Decreased soluble adenylyl cyclase activity in cystic fibrosis is related to defective apical bicarbonate exchange and affects ciliary beat frequency regulation

Journal of Biological Chemistry

Volumn 285, Issue 39, 2010, Pages 29998-30007

  Schmid, Andreas ^a   Sutto, Zoltan ^a,b   Schmid, Nathalie ^a   Novak, Lisa ^a   Ivonnet, Pedro ^a   Horvath, Gabor ^a,c   Conner, Gregory ^a,b   Fregien, Nevis ^b   Salathe, Matthias ^a  

^a UNIVERSITY OF MIAMI   (United States)

^b UNIVERSITY OF MIAMI MILLER SCHOOL OF MEDICINE   (United States)

^c SEMMELWEIS UNIVERSITY OF MEDICINE   (Hungary)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOLOGY; FETAL MONITORING; FLUORESCENCE;

ADENYLYL CYCLASE; AIRWAY EPITHELIAL CELLS; CARBOXYFLUORESCEIN; CILIARY BEAT FREQUENCIES; CILIATED CELLS; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATORS; FLUORESCENCE RATIO; HUMAN AIRWAY; IN-CELL; INTRACELLULAR ACIDIFICATIONS; ISOFORMS; PERMEABILIZATION; PROTEIN KINASE; WESTERN BLOTS;

CELLS;

2',7' BIS(2 CARBOXYETHYL) 5(6) CARBOXYFLUORESCEIN; ADENYLATE CYCLASE; BICARBONATE; CALCIUM; CARBON DIOXIDE; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; FLUORESCENT DYE; ISOPROTEIN; TRANSMEMBRANE CONDUCTANCE REGULATOR; UNCLASSIFIED DRUG; 2',7'-BIS(CARBOXYETHYL)-5(6)-CARBOXYFLUORESCEIN; CFTR PROTEIN, HUMAN; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FLUORESCEIN DERIVATIVE;

ACIDIFICATION; ANION EXCHANGE; ANION TRANSPORT; ARTICLE; CALCIUM TRANSPORT; CARBON DIOXIDE TRANSPORT; CELL PERMEABILIZATION; CELL PH; CELL SPECIFICITY; CHLORIDE CONDUCTANCE; CILIARY BEAT FREQUENCY; CONTROLLED STUDY; CYSTIC FIBROSIS; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EPITHELIUM CELL; FLUORESCENCE; FLUORESCENCE RESONANCE ENERGY TRANSFER; HUMAN; HUMAN CELL; PERFUSION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RESPIRATORY EPITHELIUM; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; ENZYMOLOGY; EUKARYOTIC FLAGELLUM; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; RESPIRATORY TRACT MUCOSA;

ADENYLATE CYCLASE; BICARBONATES; CILIA; CYCLIC AMP; CYSTIC FIBROSIS; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FLUORESCEINS; HUMANS; RESPIRATORY MUCOSA;

EID: 77956936528     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.113621     Document Type: Article

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