Mesenchymal chemotaxis requires selective inactivation of Myosin II at the leading edge via a noncanonical PLCγ/PKCα pathway

Developmental Cell

Volumn 31, Issue 6, 2014, Pages 747-760

  Asokan, SreejaB ^a,c   Johnson, HeathE ^b   Rahman, Anisur ^b   King, SamanthaJ ^a   Rotty, JeremyD ^a,c   Lebedeva, IrinaP ^a,c   Haugh, JasonM ^b   Bear, JamesE ^a,c  

^a UNIVERSITY OF NORTH CAROLINA SCHOOL OF MEDICINE   (United States)

^b North Carolina State University   (United States)

^c UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIACYLGLYCEROL; MAMMALIAN TARGET OF RAPAMYCIN; MYOSIN IIA; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE PHOSPHODIESTERASE GAMMA; PLATELET DERIVED GROWTH FACTOR; PROTEIN KINASE C ALPHA; UNCLASSIFIED DRUG; GREEN FLUORESCENT PROTEIN; LIGAND; MYOSIN II; PHORBOL ESTER; PHOSPHOLIPASE C GAMMA;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL MIGRATION; CHEMOTAXIS; CONTROLLED STUDY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LIGHT CHAIN; MESENCHYME CELL; MICROFLUIDIC ANALYSIS; MOUSE; NONHUMAN; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; ANIMAL; CELL LINE; CELL MOTION; CHEMISTRY; MESODERM; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TRANSGENIC MOUSE;

MAMMALIA;

ANIMALS; CELL LINE; CELL MOVEMENT; CHEMOTAXIS; DIGLYCERIDES; GREEN FLUORESCENT PROTEINS; HUMANS; LIGANDS; MESODERM; MICE; MICE, TRANSGENIC; MYOSIN TYPE II; PHORBOL ESTERS; PHOSPHOLIPASE C GAMMA; PHOSPHORYLATION; PLATELET-DERIVED GROWTH FACTOR; PROTEIN KINASE C-ALPHA; SIGNAL TRANSDUCTION;

EID: 84919482922     PISSN: 15345807     EISSN: 18781551     Source Type: Journal    
DOI: 10.1016/j.devcel.2014.10.024     Document Type: Article

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