Caveolin-1 Regulates Endothelial Adhesion of Lung Cancer Cells via Reactive Oxygen Species-Dependent Mechanism

PLoS ONE

Volumn 8, Issue 2, 2013, Pages

  Chanvorachote, Pithi ^a   Chunhacha, Preedakorn ^a  

^a CHULALONGKORN UNIVERSITY   (Thailand)

Author keywords

[No Author keywords available]

Indexed keywords

CAVEOLIN 1; HYDROGEN PEROXIDE; HYDROXYL RADICAL; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; SHORT HAIRPIN RNA; VASCULAR CELL ADHESION MOLECULE 1;

ARTICLE; CANCER CELL; CAVEOLA; CELL ACTIVITY; CELL ADHESION; CELL INTERACTION; CELL ISOLATION; CELL LEVEL; CONTROLLED STUDY; DOWN REGULATION; ENDOTHELIUM CELL; ENZYME ACTIVATION; ENZYME REPRESSION; HUMAN; HUMAN CELL; LUNG CANCER; MOLECULAR MECHANICS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM;

CAVEOLIN 1; CELL ADHESION; CELL LINE, TUMOR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; HYDROGEN PEROXIDE; HYDROXYL RADICAL; LUNG NEOPLASMS; MODELS, BIOLOGICAL; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; VASCULAR CELL ADHESION MOLECULE-1;

EID: 84874537511     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0057466     Document Type: Article

References (33)

1. Lavie Y, Fiucci G, Liscovitch M, (1998) Up-regulation of caveolae and caveolar constituents in multidrug-resistant cancer cells. J Biol Chem 273: 32380-32383.
2. Ho CC, Kuo SH, Huang PH, Huang HY, Yang CH, et al. (2007) Caveolin-1 expression is significantly associated with drug resistance and poor prognosis in advanced non-small cell lung cancer patients treated with gemcitabine-based chemotherapy. Lung Cancer 59: 105-110.
3. Tahir SA, Yang G, Ebara S, Timme TL, Satoh T, et al. (2001) Secreted caveolin-1 stimulates cell survival/clonal growth and contributes to metastasis in androgen insensitive prostate cancer. Cancer Research 61: 3882-3885.
4. Sunaga N, Miyajima K, Suzuki M, Sato M, White MA, et al. (2004) Different Roles for Caveolin-1 in the Development of Non-Small Cell Lung Cancer versus Small Cell Lung Cancer. Cancer Research 64: 4277-4285.
5. Sloan EK, Stanley KL, Anderson RL, (2004) Caveolin-1 inhibits breast cancer growth and metastasis. Oncogene 23(47): 7893.
6. Rungtabnapa P, Nimmannit U, Halim H, Rojanasakul Y, Chanvorachote P, (2011) Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation. Am J Physiol Cell Physiol 300: C235-C245.
7. Lloyd PG, Hardin CD, (2011) Caveolae in cancer: two sides of the same coin? Focus on "Hydrogen peroxide inhibits non-small cell lung cancer cell anoikis through the inhibition of caveolin-1 degradation". Am J Physiol Cell Physiol 300: C232-C234.
8. Chanvorachote P, Nimmannit U, Lu Y, Talbott S, Jiang BH, et al. (2009) Nitric oxide regulates lung carcinoma cell anoikis through inhibition of ubiquitin-proteasomal degradation of caveolin-1. J Biol Chem 284: 28476-28484.
9. Chunhacha P, Pongrakhananon V, Rojanasakul Y, Chanvorachote P, (2012) Caveolin-1 regulates Mcl-1 stability and anoikis in lung carcinoma cells. Am J Physiol Cell Physiol 302: C1284-C1292.
10. Loza-Coll MA, Perera S, Shi W, Filmus J, (2005) A transient increase in the activity of Src-family kinases induced by cell detachment delays anoikis intestinal epithelial cells. Oncogene 24: 1727-1737.
11. Luanpitpong S, Talbott SJ, Rojanasakul Y, Nimmannit U, Pongrakhananon V, et al. (2010) Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1. J Biol Chem 285: 38832-38840.
12. Halim H, Luanpitpong S, Chanvorachote P, (2012) Acquisition of anoikis resistance up-regulates caveolin-1 expression in human non-small cell lung cancer cells. Anticancer Res 32: 1649-1658.
13. Suchaoin W, Chanvorachote P, (2012) Caveolin-1 attenuates hydrogen peroxide induced oxidative damage to lung carcinoma cells. Anticancer Res 32: 483-490.
14. Tozawa K, Sakurada S, Kohri K, Okamoto T, (1995) Effects of anti-nuclear factor kB reagents in blocking adhesion of human cancer cells to vascular endothelial cells Cancer Research. 55: 4162-4167.
15. Kobayashi K, Matsumoto S, Morishima T, Kawabe T, Okamoto T, (2000) Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Research 60: 3978-3984.
16. Li L, Ren CH, Tahir SA, Ren C, Thompson TC, (2003) Caveolin-1 Maintains Activated Akt in prostate cancer cells through scaffolding domain binding site interactions with and inhibition of serine/threonine protein phosphatases PP1 and PP2A. Mol Cell Biol 23: 9389-9404.
17. Vazquez F, Ramaswamy S, Nakamura N, Sellers WR, (2000) Phosphorylation of the PTEN tail regulates protein stability and function. Mol Cell Biol 20: 5010-5018.
18. Dhanasekaran SM, Barrette TR, Ghosh D, Shah R, Varambally S, et al. (2001) Delineation of prognostic biomarkers in prostate cancer. Nature 412: 822-826.
19. Kobayashi H, Boelte KC, Lin PC, (2007) Endothelial cell adhesion molecules and cancer progression. Curr Med Chem 14: 377-386.
20. Williams TM, Lisanti MP, (2005) Caveolin-1 in oncogenic transformation, cancer, and metastasis. Am J Physiol Cell Physiol 288: 494-506.
21. Fiucci G, Ravid D, Reich R, Liscovitch M, (2002) Caveolin-1 inhibits anchorage-independent growth, anoikis and invasiveness in MCF-7 human breast cancer cells. Oncogene 21: 2365-2375.
22. Fra AM, Masserini M, Palestini P, Sonnino S, Simons K, (1995) A photoreactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface. FEBS Lett 375: 11-14.
23. Frisch SM, Francis H, (1994) Disruption of epithelial cell-matrix interactions induces apoptosis. J Cell Biol 124: 619-626.
24. Frisch SM, Screaton RA, (2001) Anoikis mechanisms. Curr Opin Cell Biol 13: 555-562.
25. Garcia-Cardena G, Oh P, Liu J, Schnitzer JE, Sessa WC, (1996) Targeting of nitric oxide synthase to endothelial cell caveolae via palmitoylation: implications for nitric oxide signaling. Proc Natl Acad Sci USA 93: 6448-6453.
26. Hampton MB, Orrenius S, (1997) Dual regulation of caspase activity by hydrogen peroxide: implications for apoptosis. FEBS Lett 414: 552-556.
27. Hanahan D, Weinberg RA, (2000) The hallmarks of cancer. Cell 100: 57-70.
28. Hileman OE, Liu J, Albitar M, Keating MJ, Huang P, (2004) Intrinsic oxidative stress in cancer cells: a biochemical basis for therapeutic selectivity. Cancer Chemother Pharmacol 53: 209-219.
29. Suzuki K, Eguchi H, Koh YH, Park YS, Taniguchi N, (1999) Acceleration of adhesion of cancer cells and neutrophils to endothelial cells in the absence of de novo protein synthesis: possible implication for involvement of hydroxyl radicals. Biochem Biophys Res Commun 257: 214-217.
30. Chen Q, Massagué J, (2012) Molecular pathways: vcam-1 as a potential therapeutic target in metastasis. Clin Cancer Res 18: 5520-5525.
31. Newham P, Craig SE, Seddon GN, Schofield NR, Rees A, et al. (1997) Alpha4 integrin binding interfaces on VCAM-1 and MAdCAM-1. Integrin binding footprints identify accessory binding sites that play a role in integrin specificity. J Biol Chem 272: 19429-19440.
32. Georgescu MM, (2010) PTEN Tumor Suppressor Network in PI3K-Akt Pathway Control. Genes Cancer 1(12): 1170-1177.
33. Carnero A, Blanco-Aparicio C, Renner O, Link W, Leal JF, (2008) The PTEN/PI3K/AKT signaling pathway in cancer, therapeutic implications. Curr Cancer Drug Targets 8(3): 187-198.