Oral Streptococci Utilize a Siglec-Like Domain of Serine-Rich Repeat Adhesins to Preferentially Target Platelet Sialoglycans in Human Blood

PLoS Pathogens

Volumn 10, Issue 12, 2014, Pages

  Deng, Lingquan ^a   Bensing, Barbara A ^b   Thamadilok, Supaporn ^c   Yu, Hai ^d   Lau, Kam ^d   Chen, Xi ^d   Ruhl, Stefan ^c   Sullam, Paul M ^b   Varki, Ajit ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY AT BUFFALO   (United States)

^d UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GLYCOCONJUGATE; MEMBRANE PROTEIN; SIALOGLYCOPROTEIN; SIGLEC LIKE DOMAIN OF SERINE RICH REPEAT ADHESIN; UNCLASSIFIED DRUG; ADHESIN; SIALIC ACID BINDING IMMUNOGLOBULIN LIKE LECTIN; VIRULENCE FACTOR;

ANTIGEN BINDING; ANTIGEN RECOGNITION; ARTICLE; BACTERIAL ENDOCARDITIS; BACTERIAL VIRULENCE; BLOOD SAMPLING; CONTROLLED STUDY; DOT HYBRIDIZATION; ENDOCARDIUM; FLOW CYTOMETRY; HEART VALVE; HEMAGGLUTINATION; HUMAN; NONHUMAN; PHYLOGENY; PROTEIN EXPRESSION; PROTEIN MICROARRAY; PROTEIN PURIFICATION; STREPTOCOCCUS; STREPTOCOCCUS GORDONII; STREPTOCOCCUS SANGUINIS; THROMBOCYTE; THROMBOCYTE ADHESION; BLOOD; CLINICAL TRIAL; FEMALE; MALE; METABOLISM; PATHOGENICITY;

EQUIDAE; POSIBACTERIA; STREPTOCOCCUS GORDONII; STREPTOCOCCUS SANGUINIS;

ADHESINS, BACTERIAL; BLOOD PLATELETS; ENDOCARDITIS, BACTERIAL; FEMALE; HUMANS; MALE; PROTEIN ARRAY ANALYSIS; SIALIC ACID BINDING IMMUNOGLOBULIN-LIKE LECTINS; STREPTOCOCCUS GORDONII; STREPTOCOCCUS SANGUIS; VIRULENCE FACTORS;

EID: 84919663410     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1004540     Document Type: Article

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