ABCB1 haplotypes but not individual SNPs predict for optimal response/failure in Egyptian patients with chronic-phase chronic myeloid leukemia receiving imatinib mesylate

Medical Oncology

Volumn 31, Issue 11, 2014, Pages 1-10

  Ali, Mohamed A M ^a   Elsalakawy, Walaa Ali ^b  

^a Ain Shams University   (Egypt)

^b AIN SHAMS UNIVERSITY   (Egypt)

Author keywords

ATP binding cassette, subfamily B, member 1 (ABCB1); Chronic myeloid leukemia; Imatinib mesylate; Optimal response; Single nucleotide polymorphisms

Indexed keywords

IMATINIB; MULTIDRUG RESISTANCE PROTEIN 1; ABCB1 PROTEIN, HUMAN; ANTINEOPLASTIC AGENT; BENZAMIDE DERIVATIVE; MULTIDRUG RESISTANCE PROTEIN; PIPERAZINE DERIVATIVE; PYRIMIDINE DERIVATIVE;

ARTICLE; CANCER CHEMOTHERAPY; CHRONIC MYELOID LEUKEMIA; DRUG BIOAVAILABILITY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; PHILADELPHIA CHROMOSOME POSITIVE CELL; POLYMERASE CHAIN REACTION; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM; TREATMENT OUTCOME; ADULT; AGED; COHORT ANALYSIS; EGYPT; FEMALE; GENETICS; HUMAN; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MIDDLE AGED; PREDICTIVE VALUE; RETROSPECTIVE STUDY; TREATMENT FAILURE; YOUNG ADULT;

ADULT; AGED; ANTINEOPLASTIC AGENTS; BENZAMIDES; COHORT STUDIES; EGYPT; FEMALE; HAPLOTYPES; HUMANS; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; MALE; MIDDLE AGED; P-GLYCOPROTEINS; PIPERAZINES; POLYMORPHISM, SINGLE NUCLEOTIDE; PREDICTIVE VALUE OF TESTS; PYRIMIDINES; RETROSPECTIVE STUDIES; TREATMENT FAILURE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84919904935     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-014-0279-y     Document Type: Article

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