메뉴 건너뛰기




Volumn 10, Issue 12, 2014, Pages

Genome Wide Meta-analysis Highlights the Role of Genetic Variation in RARRES2 in the Regulation of Circulating Serum Chemerin

(26)  Tönjes, Anke a   Scholz, Markus a   Breitfeld, Jana a   Marzi, Carola b,c   Grallert, Harald b,c   Gross, Arnd a   Ladenvall, Claes d   Schleinitz, Dorit a   Krause, Kerstin a   Kirsten, Holger a,e   Laurila, Esa d   Kriebel, Jennifer b   Thorand, Barbara b   Rathmann, Wolfgang f   Groop, Leif d   Prokopenko, Inga g,h,i   Isomaa, Bo j,k   Beutner, Frank l   Kratzsch, Jürgen l   Thiery, Joachim l   more..


Author keywords

[No Author keywords available]

Indexed keywords

CHEMERIN; MESSENGER RNA; CHEMERIN PROTEIN, HUMAN; CHEMOKINE; SIGNAL PEPTIDE;

EID: 84919594987     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1004854     Document Type: Article
Times cited : (33)

References (36)
  • 1
    • 34748817386 scopus 로고    scopus 로고
    • Chemerin is a novel adipokine associated with obesity and metabolic syndrome
    • Bozaoglu K, Bolton K, McMillan J, Zimmet P, Jowett J, et al. (2007) Chemerin is a novel adipokine associated with obesity and metabolic syndrome. Endocrinology 148: 4687–4694.
    • (2007) Endocrinology , vol.148 , pp. 4687-4694
    • Bozaoglu, K.1    Bolton, K.2    McMillan, J.3    Zimmet, P.4    Jowett, J.5
  • 2
    • 68549109421 scopus 로고    scopus 로고
    • Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population
    • Bozaoglu K, Segal D, Shields KA, Cummings N, Curran JE, et al. (2009) Chemerin is associated with metabolic syndrome phenotypes in a Mexican-American population. J Clin Endocrinol Metab 94: 3085–3088.
    • (2009) J Clin Endocrinol Metab , vol.94 , pp. 3085-3088
    • Bozaoglu, K.1    Segal, D.2    Shields, K.A.3    Cummings, N.4    Curran, J.E.5
  • 3
    • 68349146816 scopus 로고    scopus 로고
    • Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis
    • Lehrke M, Becker A, Greif M, Stark R, Laubender RP, et al. (2009) Chemerin is associated with markers of inflammation and components of the metabolic syndrome but does not predict coronary atherosclerosis. Eur J Endocrinol 161: 339–344.
    • (2009) Eur J Endocrinol , vol.161 , pp. 339-344
    • Lehrke, M.1    Becker, A.2    Greif, M.3    Stark, R.4    Laubender, R.P.5
  • 4
    • 77954795110 scopus 로고    scopus 로고
    • Circulating levels of the adipokine chemerin in gestational diabetes mellitus
    • Pfau D, Stepan H, Kratzsch J, Verlohren M, Verlohren HJ, et al. (2010) Circulating levels of the adipokine chemerin in gestational diabetes mellitus. Horm Res Paediatr 74: 56–61.
    • (2010) Horm Res Paediatr , vol.74 , pp. 56-61
    • Pfau, D.1    Stepan, H.2    Kratzsch, J.3    Verlohren, M.4    Verlohren, H.J.5
  • 5
    • 34948836879 scopus 로고    scopus 로고
    • Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism
    • Goralski KB, McCarthy TC, Hanniman EA, Zabel BA, Butcher EC, et al. (2007) Chemerin, a novel adipokine that regulates adipogenesis and adipocyte metabolism. J Biol Chem 282: 28175–28188.
    • (2007) J Biol Chem , vol.282 , pp. 28175-28188
    • Goralski, K.B.1    McCarthy, T.C.2    Hanniman, E.A.3    Zabel, B.A.4    Butcher, E.C.5
  • 6
    • 0141993969 scopus 로고    scopus 로고
    • Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids
    • Wittamer V, Franssen JD, Vulcano M, Mirjolet JF, Le Poul E, et al. (2003) Specific recruitment of antigen-presenting cells by chemerin, a novel processed ligand from human inflammatory fluids. J Exp Med 198: 977–985.
    • (2003) J Exp Med , vol.198 , pp. 977-985
    • Wittamer, V.1    Franssen, J.D.2    Vulcano, M.3    Mirjolet, J.F.4    Le Poul, E.5
  • 7
    • 27144444137 scopus 로고    scopus 로고
    • Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades
    • Zabel BA, Allen SJ, Kulig P, Allen JA, Cichy J, et al. (2005) Chemerin activation by serine proteases of the coagulation, fibrinolytic, and inflammatory cascades. J Biol Chem 280: 34661–34666.
    • (2005) J Biol Chem , vol.280 , pp. 34661-34666
    • Zabel, B.A.1    Allen, S.J.2    Kulig, P.3    Allen, J.A.4    Cichy, J.5
  • 9
    • 62349142248 scopus 로고    scopus 로고
    • RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study
    • Mussig K, Staiger H, Machicao F, Thamer C, Machann J, et al. (2009) RARRES2, encoding the novel adipokine chemerin, is a genetic determinant of disproportionate regional body fat distribution: a comparative magnetic resonance imaging study. Metabolism 58: 519–524.
    • (2009) Metabolism , vol.58 , pp. 519-524
    • Mussig, K.1    Staiger, H.2    Machicao, F.3    Thamer, C.4    Machann, J.5
  • 10
    • 84867334127 scopus 로고    scopus 로고
    • Association between chemerin rs17173608 and vaspin rs2236242 gene polymorphisms and the metabolic syndrome, a preliminary report
    • Hashemi M, Rezaei H, Eskandari-Nasab E, Kaykhaei MA, Zakeri Z, et al. (2012) Association between chemerin rs17173608 and vaspin rs2236242 gene polymorphisms and the metabolic syndrome, a preliminary report. Gene 510: 113–117.
    • (2012) Gene , vol.510 , pp. 113-117
    • Hashemi, M.1    Rezaei, H.2    Eskandari-Nasab, E.3    Kaykhaei, M.A.4    Zakeri, Z.5
  • 11
    • 84859204533 scopus 로고    scopus 로고
    • Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes
    • Min JL, Nicholson G, Halgrimsdottir I, Almstrup K, Petri A, et al. (2012) Coexpression network analysis in abdominal and gluteal adipose tissue reveals regulatory genetic loci for metabolic syndrome and related phenotypes. PLoS Genet 8: e1002505.
    • (2012) PLoS Genet , vol.8 , pp. 1002505
    • Min, J.L.1    Nicholson, G.2    Halgrimsdottir, I.3    Almstrup, K.4    Petri, A.5
  • 12
    • 44249112333 scopus 로고    scopus 로고
    • A genomic background based method for association analysis in related individuals
    • Amin N, van Duijn CM, Aulchenko YS, (2007) A genomic background based method for association analysis in related individuals. PLoS One 2: e1274.
    • (2007) PLoS One , vol.2 , pp. 1274
    • Amin, N.1    van Duijn, C.M.2    Aulchenko, Y.S.3
  • 13
    • 35048838105 scopus 로고    scopus 로고
    • Genomewide rapid association using mixed model and regression: a fast and simple method for genomewide pedigree-based quantitative trait loci association analysis
    • Aulchenko YS, de Koning DJ, Haley C, (2007) Genomewide rapid association using mixed model and regression: a fast and simple method for genomewide pedigree-based quantitative trait loci association analysis. Genetics 177: 577–585.
    • (2007) Genetics , vol.177 , pp. 577-585
    • Aulchenko, Y.S.1    de Koning, D.J.2    Haley, C.3
  • 14
    • 67249117049 scopus 로고    scopus 로고
    • Potential etiologic and functional implications of genome-wide association loci for human diseases and traits
    • Hindorff LA, Sethupathy P, Junkins HA, Ramos EM, Mehta JP, et al. (2009) Potential etiologic and functional implications of genome-wide association loci for human diseases and traits. Proc Natl Acad Sci U S A 106: 9362–9367.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 9362-9367
    • Hindorff, L.A.1    Sethupathy, P.2    Junkins, H.A.3    Ramos, E.M.4    Mehta, J.P.5
  • 15
    • 84055216956 scopus 로고    scopus 로고
    • Rationale and design of the Leipzig (LIFE) Heart Study: phenotyping and cardiovascular characteristics of patients with coronary artery disease
    • Beutner F, Teupser D, Gielen S, Holdt LM, Scholz M, et al. (2011) Rationale and design of the Leipzig (LIFE) Heart Study: phenotyping and cardiovascular characteristics of patients with coronary artery disease. PLoS One 6: e29070.
    • (2011) PLoS One , vol.6 , pp. 29070
    • Beutner, F.1    Teupser, D.2    Gielen, S.3    Holdt, L.M.4    Scholz, M.5
  • 17
    • 55449112450 scopus 로고    scopus 로고
    • High-resolution mapping of expression-QTLs yields insight into human gene regulation
    • Veyrieras JB, Kudaravalli S, Kim SY, Dermitzakis ET, Gilad Y, et al. (2008) High-resolution mapping of expression-QTLs yields insight into human gene regulation. PLoS Genet 4: e1000214.
    • (2008) PLoS Genet , vol.4 , pp. 1000214
    • Veyrieras, J.B.1    Kudaravalli, S.2    Kim, S.Y.3    Dermitzakis, E.T.4    Gilad, Y.5
  • 18
    • 84904721826 scopus 로고    scopus 로고
    • Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes
    • Stienstra R, Haim Y, Riahi Y, Netea M, Rudich A, et al. (2014) Autophagy in adipose tissue and the beta cell: implications for obesity and diabetes. Diabetologia 57: 1505–1516.
    • (2014) Diabetologia , vol.57 , pp. 1505-1516
    • Stienstra, R.1    Haim, Y.2    Riahi, Y.3    Netea, M.4    Rudich, A.5
  • 19
    • 73949124173 scopus 로고    scopus 로고
    • Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis
    • Zhang Y, Goldman S, Baerga R, Zhao Y, Komatsu M, et al. (2009) Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis. Proc Natl Acad Sci U S A 106: 19860–19865.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 19860-19865
    • Zhang, Y.1    Goldman, S.2    Baerga, R.3    Zhao, Y.4    Komatsu, M.5
  • 20
    • 70449448312 scopus 로고    scopus 로고
    • Autophagy regulates adipose mass and differentiation in mice
    • Singh R, Xiang Y, Wang Y, Baikati K, Cuervo AM, et al. (2009) Autophagy regulates adipose mass and differentiation in mice. J Clin Invest 119: 3329–3339.
    • (2009) J Clin Invest , vol.119 , pp. 3329-3339
    • Singh, R.1    Xiang, Y.2    Wang, Y.3    Baikati, K.4    Cuervo, A.M.5
  • 21
    • 84865712382 scopus 로고    scopus 로고
    • Annotation of functional variation in personal genomes using RegulomeDB
    • Boyle AP, Hong EL, Hariharan M, Cheng Y, Schaub MA, et al. (2012) Annotation of functional variation in personal genomes using RegulomeDB. Genome Res 22: 1790–1797.
    • (2012) Genome Res , vol.22 , pp. 1790-1797
    • Boyle, A.P.1    Hong, E.L.2    Hariharan, M.3    Cheng, Y.4    Schaub, M.A.5
  • 23
    • 33644876958 scopus 로고    scopus 로고
    • TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes
    • Matys V, Kel-Margoulis OV, Fricke E, Liebich I, Land S, et al. (2006) TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotes. Nucleic Acids Res 34: D108–D110.
    • (2006) Nucleic Acids Res , vol.34 , pp. D108-D110
    • Matys, V.1    Kel-Margoulis, O.V.2    Fricke, E.3    Liebich, I.4    Land, S.5
  • 24
    • 79952266465 scopus 로고    scopus 로고
    • Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data
    • Pique-Regi R, Degner JF, Pai AA, Gaffney DJ, Gilad Y, et al. (2011) Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data. Genome Res 21: 447–455.
    • (2011) Genome Res , vol.21 , pp. 447-455
    • Pique-Regi, R.1    Degner, J.F.2    Pai, A.A.3    Gaffney, D.J.4    Gilad, Y.5
  • 25
    • 84882253920 scopus 로고    scopus 로고
    • Genetic variation in the vaspin gene affects circulating serum vaspin concentrations
    • Breitfeld J, Tonjes A, Bottcher Y, Schleinitz D, Wiele N, et al. (2013) Genetic variation in the vaspin gene affects circulating serum vaspin concentrations. Int J Obes (Lond) 37: 861–866.
    • (2013) Int J Obes (Lond) , vol.37 , pp. 861-866
    • Breitfeld, J.1    Tonjes, A.2    Bottcher, Y.3    Schleinitz, D.4    Wiele, N.5
  • 26
    • 79960656505 scopus 로고    scopus 로고
    • Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays
    • Gross A, Tonjes A, Kovacs P, Veeramah KR, Ahnert P, et al. (2011) Population-genetic comparison of the Sorbian isolate population in Germany with the German KORA population using genome-wide SNP arrays. BMC Genet 12: 67.
    • (2011) BMC Genet , vol.12 , pp. 67
    • Gross, A.1    Tonjes, A.2    Kovacs, P.3    Veeramah, K.R.4    Ahnert, P.5
  • 27
    • 70449334180 scopus 로고    scopus 로고
    • Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs
    • Tonjes A, Koriath M, Schleinitz D, Dietrich K, Bottcher Y, et al. (2009) Genetic variation in GPR133 is associated with height: genome wide association study in the self-contained population of Sorbs. Hum Mol Genet 18: 4662–4668.
    • (2009) Hum Mol Genet , vol.18 , pp. 4662-4668
    • Tonjes, A.1    Koriath, M.2    Schleinitz, D.3    Dietrich, K.4    Bottcher, Y.5
  • 28
    • 80052028100 scopus 로고    scopus 로고
    • Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity
    • Veeramah KR, Tonjes A, Kovacs P, Gross A, Wegmann D, et al. (2011) Genetic variation in the Sorbs of eastern Germany in the context of broader European genetic diversity. Eur J Hum Genet 19: 995–1001.
    • (2011) Eur J Hum Genet , vol.19 , pp. 995-1001
    • Veeramah, K.R.1    Tonjes, A.2    Kovacs, P.3    Gross, A.4    Wegmann, D.5
  • 29
    • 23844472247 scopus 로고    scopus 로고
    • KORA-gen–resource for population genetics, controls and a broad spectrum of disease phenotypes
    • Wichmann HE, Gieger C, Illig T, (2005) KORA-gen–resource for population genetics, controls and a broad spectrum of disease phenotypes. Gesundheitswesen 67 Suppl 1: S26–S30.
    • (2005) Gesundheitswesen , vol.67 , pp. S26-S30
    • Wichmann, H.E.1    Gieger, C.2    Illig, T.3
  • 30
    • 77955515264 scopus 로고    scopus 로고
    • A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study
    • Isomaa B, Forsen B, Lahti K, Holmstrom N, Waden J, et al. (2010) A family history of diabetes is associated with reduced physical fitness in the Prevalence, Prediction and Prevention of Diabetes (PPP)-Botnia study. Diabetologia 53: 1709–1713.
    • (2010) Diabetologia , vol.53 , pp. 1709-1713
    • Isomaa, B.1    Forsen, B.2    Lahti, K.3    Holmstrom, N.4    Waden, J.5
  • 31
    • 34249888775 scopus 로고    scopus 로고
    • Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels
    • Saxena R, Voight BF, Lyssenko V, Burtt NP, de Bakker PI, et al. (2007) Genome-wide association analysis identifies loci for type 2 diabetes and triglyceride levels. Science 316: 1331–1336.
    • (2007) Science , vol.316 , pp. 1331-1336
    • Saxena, R.1    Voight, B.F.2    Lyssenko, V.3    Burtt, N.P.4    de Bakker, P.I.5
  • 32
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price AL, Patterson NJ, Plenge RM, Weinblatt ME, Shadick NA, et al. (2006) Principal components analysis corrects for stratification in genome-wide association studies. Nat Genet 38: 904–909.
    • (2006) Nat Genet , vol.38 , pp. 904-909
    • Price, A.L.1    Patterson, N.J.2    Plenge, R.M.3    Weinblatt, M.E.4    Shadick, N.A.5
  • 33
    • 0000878807 scopus 로고    scopus 로고
    • The distribution of the instrumental variables estimator and its t-ratio when the instrument is a poor one
    • Nelson C, Startz R, The distribution of the instrumental variables estimator and its t-ratio when the instrument is a poor one. J Business 63: 125–140.
    • J Business , vol.63 , pp. 125-140
    • Nelson, C.1    Startz, R.2
  • 34
    • 33845432928 scopus 로고    scopus 로고
    • Adjusting batch effects in microarray expression data using empirical Bayes methods
    • Johnson WE, Li C, Rabinovic A, (2007) Adjusting batch effects in microarray expression data using empirical Bayes methods. Biostatistics 8: 118–127.
    • (2007) Biostatistics , vol.8 , pp. 118-127
    • Johnson, W.E.1    Li, C.2    Rabinovic, A.3
  • 35
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, et al. (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 412–419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5
  • 36
    • 0034835295 scopus 로고    scopus 로고
    • Oral glucose tolerance test indexes for insulin sensitivity and secretion based on various availabilities of sampling times
    • Stumvoll M, Van Haeften T, Fritsche A, Gerich J, (2001) Oral glucose tolerance test indexes for insulin sensitivity and secretion based on various availabilities of sampling times. Diabetes Care 24: 796–797.
    • (2001) Diabetes Care , vol.24 , pp. 796-797
    • Stumvoll, M.1    Van Haeften, T.2    Fritsche, A.3    Gerich, J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.