 84919913798     PISSN: 15507033     EISSN: 15507041     Source Type: Journal    
DOI: 10.1166/jbn.2015.2077     Document Type: Article

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