Denosumab rapidly increases cortical bone in key locations of the femur: A 3D bone mapping study in women with osteoporosis

Journal of Bone and Mineral Research

Volumn 30, Issue 1, 2015, Pages 46-54

  Poole, Kenneth E S ^a   Treece, Graham M ^b   Gee, Andrew H ^b   Brown, Jacques P ^c   McClung, Michael R ^d   Wang, Andrea ^d   Libanati, Cesar ^e  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^c UNIVERSITÉ LAVAL   (Canada)

^d OREGON OSTEOPOROSIS CENTER   (United States)

^e AMGEN INC   (United States)

Author keywords

Computational anatomy; Computed tomography; Denosumab; Female; Femoral neck fractures; HIP fracture; Osteoporosis; Postmenopausal osteoporosis

Indexed keywords

DENOSUMAB; PLACEBO; MONOCLONAL ANTIBODY;

ADULT; AGED; ARTICLE; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORTICAL BONE; CORTICAL THICKNESS (BONE); DENSITY; FEMALE; FEMUR; HIP; HIP FRACTURE; HUMAN; HYPOTHESIS; IMAGE ANALYSIS; MAJOR CLINICAL STUDY; OSTEOPOROSIS; PLACEBO EFFECT; POSTMENOPAUSE; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; SURFACE PROPERTY; THREE DIMENSIONAL IMAGING; TREATMENT OUTCOME; VERY ELDERLY; BONE DENSITY; CLINICAL TRIAL; DRUG EFFECTS; FEMUR NECK; FOLLOW UP; HIP FRACTURES; METABOLISM; MIDDLE AGED; MULTICENTER STUDY; OSTEOPOROSIS, POSTMENOPAUSAL; RADIOGRAPHY;

AGED; AGED, 80 AND OVER; ANTIBODIES, MONOCLONAL, HUMANIZED; BONE DENSITY; DENOSUMAB; FEMALE; FEMUR NECK; FOLLOW-UP STUDIES; HIP FRACTURES; HUMANS; MIDDLE AGED; OSTEOPOROSIS, POSTMENOPAUSAL; TOMOGRAPHY, X-RAY COMPUTED;

EID: 84919881052     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.2325     Document Type: Article

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