Towards standardisation of cell-free DNA measurement in plasma: Controls for extraction efficiency, fragment size bias and quantification

Analytical and Bioanalytical Chemistry

Volumn 406, Issue 26, 2014, Pages 6499-6512

  Devonshire, Alison S ^a   Whale, Alexandra S ^a   Gutteridge, Alice ^a   Jones, Gerwyn ^a   Cowen, Simon ^a   Foy, Carole A ^a   Huggett, Jim F ^a  

^a LGC   (United Kingdom)

Author keywords

Cell free DNA; Circulating nucleic acids; Clinical biomedical analysis; Diagnostics; Liquid biopsy; Reference materials

Indexed keywords

BIOMOLECULES; DISEASES; DNA; EFFICIENCY; GENES; NUCLEIC ACID SEQUENCES; NUCLEIC ACIDS; PLASMA DIAGNOSTICS; POLYMERASE CHAIN REACTION; QUALITY CONTROL;

CANCER MONITORING; CELL-FREE; CLINICAL/BIOMEDICAL ANALYSIS; EXTRACTION EFFICIENCIES; EXTRACTION METHOD; MULTIPLE REFERENCES; REFERENCE MATERIAL; RELIABLE ESTIMATES;

EXTRACTION;

DIAGNOSTIC KIT; DNA;

BLOOD; DIAGNOSTIC KIT; FEMALE; HUMAN; ISOLATION AND PURIFICATION; MIDDLE AGED; PROCEDURES; REAL TIME POLYMERASE CHAIN REACTION; REPRODUCIBILITY; STANDARD; STANDARDS; VALIDATION STUDY;

DNA; FEMALE; HUMANS; MIDDLE AGED; REAGENT KITS, DIAGNOSTIC; REAL-TIME POLYMERASE CHAIN REACTION; REFERENCE STANDARDS; REPRODUCIBILITY OF RESULTS;

EID: 84919835602     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-7835-3     Document Type: Article

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