Proximal femoral density distribution and structure in relation to age and hip fracture risk in women

Journal of Bone and Mineral Research

Volumn 28, Issue 3, 2013, Pages 537-546

  Carballido Gamio, Julio ^a   Harnish, Roy ^a   Saeed, Isra ^a   Streeper, Timothy ^a   Sigurdsson, Sigurdur ^b   Amin, Shreyasee ^c   Atkinson, Elizabeth J ^c   Therneau, Terry M ^c   Siggeirsdottir, Kristin ^b   Cheng, Xiaoguang ^d   Melton III, L Joseph ^c   Keyak, Joyce ^f   Gudnason, Vilmundur ^b,g   Khosla, Sundeep ^c   Harris, Tamara B ^e   Lang, Thomas F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b ICELANDIC HEART ASSOCIATION   (Iceland)

^c MAYO CLINIC   (United States)

^d Jishuitan Orthopaedic College of Tsinghua University   (China)

^e NATIONAL INSTITUTE ON AGING   (United States)

^f UNIVERSITY OF CALIFORNIA   (United States)

^g UNIVERSITY OF ICELAND   (Iceland)

Author keywords

AGE; FRACTURE; OSTEOPOROSIS; PROXIMAL FEMUR; STATISTICAL PARAMETRIC MAPPING

Indexed keywords

BIOLOGICAL MARKER;

ADULT; AGE DISTRIBUTION; AGED; AGING; ARTICLE; ATLAS; BONE DENSITY; BONE STRUCTURE; COMPUTED TOMOGRAPHY SCANNER; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; CORTICAL BONE; DISEASE DURATION; DUAL ENERGY X RAY ABSORPTIOMETRY; FEMALE; FEMUR; HIP FRACTURE; HUMAN; IMAGE ANALYSIS; LOAD CARRYING CAPACITY; MAJOR CLINICAL STUDY; OSTEOLYSIS; PHENOTYPE; RISK FACTOR; SCALE UP; STUDENT T TEST; THREE DIMENSIONAL IMAGING; TRABECULAR BONE; VOXEL BASED MORPHOMETRY;

EID: 84873971103     PISSN: 08840431     EISSN: 15234681     Source Type: Journal    
DOI: 10.1002/jbmr.1802     Document Type: Article

References (37)

1. Burge R, Dawson-Hughes B, Solomon DH, Wong JB, King A, Tosteson A., Incidence and economic burden of osteoporosis-related fractures in the United States, 2005-2025. J Bone Miner Res. 2007; 22 (3): 465-75.
2. Mayhew PM, Thomas CD, Clement JG, Loveridge N, Beck TJ, Bonfield W, Burgoyne CJ, Reeve J., Relation between age, femoral neck cortical stability, and hip fracture risk. Lancet. 2005; 366 (9480): 129-35.
3. Thomas CD, Mayhew PM, Power J, Poole KE, Loveridge N, Clement JG, Burgoyne CJ, Reeve J., Femoral neck trabecular bone: loss with aging and role in preventing fracture. J Bone Miner Res. 2009; 24 (11): 1808-18.
4. Johannesdottir F, Poole KE, Reeve J, Siggeirsdottir K, Aspelund T, Mogensen B, Jonsson BY, Sigurdsson S, Harris TB, Gudnason VG, Sigurdsson G., Distribution of cortical bone in the femoral neck and hip fracture: a prospective case-control analysis of 143 incident hip fractures; the AGES-REYKJAVIK Study. Bone. 2011; 48 (6): 1268-76.
5. Bell KL, Loveridge N, Power J, Garrahan N, Stanton M, Lunt M, Meggitt BF, Reeve J., Structure of the femoral neck in hip fracture: cortical bone loss in the inferoanterior to superoposterior axis. J Bone Miner Res. 1999; 14 (1): 111-9.
6. Crabtree NJ, Kroger H, Martin A, Pols HA, Lorenc R, Nijs J, Stepan JJ, Falch JA, Miazgowski T, Grazio S, Raptou P, Adams J, Collings A, Khaw KT, Rushton N, Lunt M, Dixon AK, Reeve J., Improving risk assessment: hip geometry, bone mineral distribution and bone strength in hip fracture cases and controls. The EPOS study. European Prospective Osteoporosis Study. Osteoporos Int. 2002; 13 (1): 48-54.
7. Poole KE, Mayhew PM, Rose CM, Brown JK, Bearcroft PJ, Loveridge N, Reeve J., Changing structure of the femoral neck across the adult female lifespan. J Bone Miner Res. 2010; 25 (3): 482-91.
8. Poole KE, Treece GM, Mayhew PM, Vaculík J, Dungl P, Horák M, Štěpán JJ, Gee AH., Cortical thickness mapping to identify focal osteoporosis in patients with hip fracture. PloS One. 2012; 7 (6): e38466.
9. Ashburner J, Friston KJ., Voxel-based morphometry-the methods. Neuroimage. 2000; 11 (6 Pt 1): 805-21.
10. Riggs BL, Melton LJ 3rd, Robb RA, Camp JJ, Atkinson EJ, Peterson JM, Rouleau PA, McCollough CH, Bouxsein ML, Khosla S., Population-based study of age and sex differences in bone volumetric density, size, geometry, and structure at different skeletal sites. J Bone Miner Res. 2004; 19 (12): 1945-54.
11. Sigurdsson G, Aspelund T, Chang M, Jonsdottir B, Sigurdsson S, Eiriksdottir G, Gudmundsson A, Harris TB, Gudnason V, Lang TF., Increasing sex difference in bone strength in old age: The Age, Gene/Environment Susceptibility-Reykjavik study (AGES-REYKJAVIK). Bone. 2006; 39 (3): 644-51.
12. Harris TB, Launer LJ, Eiriksdottir G, Kjartansson O, Jonsson PV, Sigurdsson G, Thorgeirsson G, Aspelund T, Garcia ME, Cotch MF, Hoffman HJ, Gudnason V., Age, Gene/Environment Susceptibility-Reykjavik Study: multidisciplinary applied phenomics. Am J Epidemiol. 2007; 165 (9): 1076-87.
13. Siggeirsdottir K, Aspelund T, Sigurdsson G, Mogensen B, Chang M, Jonsdottir B, Eiriksdottir G, Launer LJ, Harris TB, Jonsson BY, Gudnason V., Inaccuracy in self-report of fractures may underestimate association with health outcomes when compared with medical record based fracture registry. Eur J Epidemiol. 2007; 22 (9): 631-9.
14. Keyak JH, Sigurdsson S, Karlsdottir G, Oskarsdottir D, Sigmarsdottir A, Zhao S, Kornak J, Harris TB, Sigurdsson G, Jonsson BY, Siggeirsdottir K, Eiriksdottir G, Gudnason V, Lang TF., Male-female differences in the association between incident hip fracture and proximal femoral strength: a finite element analysis study. Bone. 2011; 48 (6): 1239-45.
15. Keyak JH, Rossi SA, Jones KA, Skinner HB., Prediction of femoral fracture load using automated finite element modeling. J Biomech. 1998; 31 (2): 125-33.
16. Chung MK, Worsley KJ, Paus T, Cherif C, Collins DL, Giedd JN, Rapoport JL, Evans AC., A unified statistical approach to deformation-based morphometry. Neuroimage. 2001; 14 (3): 595-606.
17. Reinertsen I, Descoteaux M, Drouin S, Siddiqi K, Collins DL., Vessel driven correction of brain shift. Lecture Notes in Computer Science. Med Image Comput Comput Assist Interv. 2004; 3217: 208-16.
18. Suh JW, Wyatt CL., Deformable registration of prone and supine colons for CT colonography. Conf Proc IEEE Eng Med Biol Soc. 2006; 1: 1997-2000.
19. Hua X, Leow AD, Levitt JG, Caplan R, Thompson PM, Toga AW., Detecting brain growth patterns in normal children using tensor-based morphometry. Hum Brain Mapp. 2009; 30 (1): 209-19.
20. Vercauteren T, Pennec X, Perchant A, Ayache N., Non-parametric diffeomorphic image registration with the demons algorithm. Med Image Comput Comput Assist Interv. 2007; 10 (Pt 2): 319-26.
21. Mechelli A, Price CJ, Friston KJ, Ashburner J., Voxel-based morphometry of the human brain: methods and applications. Curr Med Imaging Rev. 2005; 1 (2): 105-13.
22. Chung MK, Dalton KM, Alexander AL, Davidson RJ., Less white matter concentration in autism: 2D voxel-based morphometry. Neuroimage. 2004; 23 (1): 242-51.
23. Campbell LE, Daly E, Toal F, Stevens A, Azuma R, Catani M, Ng V, van Amelsvoort T, Chitnis X, Cutter W, Murphy DG, Murphy KC., Brain and behaviour in children with 22q11.2 deletion syndrome: a volumetric and voxel-based morphometry MRI study. Brain. 2006; 129 (Pt 5): 1218-28.
24. Barnes J, Ridgway GR, Bartlett J, Henley SM, Lehmann M, Hobbs N, Clarkson MJ, MacManus DG, Ourselin S, Fox NC., Head size, age and gender adjustment in MRI studies: a necessary nuisance?. Neuroimage. 2010; 53 (4): 1244-55.
25. Genovese CR, Lazar NA, Nichols T., Thresholding of statistical maps in functional neuroimaging using the false discovery rate. Neuroimage. 2002; 15 (4): 870-8.
26. Kaptoge S, Dalzell N, Jakes RW, Wareham N, Day NE, Khaw KT, Beck TJ, Loveridge N, Reeve J., Hip section modulus, a measure of bending resistance, is more strongly related to reported physical activity than BMD. Osteoporos Int. 2003; 14 (11): 941-9.
27. Power J, Loveridge N, Lyon A, Rushton N, Parker M, Reeve J., Osteoclastic cortical erosion as a determinant of subperiosteal osteoblastic bone formation in the femoral neck's response to BMU imbalance. Effects of stance-related loading and hip fracture. Osteoporos Int. 2005; 16 (9): 1049-56.
28. Carpenter RD, Sigurdsson S, Zhao S, Lu Y, Eiriksdottir G, Sigurdsson G, Jonsson BY, Prevrhal S, Harris TB, Siggeirsdottir K, Guonason V, Lang TF., Effects of age and sex on the strength and cortical thickness of the femoral neck. Bone. 2011; 48 (4): 741-7.
29. Cheng X, Li J, Lu Y, Keyak J, Lang T., Proximal femoral density and geometry measurements by quantitative computed tomography: association with hip fracture. Bone. 2007; 40 (1): 169-74.
30. Ito M, Wakao N, Hida T, Matsui Y, Abe Y, Aoyagi K, Uetani M, Harada A., Analysis of hip geometry by clinical CT for the assessment of hip fracture risk in elderly Japanese women. Bone. 2010; 46 (2): 453-7.
31. Bousson VD, Adams J, Engelke K, Aout M, Cohen-Solal M, Bergot C, Haguenauer D, Goldberg D, Champion K, Aksouh R, Vicaut E, Laredo JD., In vivo discrimination of hip fracture with quantitative computed tomography: results from the prospective European Femur Fracture Study (EFFECT). J Bone Miner Res. 2011; 26 (4): 881-93.
32. Seeman E, Delmas PD., Bone quality-the material and structural basis of bone strength and fragility. N Engl J Med. 2006; 354 (21): 2250-61.
33. Bagi CM, Wilkie D, Georgelos K, Williams D, Bertolini D., Morphological and structural characteristics of the proximal femur in human and rat. Bone. 1997; 21 (3): 261-7.
34. Ominsky MS, Stouch B, Schroeder J, Pyrah I, Stolina M, Smith SY, Kostenuik PJ., Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys. Bone. 2011; 49 (2): 162-73.
35. Ominsky MS, Li C, Li X, Tan HL, Lee E, Barrero M, Asuncion FJ, Dwyer D, Han CY, Vlasseros F, Samadfam R, Jolette J, Smith SY, Stolina M, Lacey DL, Simonet WS, Paszty C, Li G, Ke HZ., Inhibition of sclerostin by monoclonal antibody enhances bone healing and improves bone density and strength of nonfractured bones. J Bone Miner Res. 2011; 26 (5): 1012-21.
36. Cusick T, Chen CM, Pennypacker BL, Pickarski M, Kimmel DB, Scott BB, Duong LT., Odanacatib treatment increases hip bone mass and cortical thickness by preserving endocortical bone formation and stimulating periosteal bone formation in the ovariectomized adult rhesus monkey. J Bone Miner Res. 2012; 27 (3): 524-37.
37. Jayakar RY, Cabal A, Szumiloski J, Sardesai S, Phillips EA, Laib A, Scott BB, Pickarski M, Duong le T, Winkelmann CT, McCracken PJ, Hargreaves R, Hangartner TN, Williams DS., Evaluation of high-resolution peripheral quantitative computed tomography, finite element analysis and biomechanical testing in a pre-clinical model of osteoporosis: a study with odanacatib treatment in the ovariectomized adult rhesus monkey. Bone. 2012; 50 (6): 1379-88.