GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 27, Issue 2, 2007, Pages 422-429

  Hughan, Sascha C ^a,c   Hughes, Craig E ^a   McCarty, Owen J T ^a,e   Schweighoffer, Edina ^b   Soultanova, Izoumroud ^d   Ware, Jerry ^d   Tybulewicz, Victor L J ^b   Watson, Steve P ^a  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^c MONASH UNIVERSITY   (Australia)

^d UNIVERSITY OF ARKANSAS FOR MEDICAL SCIENCES   (United States)

^e Oregon Health and Science University Department of Biomedical Engineering   (United States)

Author keywords

GPVI signaling; Platelets; Src kinases; Syk; Thrombin

Indexed keywords

4 AMINO 7 TERT BUTYL 5 (4 CHLOROPHENYL)PYRAZOLO[3,4 D]PYRIMIDINE; ALPHA2BBETA3 INTEGRIN; C REACTIVE PROTEIN; CELL ADHESION MOLECULE; COLLAGEN; FC RECEPTOR; FIBRINOGEN; FIBRONECTIN; G PROTEIN COUPLED RECEPTOR; INTEGRIN; PROTEIN KINASE SYK; PROTEIN TYROSINE KINASE; THROMBIN; UNCLASSIFIED DRUG; VON WILLEBRAND FACTOR;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; LAMELLIPODIUM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; THROMBOCYTE ACTIVATION;

ANIMALS; C-REACTIVE PROTEIN; CELL ADHESION MOLECULES; CELL MEMBRANE; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICE, TRANSGENIC; PHOSPHORYLATION; PLATELET ACTIVATION; PLATELET AGGREGATION; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PLATELET MEMBRANE GLYCOPROTEINS; PROTEIN-TYROSINE KINASES; PSEUDOPODIA; PYRIMIDINES; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, PROTEINASE-ACTIVATED; SIGNAL TRANSDUCTION; SRC-FAMILY KINASES; THROMBIN; TYROSINE;

EID: 33846440543     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.0000252826.96134.21     Document Type: Article

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