Massive autophosphorylation of the Ser/Thr-rich domain controls protein kinase activity of TRPM6 and TRPM7

PLoS ONE

Volumn 3, Issue 3, 2008, Pages

  Clark, Kristopher ^a   Middelbeek, Jeroen ^a   Morrice, Nick A ^b   Figdor, Carl G ^a   Lasonder, Edwin ^a   van Leeuwen, Frank N ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

MYOSIN II; PROTEIN SERINE THREONINE KINASE; TRANSIENT RECEPTOR POTENTIAL CHANNEL M; TRANSIENT RECEPTOR POTENTIAL CHANNEL M6; TRANSIENT RECEPTOR POTENTIAL CHANNEL M7; PROTEIN KINASE; SERINE; THREONINE; TRPM6 PROTEIN, HUMAN; TRPM7 PROTEIN, HUMAN;

AMINO TERMINAL SEQUENCE; ARTICLE; AUTOPHOSPHORYLATION; CARBOXY TERMINAL SEQUENCE; CELL STRAIN HEK293; CHANNEL GATING; CONTROLLED STUDY; CYTOSOL; ELECTROPHORETIC MOBILITY; EMBRYO; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; ENZYME SUBSTRATE; GENE DELETION; GENE SEQUENCE; GENETIC CONSERVATION; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; MOLECULAR RECOGNITION; POLYACRYLAMIDE GEL ELECTROPHORESIS; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN INTERACTION; TANDEM MASS SPECTROMETRY; CATALYSIS; CELL LINE; CHEMISTRY; GENETICS; METABOLISM; PHOSPHORYLATION; SITE DIRECTED MUTAGENESIS;

CATALYSIS; CELL LINE; HUMANS; MUTAGENESIS, SITE-DIRECTED; MYOSIN TYPE II; PHOSPHORYLATION; PROTEIN KINASES; SEQUENCE DELETION; SERINE; THREONINE; TRPM CATION CHANNELS;

EID: 46749143291     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0001876     Document Type: Article

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