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Volumn 43, Issue , 2015, Pages 11-16

Inflammatory profiles in the BTBR mouse: HOW relevant are they to autism spectrum disorders?

Author keywords

ASD; Autism; BTBR; Immune; Inflammation; Model; Mouse

Indexed keywords

ANIMAL MODEL; AUTISM; COMPULSION; ENVIRONMENTAL FACTOR; EXECUTIVE FUNCTION; FACE VALIDITY; HEREDITY; IMMUNE DYSREGULATION; INFLAMMATORY DISEASE; INNATE IMMUNITY; INSTRUMENTAL CONDITIONING; MOUSE; NONHUMAN; PHENOTYPE; REVIEW; SOCIAL BEHAVIOR; SPATIAL LEARNING; TASK PERFORMANCE; ANIMAL; DISEASE MODEL; HUMAN RELATION; IMMUNOLOGY; INBRED MOUSE STRAIN; INFLAMMATION;

EID: 84919462056     PISSN: 08891591     EISSN: 10902139     Source Type: Journal    
DOI: 10.1016/j.bbi.2014.06.006     Document Type: Review
Times cited : (63)

References (64)
  • 1
    • 81255163675 scopus 로고    scopus 로고
    • Differences in BTBR T+ tf/J and C57BL/6J mice on probabilistic reversal learning and stereotyped behaviors
    • Amodeo D.A., Jones J.H., Sweeney J.A., Ragozzino M.E. Differences in BTBR T+ tf/J and C57BL/6J mice on probabilistic reversal learning and stereotyped behaviors. Behav. Brain Res. 2012, 227:64-72.
    • (2012) Behav. Brain Res. , vol.227 , pp. 64-72
    • Amodeo, D.A.1    Jones, J.H.2    Sweeney, J.A.3    Ragozzino, M.E.4
  • 2
    • 0003472502 scopus 로고    scopus 로고
    • Diagnostic and Statistical Manual of Mental Disorders
    • A.P.A. (Ed.), fifth ed.
    • APA. In: A.P.A. (Ed.), Diagnostic and Statistical Manual of Mental Disorders, fifth ed., 2013.
    • (2013)
  • 3
    • 78649322790 scopus 로고    scopus 로고
    • Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
    • Ashwood P., Krakowiak P., Hertz-Picciotto I., Hansen R., Pessah I., Van de Water J. Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome. Brain Behav. Immun. 2011, 25:40-45.
    • (2011) Brain Behav. Immun. , vol.25 , pp. 40-45
    • Ashwood, P.1    Krakowiak, P.2    Hertz-Picciotto, I.3    Hansen, R.4    Pessah, I.5    Van de Water, J.6
  • 5
    • 33751581761 scopus 로고    scopus 로고
    • The immune response in autism: a new frontier for autism research
    • Ashwood P., Wills S., Van de Water J. The immune response in autism: a new frontier for autism research. J. Leukoc. Biol. 2006, 80:1-15.
    • (2006) J. Leukoc. Biol. , vol.80 , pp. 1-15
    • Ashwood, P.1    Wills, S.2    Van de Water, J.3
  • 6
    • 58149347325 scopus 로고    scopus 로고
    • Exaggerated responses to stress in the BTBR T+tf/J mouse: an unusual behavioral phenotype
    • Benno R., Smirnova Y., Vera S., Liggett A., Schanz N. Exaggerated responses to stress in the BTBR T+tf/J mouse: an unusual behavioral phenotype. Behav. Brain Res. 2009, 197:462-465.
    • (2009) Behav. Brain Res. , vol.197 , pp. 462-465
    • Benno, R.1    Smirnova, Y.2    Vera, S.3    Liggett, A.4    Schanz, N.5
  • 7
    • 0028025030 scopus 로고
    • A novel automated touchscreen procedure for assessing learning in the rat using computer graphic stimuli
    • Bussey T.J., Muir J.L., Robbins T.W. A novel automated touchscreen procedure for assessing learning in the rat using computer graphic stimuli. Neurosci. Res. Commun. 1994, 15:103-110.
    • (1994) Neurosci. Res. Commun. , vol.15 , pp. 103-110
    • Bussey, T.J.1    Muir, J.L.2    Robbins, T.W.3
  • 9
    • 84859394070 scopus 로고    scopus 로고
    • Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. Morbidity and mortality weekly report
    • CDC Prevalence of autism spectrum disorders - Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2008. Morbidity and mortality weekly report. Surveill. Summ. 2012, 61:1-19.
    • (2012) Surveill. Summ. , vol.61 , pp. 1-19
  • 12
    • 78650414129 scopus 로고    scopus 로고
    • A novel social proximity test suggests patterns of social avoidance and gaze aversion-like behavior in BTBR T+ tf/J mice
    • Defensor E.B., Pearson B.L., Pobbe R.L., Bolivar V.J., Blanchard D.C., Blanchard R.J. A novel social proximity test suggests patterns of social avoidance and gaze aversion-like behavior in BTBR T+ tf/J mice. Behav. Brain Res. 2011, 217:302-308.
    • (2011) Behav. Brain Res. , vol.217 , pp. 302-308
    • Defensor, E.B.1    Pearson, B.L.2    Pobbe, R.L.3    Bolivar, V.J.4    Blanchard, D.C.5    Blanchard, R.J.6
  • 15
    • 71749094505 scopus 로고    scopus 로고
    • Differential monocyte responses to TLR ligands in children with autism spectrum disorders
    • Enstrom A.M., Onore C.E., Van de Water J.A., Ashwood P. Differential monocyte responses to TLR ligands in children with autism spectrum disorders. Brain Behav. Immun. 2010, 24:64-71.
    • (2010) Brain Behav. Immun. , vol.24 , pp. 64-71
    • Enstrom, A.M.1    Onore, C.E.2    Van de Water, J.A.3    Ashwood, P.4
  • 16
    • 84882282383 scopus 로고    scopus 로고
    • Evidence for a dysregulated immune system in the etiology of psychiatric disorders
    • Gibney S.M., Drexhage H.A. Evidence for a dysregulated immune system in the etiology of psychiatric disorders. J. Neuroimmune Pharmacol. 2013, 8:900-920.
    • (2013) J. Neuroimmune Pharmacol. , vol.8 , pp. 900-920
    • Gibney, S.M.1    Drexhage, H.A.2
  • 17
    • 84885661909 scopus 로고    scopus 로고
    • Gestational exposure to a viral mimetic poly(i:C) results in long-lasting changes in mitochondrial function by leucocytes in the adult offspring
    • Giulivi C., Napoli E., Schwartzer J., Careaga M., Ashwood P. Gestational exposure to a viral mimetic poly(i:C) results in long-lasting changes in mitochondrial function by leucocytes in the adult offspring. Mediators Inflamm. 2013, 2013:609602.
    • (2013) Mediators Inflamm. , vol.2013 , pp. 609602
    • Giulivi, C.1    Napoli, E.2    Schwartzer, J.3    Careaga, M.4    Ashwood, P.5
  • 19
    • 84884256116 scopus 로고    scopus 로고
    • Water T-maze: a useful assay for determination of repetitive behaviors in mice
    • Guariglia S.R., Chadman K.K. Water T-maze: a useful assay for determination of repetitive behaviors in mice. J. Neurosci. Methods 2013, 220:24-29.
    • (2013) J. Neurosci. Methods , vol.220 , pp. 24-29
    • Guariglia, S.R.1    Chadman, K.K.2
  • 21
    • 79960574244 scopus 로고    scopus 로고
    • Aberrant immune responses in a mouse with behavioral disorders
    • Heo Y., Zhang Y., Gao D., Miller V.M., Lawrence D.A. Aberrant immune responses in a mouse with behavioral disorders. PLoS One 2011, 6:e20912.
    • (2011) PLoS One , vol.6 , pp. e20912
    • Heo, Y.1    Zhang, Y.2    Gao, D.3    Miller, V.M.4    Lawrence, D.A.5
  • 25
    • 15244348759 scopus 로고    scopus 로고
    • Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism
    • James S.J., Cutler P., Melnyk S., Jernigan S., Janak L., Gaylor D.W., Neubrander J.A. Metabolic biomarkers of increased oxidative stress and impaired methylation capacity in children with autism. Am. J. Clin. Nutr. 2004, 80:1611-1617.
    • (2004) Am. J. Clin. Nutr. , vol.80 , pp. 1611-1617
    • James, S.J.1    Cutler, P.2    Melnyk, S.3    Jernigan, S.4    Janak, L.5    Gaylor, D.W.6    Neubrander, J.A.7
  • 26
    • 58549083388 scopus 로고    scopus 로고
    • Impact of innate immunity in a subset of children with autism spectrum disorders: a case control study
    • Jyonouchi H., Geng L., Cushing-Ruby A., Quraishi H. Impact of innate immunity in a subset of children with autism spectrum disorders: a case control study. J. Neuroinflammation 2008, 5:52.
    • (2008) J. Neuroinflammation , vol.5 , pp. 52
    • Jyonouchi, H.1    Geng, L.2    Cushing-Ruby, A.3    Quraishi, H.4
  • 27
    • 80052864423 scopus 로고    scopus 로고
    • Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes
    • Jyonouchi H., Geng L., Streck D.L., Toruner G.A. Children with autism spectrum disorders (ASD) who exhibit chronic gastrointestinal (GI) symptoms and marked fluctuation of behavioral symptoms exhibit distinct innate immune abnormalities and transcriptional profiles of peripheral blood (PB) monocytes. J. Neuroimmunol. 2011, 238:73-80.
    • (2011) J. Neuroimmunol. , vol.238 , pp. 73-80
    • Jyonouchi, H.1    Geng, L.2    Streck, D.L.3    Toruner, G.A.4
  • 28
    • 0034750434 scopus 로고    scopus 로고
    • Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression
    • Jyonouchi H., Sun S., Le H. Proinflammatory and regulatory cytokine production associated with innate and adaptive immune responses in children with autism spectrum disorders and developmental regression. J. Neuroimmunol. 2001, 120:170-179.
    • (2001) J. Neuroimmunol. , vol.120 , pp. 170-179
    • Jyonouchi, H.1    Sun, S.2    Le, H.3
  • 29
    • 84862275332 scopus 로고    scopus 로고
    • Systematic autistic-like behavioral phenotyping of 4 mouse strains using a novel wheel-running assay
    • Karvat G., Kimchi T. Systematic autistic-like behavioral phenotyping of 4 mouse strains using a novel wheel-running assay. Behav. Brain Res. 2012, 233:405-414.
    • (2012) Behav. Brain Res. , vol.233 , pp. 405-414
    • Karvat, G.1    Kimchi, T.2
  • 33
    • 84876542834 scopus 로고    scopus 로고
    • The BTBR mouse model of autism spectrum disorders has learning and attentional impairments and alterations in acetylcholine and kynurenic acid in prefrontal cortex
    • McTighe S.M., Neal S.J., Lin Q., Hughes Z.A., Smith D.G. The BTBR mouse model of autism spectrum disorders has learning and attentional impairments and alterations in acetylcholine and kynurenic acid in prefrontal cortex. PLoS One 2013, 8:e62189.
    • (2013) PLoS One , vol.8 , pp. e62189
    • McTighe, S.M.1    Neal, S.J.2    Lin, Q.3    Hughes, Z.A.4    Smith, D.G.5
  • 34
    • 79954578712 scopus 로고    scopus 로고
    • Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation?
    • Meyer U., Feldon J., Dammann O. Schizophrenia and autism: both shared and disorder-specific pathogenesis via perinatal inflammation?. Pediatr. Res. 2011, 69:26R-33R.
    • (2011) Pediatr. Res. , vol.69 , pp. 26R-33R
    • Meyer, U.1    Feldon, J.2    Dammann, O.3
  • 37
    • 84857190395 scopus 로고    scopus 로고
    • The role of immune dysfunction in the pathophysiology of autism
    • Onore C., Careaga M., Ashwood P. The role of immune dysfunction in the pathophysiology of autism. Brain Behav. Immun. 2012, 26:383-392.
    • (2012) Brain Behav. Immun. , vol.26 , pp. 383-392
    • Onore, C.1    Careaga, M.2    Ashwood, P.3
  • 40
    • 84861551676 scopus 로고    scopus 로고
    • Absence of social conditioned place preference in BTBR T+tf/J mice: relevance for social motivation testing in rodent models of autism
    • Pearson B.L., Bettis J.K., Meyza K.Z., Yamamoto L.Y., Blanchard D.C., Blanchard R.J. Absence of social conditioned place preference in BTBR T+tf/J mice: relevance for social motivation testing in rodent models of autism. Behav. Brain Res. 2012, 233:99-104.
    • (2012) Behav. Brain Res. , vol.233 , pp. 99-104
    • Pearson, B.L.1    Bettis, J.K.2    Meyza, K.Z.3    Yamamoto, L.Y.4    Blanchard, D.C.5    Blanchard, R.J.6
  • 45
    • 78149407237 scopus 로고    scopus 로고
    • Female urine-induced male mice ultrasonic vocalizations, but not scent-marking, is modulated by social experience
    • Roullet F.I., Wohr M., Crawley J.N. Female urine-induced male mice ultrasonic vocalizations, but not scent-marking, is modulated by social experience. Behav. Brain Res. 2011, 216:19-28.
    • (2011) Behav. Brain Res. , vol.216 , pp. 19-28
    • Roullet, F.I.1    Wohr, M.2    Crawley, J.N.3
  • 46
    • 84863435952 scopus 로고    scopus 로고
    • Intact and impaired executive abilities in the BTBR mouse model of autism
    • Rutz H.L., Rothblat L.A. Intact and impaired executive abilities in the BTBR mouse model of autism. Behav. Brain Res. 2012, 234:33-37.
    • (2012) Behav. Brain Res. , vol.234 , pp. 33-37
    • Rutz, H.L.1    Rothblat, L.A.2
  • 47
    • 52449086931 scopus 로고    scopus 로고
    • Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism
    • Scattoni M.L., Gandhy S.U., Ricceri L., Crawley J.N. Unusual repertoire of vocalizations in the BTBR T+tf/J mouse model of autism. PLoS One 2008, 3:e3067.
    • (2008) PLoS One , vol.3 , pp. e3067
    • Scattoni, M.L.1    Gandhy, S.U.2    Ricceri, L.3    Crawley, J.N.4
  • 48
    • 84880326713 scopus 로고    scopus 로고
    • Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+ tf/J strain, a mouse model of autism
    • Scattoni M.L., Martire A., Cartocci G., Ferrante A., Ricceri L. Reduced social interaction, behavioural flexibility and BDNF signalling in the BTBR T+ tf/J strain, a mouse model of autism. Behav. Brain Res. 2013, 251:35-40.
    • (2013) Behav. Brain Res. , vol.251 , pp. 35-40
    • Scattoni, M.L.1    Martire, A.2    Cartocci, G.3    Ferrante, A.4    Ricceri, L.5
  • 49
    • 84875139890 scopus 로고    scopus 로고
    • Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice
    • Schwartzer J.J., Careaga M., Onore C.E., Rushakoff J.A., Berman R.F., Ashwood P. Maternal immune activation and strain specific interactions in the development of autism-like behaviors in mice. Transl. Psychiatry 2013, 3:e240.
    • (2013) Transl. Psychiatry , vol.3 , pp. e240
    • Schwartzer, J.J.1    Careaga, M.2    Onore, C.E.3    Rushakoff, J.A.4    Berman, R.F.5    Ashwood, P.6
  • 50
    • 84857883847 scopus 로고    scopus 로고
    • Macrophage plasticity and polarization: in vivo veritas
    • Sica A., Mantovani A. Macrophage plasticity and polarization: in vivo veritas. J. Clin. Invest. 2012, 122:787-795.
    • (2012) J. Clin. Invest. , vol.122 , pp. 787-795
    • Sica, A.1    Mantovani, A.2
  • 53
    • 0029946317 scopus 로고    scopus 로고
    • Plasma increase of interleukin-12 and interferon-gamma. Pathological significance in autism
    • Singh V.K. Plasma increase of interleukin-12 and interferon-gamma. Pathological significance in autism. J. Neuroimmunol. 1996, 66:143-145.
    • (1996) J. Neuroimmunol. , vol.66 , pp. 143-145
    • Singh, V.K.1
  • 54
    • 79953748372 scopus 로고    scopus 로고
    • Probabilistic reinforcement learning in adults with autism spectrum disorders
    • Solomon M., Smith A.C., Frank M.J., Ly S., Carter C.S. Probabilistic reinforcement learning in adults with autism spectrum disorders. Autism Res. 2011, 4:109-120.
    • (2011) Autism Res. , vol.4 , pp. 109-120
    • Solomon, M.1    Smith, A.C.2    Frank, M.J.3    Ly, S.4    Carter, C.S.5
  • 57
    • 67349201064 scopus 로고    scopus 로고
    • Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety
    • Thomas A., Burant A., Bui N., Graham D., Yuva-Paylor L.A., Paylor R. Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety. Psychopharmacology 2009, 204:361-373.
    • (2009) Psychopharmacology , vol.204 , pp. 361-373
    • Thomas, A.1    Burant, A.2    Bui, N.3    Graham, D.4    Yuva-Paylor, L.A.5    Paylor, R.6
  • 58
  • 59
    • 0037414416 scopus 로고    scopus 로고
    • Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum
    • Wahlsten D., Metten P., Crabbe J.C. Survey of 21 inbred mouse strains in two laboratories reveals that BTBR T/+ tf/tf has severely reduced hippocampal commissure and absent corpus callosum. Brain Res. 2003, 971:47-54.
    • (2003) Brain Res. , vol.971 , pp. 47-54
    • Wahlsten, D.1    Metten, P.2    Crabbe, J.C.3
  • 60
    • 78751697098 scopus 로고    scopus 로고
    • Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism
    • Wohr M., Roullet F.I., Crawley J.N. Reduced scent marking and ultrasonic vocalizations in the BTBR T+tf/J mouse model of autism. Genes Brain Behav. 2011, 10:35-43.
    • (2011) Genes Brain Behav. , vol.10 , pp. 35-43
    • Wohr, M.1    Roullet, F.I.2    Crawley, J.N.3
  • 61
    • 84887883709 scopus 로고    scopus 로고
    • Male mice emit distinct ultrasonic vocalizations when the female leaves the social interaction arena
    • Yang M., Loureiro D., Kalikhman D., Crawley J.N. Male mice emit distinct ultrasonic vocalizations when the female leaves the social interaction arena. Front. Behav. Neurosci. 2013, 7:159.
    • (2013) Front. Behav. Neurosci. , vol.7 , pp. 159
    • Yang, M.1    Loureiro, D.2    Kalikhman, D.3    Crawley, J.N.4
  • 62
    • 79951562741 scopus 로고    scopus 로고
    • Social peers rescue autism-relevant sociability deficits in adolescent mice
    • Yang M., Perry K., Weber M.D., Katz A.M., Crawley J.N. Social peers rescue autism-relevant sociability deficits in adolescent mice. Autism Res. 2011, 4:17-27.
    • (2011) Autism Res. , vol.4 , pp. 17-27
    • Yang, M.1    Perry, K.2    Weber, M.D.3    Katz, A.M.4    Crawley, J.N.5
  • 63
    • 36549077053 scopus 로고    scopus 로고
    • Social deficits in BTBR T+tf/J mice are unchanged by cross-fostering with C57BL/6J mothers
    • Yang M., Zhodzishsky V., Crawley J.N. Social deficits in BTBR T+tf/J mice are unchanged by cross-fostering with C57BL/6J mothers. Int. J. Dev. Neurosci. 2007, 25:515-521.
    • (2007) Int. J. Dev. Neurosci. , vol.25 , pp. 515-521
    • Yang, M.1    Zhodzishsky, V.2    Crawley, J.N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.