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Volumn 76, Issue 3, 2014, Pages 173-179

Cathelicidin peptide LL-37 increases UVB-triggered inflammasome activation: Possible implications for rosacea

Author keywords

Angiogenesis; Cathelicidin LL 37; Inflammasome; P2X7; Rosacea; UVB

Indexed keywords

CALCIUM; CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; INFLAMMASOME; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; PURINERGIC P2X7 RECEPTOR; ANTIMICROBIAL CATIONIC PEPTIDE; AUTACOID; CAP18 LIPOPOLYSACCHARIDE-BINDING PROTEIN;

EID: 84919492128     PISSN: 09231811     EISSN: 1873569X     Source Type: Journal    
DOI: 10.1016/j.jdermsci.2014.09.002     Document Type: Article
Times cited : (63)

References (45)
  • 1
    • 84887884169 scopus 로고    scopus 로고
    • Rosacea: current state of epidemiology
    • Tan J., Berg M. Rosacea: current state of epidemiology. J Am Acad Dermatol 2013, 69:S27-S35.
    • (2013) J Am Acad Dermatol , vol.69 , pp. S27-S35
    • Tan, J.1    Berg, M.2
  • 2
    • 36849050206 scopus 로고    scopus 로고
    • The enigma of rosacea
    • Marks R. The enigma of rosacea. J Dermatolog Treat 2007, 18:326-328.
    • (2007) J Dermatolog Treat , vol.18 , pp. 326-328
    • Marks, R.1
  • 4
    • 78650986541 scopus 로고    scopus 로고
    • Rosacea-global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert Group
    • Elewski B.E., Draelos Z., Dreno B., Jansen T., Layton A., Picardo M. Rosacea-global diversity and optimized outcome: proposed international consensus from the Rosacea International Expert Group. J Eur Acad Dermatol Venereol 2011, 25:188-200.
    • (2011) J Eur Acad Dermatol Venereol , vol.25 , pp. 188-200
    • Elewski, B.E.1    Draelos, Z.2    Dreno, B.3    Jansen, T.4    Layton, A.5    Picardo, M.6
  • 5
    • 4444315851 scopus 로고    scopus 로고
    • Rosacea: I.Etiology, pathogenesis, and subtype classification
    • (quiz 342-4)
    • Crawford G.H., Pelle M.T., James W.D., Rosacea: I.Etiology, pathogenesis, and subtype classification J Am Acad Dermatol 2004, 51(327):41. (quiz 342-4).
    • (2004) J Am Acad Dermatol , vol.51 , Issue.327 , pp. 41
    • Crawford, G.H.1    Pelle, M.T.2    James, W.D.3
  • 7
    • 84884353255 scopus 로고    scopus 로고
    • Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel
    • Coda A.B., Hata T., Miller J., Audish D., Kotol P., Two A., et al. Cathelicidin, kallikrein 5, and serine protease activity is inhibited during treatment of rosacea with azelaic acid 15% gel. J Am Acad Dermatol 2013, 69:570-577.
    • (2013) J Am Acad Dermatol , vol.69 , pp. 570-577
    • Coda, A.B.1    Hata, T.2    Miller, J.3    Audish, D.4    Kotol, P.5    Two, A.6
  • 8
    • 79951786934 scopus 로고    scopus 로고
    • Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosacea
    • Zhang J., Xu X., Rao N.V., Argyle B., McCoard L., Rusho W.J., et al. Novel sulfated polysaccharides disrupt cathelicidins, inhibit RAGE and reduce cutaneous inflammation in a mouse model of rosacea. PLoS One 2011, 6:e16658.
    • (2011) PLoS One , vol.6 , pp. e16658
    • Zhang, J.1    Xu, X.2    Rao, N.V.3    Argyle, B.4    McCoard, L.5    Rusho, W.J.6
  • 9
    • 80955136390 scopus 로고    scopus 로고
    • Rosacea as a disease of cathelicidins and skin innate immunity
    • Yamasaki K., Gallo R.L. Rosacea as a disease of cathelicidins and skin innate immunity. J Investig Dermatol Symp Proc 2011, 15:12-15.
    • (2011) J Investig Dermatol Symp Proc , vol.15 , pp. 12-15
    • Yamasaki, K.1    Gallo, R.L.2
  • 10
    • 67649774232 scopus 로고    scopus 로고
    • The molecular pathology of rosacea
    • Yamasaki K., Gallo R.L. The molecular pathology of rosacea. J Dermatol Sci 2009, 55:77-81.
    • (2009) J Dermatol Sci , vol.55 , pp. 77-81
    • Yamasaki, K.1    Gallo, R.L.2
  • 11
    • 34547660319 scopus 로고    scopus 로고
    • Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea
    • Yamasaki K., Di Nardo A., Bardan A., Murakami M., Ohtake T., Coda A., et al. Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea. Nat Med 2007, 13:975-980.
    • (2007) Nat Med , vol.13 , pp. 975-980
    • Yamasaki, K.1    Di Nardo, A.2    Bardan, A.3    Murakami, M.4    Ohtake, T.5    Coda, A.6
  • 12
    • 84874796449 scopus 로고    scopus 로고
    • Rosacea: update on management and emerging therapies
    • Fallen R.S., Gooderham M. Rosacea: update on management and emerging therapies. Skin Therapy Lett 2012, 17:1-4.
    • (2012) Skin Therapy Lett , vol.17 , pp. 1-4
    • Fallen, R.S.1    Gooderham, M.2
  • 13
    • 0842326097 scopus 로고    scopus 로고
    • Cathelicidins, multifunctional peptides of the innate immunity
    • Zanetti M. Cathelicidins, multifunctional peptides of the innate immunity. J Leukoc Biol 2004, 75:39-48.
    • (2004) J Leukoc Biol , vol.75 , pp. 39-48
    • Zanetti, M.1
  • 14
    • 48349087831 scopus 로고    scopus 로고
    • Antimicrobial peptides and the skin immune defense system
    • Schauber J., Gallo R.L. Antimicrobial peptides and the skin immune defense system. J Allergy Clin Immunol 2008, 122:261-266.
    • (2008) J Allergy Clin Immunol , vol.122 , pp. 261-266
    • Schauber, J.1    Gallo, R.L.2
  • 15
    • 33750139445 scopus 로고    scopus 로고
    • Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin
    • Yamasaki K., Schauber J., Coda A., Lin H., Dorschner R.A., Schechter N.M., et al. Kallikrein-mediated proteolysis regulates the antimicrobial effects of cathelicidins in skin. FASEB J 2006, 20:2068-2080.
    • (2006) FASEB J , vol.20 , pp. 2068-2080
    • Yamasaki, K.1    Schauber, J.2    Coda, A.3    Lin, H.4    Dorschner, R.A.5    Schechter, N.M.6
  • 18
    • 84857536801 scopus 로고    scopus 로고
    • Antimicrobial peptides in the pathogenesis of psoriasis
    • Morizane S., Gallo R.L. Antimicrobial peptides in the pathogenesis of psoriasis. J Dermatol 2012, 39:225-230.
    • (2012) J Dermatol , vol.39 , pp. 225-230
    • Morizane, S.1    Gallo, R.L.2
  • 19
    • 78651400695 scopus 로고    scopus 로고
    • The coordinated response of the physical and antimicrobial peptide barriers of the skin
    • Borkowski A.W., Gallo R.L. The coordinated response of the physical and antimicrobial peptide barriers of the skin. J Invest Dermatol 2011, 131:285-287.
    • (2011) J Invest Dermatol , vol.131 , pp. 285-287
    • Borkowski, A.W.1    Gallo, R.L.2
  • 20
    • 79951516747 scopus 로고    scopus 로고
    • TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes
    • Yamasaki K., Kanada K., Macleod D.T., Borkowski A.W., Morizane S., Nakatsuji T., et al. TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes. J Invest Dermatol 2011, 131:688-697.
    • (2011) J Invest Dermatol , vol.131 , pp. 688-697
    • Yamasaki, K.1    Kanada, K.2    Macleod, D.T.3    Borkowski, A.W.4    Morizane, S.5    Nakatsuji, T.6
  • 21
    • 84870048090 scopus 로고    scopus 로고
    • Quantification of Demodex folliculorum by PCR in rosacea and its relationship to skin innate immune activation
    • Casas C., Paul C., Lahfa M., Livideanu B., Lejeune O., Alvarez-Georges S., et al. Quantification of Demodex folliculorum by PCR in rosacea and its relationship to skin innate immune activation. Exp Dermatol 2012, 21:906-910.
    • (2012) Exp Dermatol , vol.21 , pp. 906-910
    • Casas, C.1    Paul, C.2    Lahfa, M.3    Livideanu, B.4    Lejeune, O.5    Alvarez-Georges, S.6
  • 23
    • 2342522112 scopus 로고    scopus 로고
    • Interleukin-1beta regulates angiopoietin-1 expression in human endothelial cells
    • Fan F., Stoeltzing O., Liu W., McCarty M.F., Jung Y.D., Reinmuth N., et al. Interleukin-1beta regulates angiopoietin-1 expression in human endothelial cells. Cancer Res 2004, 64:3186-3190.
    • (2004) Cancer Res , vol.64 , pp. 3186-3190
    • Fan, F.1    Stoeltzing, O.2    Liu, W.3    McCarty, M.F.4    Jung, Y.D.5    Reinmuth, N.6
  • 24
    • 84890235827 scopus 로고    scopus 로고
    • The interleukin-1 family: back to the future
    • Garlanda C., Dinarello C.A., Mantovani A. The interleukin-1 family: back to the future. Immunity 2013, 39:1003-1018.
    • (2013) Immunity , vol.39 , pp. 1003-1018
    • Garlanda, C.1    Dinarello, C.A.2    Mantovani, A.3
  • 25
    • 65549097702 scopus 로고    scopus 로고
    • Interleukin-1beta augments angiogenic responses of murine endothelial progenitor cells in vitro
    • Rosell A., Arai K., Lok J., He T., Guo S., Navarro M., et al. Interleukin-1beta augments angiogenic responses of murine endothelial progenitor cells in vitro. J Cereb Blood Flow Metab 2009, 29:933-943.
    • (2009) J Cereb Blood Flow Metab , vol.29 , pp. 933-943
    • Rosell, A.1    Arai, K.2    Lok, J.3    He, T.4    Guo, S.5    Navarro, M.6
  • 26
    • 79955897768 scopus 로고    scopus 로고
    • Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions
    • 82ra38
    • Dombrowski Y., Peric M., Koglin S., Kammerbauer C., Goss C., Anz D., et al. Cytosolic DNA triggers inflammasome activation in keratinocytes in psoriatic lesions. Sci Transl Med 2011, 3:82ra38.
    • (2011) Sci Transl Med , vol.3
    • Dombrowski, Y.1    Peric, M.2    Koglin, S.3    Kammerbauer, C.4    Goss, C.5    Anz, D.6
  • 27
    • 34250835251 scopus 로고    scopus 로고
    • The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes
    • Feldmeyer L., Keller M., Niklaus G., Hohl D., Werner S., Beer H.D. The inflammasome mediates UVB-induced activation and secretion of interleukin-1beta by keratinocytes. Curr Biol 2007, 17:1140-1145.
    • (2007) Curr Biol , vol.17 , pp. 1140-1145
    • Feldmeyer, L.1    Keller, M.2    Niklaus, G.3    Hohl, D.4    Werner, S.5    Beer, H.D.6
  • 28
    • 67649831360 scopus 로고    scopus 로고
    • NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury
    • Yamasaki K., Muto J., Taylor K.R., Cogen A.L., Audish D., Bertin J., et al. NLRP3/cryopyrin is necessary for interleukin-1beta (IL-1beta) release in response to hyaluronan, an endogenous trigger of inflammation in response to injury. J Biol Chem 2009, 284:12762-12771.
    • (2009) J Biol Chem , vol.284 , pp. 12762-12771
    • Yamasaki, K.1    Muto, J.2    Taylor, K.R.3    Cogen, A.L.4    Audish, D.5    Bertin, J.6
  • 29
    • 1842581655 scopus 로고    scopus 로고
    • A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release
    • Elssner A., Duncan M., Gavrilin M., Wewers M.D. A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release. J Immunol 2004, 172:4987-4994.
    • (2004) J Immunol , vol.172 , pp. 4987-4994
    • Elssner, A.1    Duncan, M.2    Gavrilin, M.3    Wewers, M.D.4
  • 30
    • 57649213537 scopus 로고    scopus 로고
    • The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner
    • Tomasinsig L., Pizzirani C., Skerlavaj B., Pellegatti P., Gulinelli S., Tossi A., et al. The human cathelicidin LL-37 modulates the activities of the P2X7 receptor in a structure-dependent manner. J Biol Chem 2008, 283:30471-30481.
    • (2008) J Biol Chem , vol.283 , pp. 30471-30481
    • Tomasinsig, L.1    Pizzirani, C.2    Skerlavaj, B.3    Pellegatti, P.4    Gulinelli, S.5    Tossi, A.6
  • 32
    • 80955139264 scopus 로고    scopus 로고
    • The cutaneous vascular system in chronic skin inflammation
    • Huggenberger R., Detmar M. The cutaneous vascular system in chronic skin inflammation. J Investig Dermatol Symp Proc 2011, 15:24-32.
    • (2011) J Investig Dermatol Symp Proc , vol.15 , pp. 24-32
    • Huggenberger, R.1    Detmar, M.2
  • 33
    • 80052721418 scopus 로고    scopus 로고
    • Epidemiology of rosacea: updated data
    • Chosidow O., Cribier B. Epidemiology of rosacea: updated data. Ann Dermatol Venereol 2011, 138(Suppl 3):S179-S183.
    • (2011) Ann Dermatol Venereol , vol.138 , pp. S179-S183
    • Chosidow, O.1    Cribier, B.2
  • 34
    • 34648830374 scopus 로고    scopus 로고
    • Lymphangiogenesis and angiogenesis in non-phymatous rosacea
    • Gomaa A.H., Yaar M., Eyada M.M., Bhawan J. Lymphangiogenesis and angiogenesis in non-phymatous rosacea. J Cutan Pathol 2007, 34:748-753.
    • (2007) J Cutan Pathol , vol.34 , pp. 748-753
    • Gomaa, A.H.1    Yaar, M.2    Eyada, M.M.3    Bhawan, J.4
  • 35
    • 84860353132 scopus 로고    scopus 로고
    • Advances in understanding and managing rosacea: Part 1: Connecting the dots between pathophysiological mechanisms and common clinical features of rosacea with emphasis on vascular changes and facial erythema
    • Del Rosso J.Q. Advances in understanding and managing rosacea: Part 1: Connecting the dots between pathophysiological mechanisms and common clinical features of rosacea with emphasis on vascular changes and facial erythema. J Clin Aesthet Dermatol 2012, 5:16-25.
    • (2012) J Clin Aesthet Dermatol , vol.5 , pp. 16-25
    • Del Rosso, J.Q.1
  • 38
    • 1942422683 scopus 로고    scopus 로고
    • Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release
    • Kahlenberg J.M., Dubyak G.R. Mechanisms of caspase-1 activation by P2X7 receptor-mediated K+ release. Am J Physiol Cell Physiol 2004, 286:C1100-C1108.
    • (2004) Am J Physiol Cell Physiol , vol.286 , pp. C1100-C1108
    • Kahlenberg, J.M.1    Dubyak, G.R.2
  • 39
    • 33846219970 scopus 로고    scopus 로고
    • Extracellular ATP has stimulatory effects on the expression and release of IL-6 via purinergic receptors in normal human epidermal keratinocytes
    • Inoue K., Hosoi J., Denda M. Extracellular ATP has stimulatory effects on the expression and release of IL-6 via purinergic receptors in normal human epidermal keratinocytes. J Invest Dermatol 2007, 127:362-371.
    • (2007) J Invest Dermatol , vol.127 , pp. 362-371
    • Inoue, K.1    Hosoi, J.2    Denda, M.3
  • 41
    • 84872723949 scopus 로고    scopus 로고
    • Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages
    • Kahlenberg J.M., Carmona-Rivera C., Smith C.K., Kaplan M.J. Neutrophil extracellular trap-associated protein activation of the NLRP3 inflammasome is enhanced in lupus macrophages. J Immunol 2013, 190:1217-1226.
    • (2013) J Immunol , vol.190 , pp. 1217-1226
    • Kahlenberg, J.M.1    Carmona-Rivera, C.2    Smith, C.K.3    Kaplan, M.J.4
  • 42
    • 33847080458 scopus 로고    scopus 로고
    • Stimulation of purinergic receptors modulates chemokine expression in human keratinocytes
    • Pastore S., Mascia F., Gulinelli S., Forchap S., Dattilo C., Adinolfi E., et al. Stimulation of purinergic receptors modulates chemokine expression in human keratinocytes. J Invest Dermatol 2007, 127:660-667.
    • (2007) J Invest Dermatol , vol.127 , pp. 660-667
    • Pastore, S.1    Mascia, F.2    Gulinelli, S.3    Forchap, S.4    Dattilo, C.5    Adinolfi, E.6
  • 43
    • 15244351683 scopus 로고    scopus 로고
    • Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage
    • Hirakawa S., Fujii S., Kajiya K., Yano K., Detmar M. Vascular endothelial growth factor promotes sensitivity to ultraviolet B-induced cutaneous photodamage. Blood 2005, 105:2392-2399.
    • (2005) Blood , vol.105 , pp. 2392-2399
    • Hirakawa, S.1    Fujii, S.2    Kajiya, K.3    Yano, K.4    Detmar, M.5


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