HLA-A∗02:01:01/-B∗35:01:01/-C∗04:01:01 haplotype associated with lamotrigine-induced maculopapular exanthema in Mexican Mestizo patients

Pharmacogenomics

Volumn 15, Issue 15, 2014, Pages 1881-1891

  Fricke Galindo, Ingrid ^a   Martínez Juárez, Iris E ^b   Monroy Jaramillo, Nancy ^b   Jung Cook, Helgi ^b   Falfán Valencia, Ramcés ^c   Ortega Vázquez, Alberto ^a   Alonso Vilatela, María Elisa ^b   López López, Marisol ^a  

^a DEPARTAMENTO DE SISTEMAS BIOLÓGICOS   (Mexico)

^b NATIONAL INSTITUTE OF NEUROLOGY AND NEUROSURGERY   (Mexico)

^c INSTITUTO NACIONAL DE ENFERMEDADES RESPIRATORIAS   (Mexico)

Author keywords

antiepileptic drug; carbamazepine; cutaneous adverse drug reaction; exanthema maculopapular; human leukocyte antigen; lamotrigine; Mexican Mestizo; pharmacogenetics; phenytoin; Stevens Johnson syndrome

Indexed keywords

CARBAMAZEPINE; ETIRACETAM; LAMOTRIGINE; PHENYTOIN; HLA A ANTIGEN; HLA B ANTIGEN; HLA C ANTIGEN; TRIAZINE DERIVATIVE;

ADOLESCENT; ADULT; AGED; ARTICLE; CASE CONTROL STUDY; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG TOLERABILITY; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HAPLOTYPE; HLA A GENE; HLA B GENE; HLA C GENE; HUMAN; MACULOPAPULAR RASH; MALE; MESTIZO; MEXICAN; MIDDLE AGED; PEMPHIGUS; STEVENS JOHNSON SYNDROME; YOUNG ADULT; ADVERSE DRUG REACTION; AMERICAN INDIAN; DRUG ERUPTION; GENETICS; PATHOLOGY;

ADOLESCENT; ADULT; AGED; CARBAMAZEPINE; DRUG ERUPTIONS; DRUG-RELATED SIDE EFFECTS AND ADVERSE REACTIONS; FEMALE; GENETIC ASSOCIATION STUDIES; GENOTYPE; HAPLOTYPES; HLA-A ANTIGENS; HLA-B ANTIGENS; HLA-C ANTIGENS; HUMANS; INDIANS, NORTH AMERICAN; MALE; MIDDLE AGED; TRIAZINES;

EID: 84919788263     PISSN: 14622416     EISSN: 17448042     Source Type: Journal    
DOI: 10.2217/pgs.14.135     Document Type: Article

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