Altered protein expression profile associated with phenotypic changes in lung fibroblasts co-cultured with gold nanoparticle-treated small airway epithelial cells

Biomaterials

Volumn 39, Issue , 2015, Pages 31-38

  Ng, Cheng Teng ^a   Yung, Lin Yue Lanry ^b   Swa, Hannah Lee Foon ^c   Poh, Rebecca Wan Yan ^d   Gunaratne, Jayantha ^c   Bay, Boon Huat ^a  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^c INSTITUTE OF MOLECULAR AND CELL BIOLOGY   (Singapore)

^d CARL ZEISS SMT AG   (Germany)

Author keywords

AuNPs; Co culture; Nanotoxicology; Proteome profiling; SILAC based mass spectrometry

Indexed keywords

AMINO ACIDS; BIOLOGICAL ORGANS; CELL ADHESION; CELL CULTURE; CROSSTALK; FIBROBLASTS; GOLD; ION BEAMS; ISOTOPES; MASS SPECTROMETRY; METAL NANOPARTICLES; SCANNING ELECTRON MICROSCOPY;

AUNPS; COCULTURE; DOWN-REGULATED PROTEINS; FOCUSED ION BEAM-SCANNING ELECTRON MICROSCOPIES; NANOTOXICOLOGY; PROTEIN EXPRESSION PROFILES; PROTEOME PROFILING; STABLE-ISOTOPE LABELING;

PROTEINS;

AMINO ACID; CAVEOLIN 1; CRK ASSOCIATED SUBSTRATE PROTEIN; F ACTIN; GOLD NANOPARTICLE; PAXILLIN; PROTEOME; STABLE ISOTOPE; VINCULIN; GOLD; METAL NANOPARTICLE;

ARTICLE; CELL ADHESION; CELL CULTURE; COCULTURE; CONTROLLED STUDY; DOWN REGULATION; EPITHELIUM CELL; FETUS; HUMAN; HUMAN CELL; LUNG FIBROBLAST; MASS SPECTROMETRY; MORPHOLOGY; PHENOTYPE; PROTEIN EXPRESSION; PROTEOMICS; SCANNING ELECTRON MICROSCOPY; SMALL AIRWAY EPITHELIAL CELL; UPREGULATION; CELL LINE; CHEMISTRY; CONFOCAL MICROSCOPY; CYTOLOGY; DRUG EFFECTS; FIBROBLAST; LUNG; METABOLISM;

CELL ADHESION; CELL LINE; COCULTURE TECHNIQUES; EPITHELIAL CELLS; FIBROBLASTS; GOLD; HUMANS; LUNG; METAL NANOPARTICLES; MICROSCOPY, CONFOCAL; MICROSCOPY, ELECTRON, SCANNING;

EID: 84919488323     PISSN: 01429612     EISSN: 18785905     Source Type: Journal    
DOI: 10.1016/j.biomaterials.2014.10.063     Document Type: Article

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