Determining the Size Dependence of Colloidal Gold Nanoparticle Uptake in a Tumor-like Interface (Hypoxic)

Colloids and Interface Science Communications

Volumn 1, Issue , 2014, Pages 57-61

  Neshatian, Mehrnoosh ^a   Chung, Stephen ^b   Yohan, Darren ^a   Yang, Celina ^a   Chithrani, Devika B ^a,c  

^a RYERSON UNIVERSITY   (Canada)

^b PRINCESS MARGARET HOSPITAL   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

Author keywords

Cancer therapy; Colloidal gold nanoparticles; Glycolysis; Hypoxia; Imaging; Mitochondrion; Nanoparticle uptake; Normoxia; Toxicity; Tumor

Indexed keywords

EID: 84919644343     PISSN: None     EISSN: 22150382     Source Type: Journal    
DOI: 10.1016/j.colcom.2014.07.004     Document Type: Article

References (25)

1. Chithrani B.D. Optimization of bio-nano interface using gold nanostructures as a model nanoparticle system. Insci. J. 2011, 1:136-156.
2. Jelveh S., Chithrani B.D. Gold nanostructures as a platform for combinational therapy in future cancer therapeutics. Cancer 2011, 3:1081-1110.
3. Jain S., Coulter J.A., Hounsell A.R., Butterworth K.T., McMahon S.J., Hyland W.B., Muir M.F., Dickson G.R., Prise K.M., Currell F.J., O'Sullivan J.M., Hirst D.G. Cell-specific radiosensitization by gold nanoparticles at megavoltage radiation energies. Int. J. Radiat. Oncol. Biol. Phys. 2011, 79:531-539.
4. Chithrani B.D., Ghazani A.A., Chan W.C.W. Determining the size and shape dependence of gold nanoparticle uptake into mammalian cells. Nano Lett. 2006, 6:662-668.
5. Gao H., Shi W., Freund L.B. Mechanics of receptor-mediated endocytosis. Proc. Natl. Acad. Sci. U. S. A. 2005, 102:9469-9474.
6. Zhang S., Li J., Lykotrafitis G., Bao G., Suresh S. Size-dependent endocytosis of nanoparticles. Adv. Mater. 2009, 21:419-424.
7. Moeller B.J., Rachel R.A., Richardson A., Dewhirst M.W. Hypoxia and radiotherapy: opportunities for improved outcomes in cancer treatment. Cancer Metastasis Rev. 2007, 26:241-248.
8. Dische S., Anderson P.J., Sealy R., Watson E.R. Carcinoma of the cervix-anaemia, radiotherapy and hyperbaric oxygen. Br. J. Radiol. 1983, 56:251-255.
9. Sullivan R., Paré G.C., Frederiksen L.J., Semenza G.L., Graham C.H. Hypoxia-induced resistance to anticancer drugs is associated with decreased senescence and requires hypoxia-inducible factor-1 activity. Mol. Cancer Ther. 2008, 7:1961-1973.
10. Chan N., Koch C.J., Bristow R.G. Tumor hypoxia as a modifier of DNA strand break and cross-link repair. Curr. Mol. Med. 2009, 9:401-410.
11. Hill R.P., Bristow R.G. The scientific basis of radiotherapy. The Basic Science of Oncology 2005, 289-321. McGraw-Hill Ltd., New York. I.F. Tannock, R.P. Hill, R.G. Bristow, L. Harrington (Eds.).
12. Luoto K.R., Kumareswaran R., Bristow R.G. Tumor hypoxia as a driving force in genetic instability. Genome Integr. 2013, 4:1-15.
13. Chithrani B.D. Nanoparticles for improved therapeutics and imaging in cancer therapy. Recent Pat. Nanotechnol. 2010, 4:171-180.
14. Hühn D., Kantner K., Geidel C., Brandholt S., De Cock I., Soenen S.J., Gil P.R., Martos J.M.M., Braeckmans K., Müllen K., Nienhaus G.U., Klapper M., Parak W.J. Polymer-coated nanoparticles interacting with proteins and cells: focusing on the sign of the net charge. ACS Nano 2013, 7:3253-3263.
15. Gil P.R., de Aberasturi D.J., Wulf V., Pelaz B., del Pino P., Zhao Y., de la Fuente J., de Larramendi I.R., Rojo T., Liang X.-J., Parak W.J. The challenge to relate the physicochemical properties of colloidal nanoparticles to their cytotoxicity. Acc. Chem. Res. 2013, 46:743-749.
16. Chithrani B.D. Intracellular uptake, transport, and processing of gold nanostructures. Mol. Membr. Biol. 2010, 27:299-311.
17. Chithrani B.D., Chan W.C.W. Elucidating the mechanism of cellular uptake and removal of protein-coated gold nanoparticles of different sizes and shapes. Nano Lett. 2007, 7:1542-1550.
18. Cairns R.A., Harris I.S., Mak T.W. Regulation of cancer cell metabolism. Nat. Rev. Cancer 2011, 11:85-95.
19. Seagroves T.N., Ryan H.E., Lu H., Wouters B.G., Knapp M., Thibault P., Laderoute K., Johnson R.S. Transcription factor HIF-1 is a necessary mediator of the Pasteur effect in mammalian cells. Mol. Cell. Biol. 2001, 21:3436-3444.
20. Gillies R.J., Robey I., Gatenby R.A. Causes and consequences of increased glucose metabolism of cancers. J. Nucl. Med. 2008, 49:24S-42S.
21. Takagi H., King G.L., Aiello L.P. Hypoxia upregulates glucose transport activity through an adenosine-mediated increase of GLUT1 expression in retinal capillary endothelial cells. Diabetes 1998, 47:1480-1488.
22. Ouiddir A., Planès C., Fernandes I., VanHesse A., Clerici C. Hypoxia upregulates activity and expression of the glucose transporter GLUT1 in alveolar epithelial cells. Am. J. Respir. Cell Mol. Biol. 1999, 21:710-718.
23. Jain S., Coulter J.A., Butterworth K.T., Hounsell A.R., McMahon S.J., Hyland W.B., Muir M.F., Dickson G.R., Prise K.M., Currell F.J., Hirst D.J., O'Sullivan J.M. Gold nanoparticle cellular uptake, toxicity and radiosensitisation in hypoxic conditions. Radiother. Oncol. 2014, 110:342-347.
24. Shorer H., Amar N., Meerson A., Elazar Z. Modulation of N-ethylmaleimide-sensitive factor activity upon amino acid deprivation. J. Biol. Chem. 2005, 280:16219-16226.
25. Ma X., Wu Y., Jin S., Tian Y., Zhang X., Zhao Y., Yu L., Liang X.-J. Gold nanoparticles induce autophagosome accumulation through size-dependent nanoparticle uptake and lysosome impairment. ACS Nano 2011, 5:8629-8639.