Accumulation of self-reactive naïve and memory B cell reveals sequential defects in B cell tolerance checkpoints in Sjögren's Syndrome

PLoS ONE

Volumn 9, Issue 12, 2014, Pages

  Corsiero, Elisa ^a   Sutcliffe, Nurhan ^a   Pitzalis, Costantino ^a   Bombardieri, Michele ^a   Reddy, Jay ^b  

^a QUEEN MARY UNIVERSITY OF LONDON   (United Kingdom)

^b UNIVERSITY OF NEBRASKA LINCOLN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD27 ANTIGEN; IMMUNOGLOBULIN D; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LIGHT CHAIN; ANTINUCLEAR ANTIBODY; IMMUNOGLOBULIN VARIABLE REGION;

ADULT; ARTICLE; BIOACCUMULATION; CELL CLONE; CELLULAR DISTRIBUTION; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; FLUORESCENCE ACTIVATED CELL SORTING; GENE SEQUENCE; HEP 2 CELL LINE; HUMAN; HUMAN CELL; IGVH GENE; IGVL GENE; IMMUNOGLOBULIN GENE; IMMUNOLOGICAL TOLERANCE; IMMUNOREACTIVITY; LYMPHOCYTE COUNT; MALE; MEMORY CELL; MIDDLE AGED; MUTATIONAL ANALYSIS; PATHOGENESIS; SJOEGREN SYNDROME; T LYMPHOCYTE SUBPOPULATION; AGED; B LYMPHOCYTE; CELL LINE; CELL SEPARATION; DONOR; GENETICS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGICAL MEMORY; IMMUNOLOGY; NUCLEOTIDE SEQUENCE;

ADULT; AGED; ANTIBODIES, ANTINUCLEAR; B-LYMPHOCYTES; CELL LINE; CELL SEPARATION; DNA MUTATIONAL ANALYSIS; FEMALE; HUMANS; IMMUNE TOLERANCE; IMMUNOGLOBULIN HEAVY CHAINS; IMMUNOGLOBULIN LIGHT CHAINS; IMMUNOGLOBULIN VARIABLE REGION; IMMUNOLOGIC MEMORY; MALE; MIDDLE AGED; SJOGREN'S SYNDROME; TISSUE DONORS;

EID: 84919797819     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0114575     Document Type: Article

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