Bifunctional PAMAM dendrimer conjugates of folic acid and methotrexate with defined ratio

Biomacromolecules

Volumn 13, Issue 4, 2012, Pages 982-991

  Zong, Hong ^a   Thomas, Thommey P ^a   Lee, Kyung Hoon ^b   Desai, Ankur M ^a   Li, Ming Hsin ^a   Kotlyar, Alina ^a   Zhang, Yuehua ^a   Leroueil, Pascale R ^a   Gam, Jeremy J ^a   Holl, Mark M Banaszak ^b   Baker, James R ^a  

^a UNIVERSITY OF MICHIGAN HEALTH SYSTEM   (United States)

^b UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBOXYLATION; CYTOTOXICITY; MOLECULES; ORGANIC ACIDS; SYNTHESIS (CHEMICAL);

BI-FUNCTIONAL; CANCER THERAPEUTICS; CHEMOTHERAPEUTIC DRUGS; FOLATE RECEPTOR; FOLIC ACIDS; MULTISTEPS; POLYAMIDOAMINE DENDRIMERS; SYNTHESISED; TARGETING MOLECULES; TUMOUR CELLS;

DENDRIMERS;

CARBOXYLIC ACID DERIVATIVE; DENDRIMER; FOLATE RECEPTOR; FOLIC ACID; METHOTREXATE; MOLECULAR SCAFFOLD; POLYAMIDOAMINE; TRIAZINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ARTICLE; CHEMICAL STRUCTURE; CONJUGATE; CONJUGATION; CONTROLLED STUDY; CYCLOADDITION; CYTOTOXICITY; DRUG SYNTHESIS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; INTERNALIZATION; ISOMER; MACROMOLECULE; MOLECULAR INTERACTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR BINDING; SURFACE PLASMON RESONANCE; TUMOR CELL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

EID: 84860710088     PISSN: 15257797     EISSN: 15264602     Source Type: Journal    
DOI: 10.1021/bm201639c     Document Type: Article

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