Reliable reconstruction of HIV-1 whole genome haplotypes reveals clonal interference and genetic hitchhiking among immune escape variants

Retrovirology

Volumn 11, Issue 1, 2014, Pages

  Pandit, Aridaman ^a   de Boer, Rob J ^a  

^a UTRECHT UNIVERSITY   (Netherlands)

Author keywords

Clonal interference; Genetic hitchhiking; Haplotype reconstruction; HIV 1 genome; Next generation sequencing

Indexed keywords

EPITOPE;

ARTICLE; CLONAL SPECIES; FEASIBILITY STUDY; GENE AMPLIFICATION; GENE CONSTRUCT; GENE FREQUENCY; GENE SEQUENCE; GENETIC DRIFT; GENOME ANALYSIS; HAPLOTYPE; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS INFECTED PATIENT; NUCLEOTIDE SEQUENCE; PHYLOGENY; PREDICTION; RELIABILITY; SELECTIVE SWEEP; SIMULATION; VALIDATION STUDY; VIRUS GENE; VIRUS GENOME; VIRUS IMMUNITY; VIRUS MUTATION; CYTOTOXIC T LYMPHOCYTE; GENETICS; HUMAN; IMMUNE EVASION; IMMUNOLOGY; CLONAL INTERFERENCE; CONTROLLED STUDY; GENETIC PARAMETERS; GENETIC VARIABILITY; IMMUNE ESCAPE VARIANT; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; NONHUMAN; PHYLOGENETIC TREE; VALIDATION PROCESS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EPITOPES, T-LYMPHOCYTE; GENOME, VIRAL; HAPLOTYPES; HIV-1; HUMANS; IMMUNE EVASION; PHYLOGENY; T-LYMPHOCYTES, CYTOTOXIC;

EID: 84919499306     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-11-56     Document Type: Article

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