Development of an antifungal denture adhesive film for oral candidiasis utilizing hot melt extrusion technology

Expert Opinion on Drug Delivery

Volumn 12, Issue 1, 2015, Pages 1-13

  Park, Jun Bom ^a   Prodduturi, Suneela ^a   Morott, Joe ^a   Kulkarni, Vijay I ^a   Jacob, Melissa R ^b   Khan, Shabana I ^b   Stodghill, Steven P ^c   Repka, Michael A ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b UNIVERSITY OF MISSISSIPPI   (United States)

^c BELMONT UNIVERSITY   (United States)

Author keywords

Bioadhesive film; Hot melt extrusion; Hydroxypropyl cellulose; Oral candidiasis; Polyethylene oxide

Indexed keywords

ADHESIVE AGENT; AMPHOTERICIN B; ANTIFUNGAL AGENT; CLOTRIMAZOLE; HYDROXYPROPYLCELLULOSE; MACROGOL; NYSTATIN; CELLULOSE; MACROGOL DERIVATIVE;

ANTIFUNGAL ACTIVITY; ANTIFUNGAL DENTURE ADHESIVE FILM SYSTEM; ARTICLE; CANDIDA ALBICANS; CELL ADHESION; CONCENTRATION RESPONSE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DENTURE; DIFFERENTIAL SCANNING CALORIMETRY; DRUG MANUFACTURE; DRUG STABILITY; HOT MELT EXTRUSION; HUMAN; IC50; MAMMAL CELL; MANDIBLE; MAXILLA; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; THRUSH; VERO CELL LINE; VISCOSITY; X RAY POWDER DIFFRACTION; ANALOGS AND DERIVATIVES; ANIMAL; CANDIDIASIS, ORAL; CHEMISTRY; MEDICINAL CHEMISTRY; MICROBIAL SENSITIVITY TEST; X RAY DIFFRACTION;

ADHESIVES; ANIMALS; ANTIFUNGAL AGENTS; CALORIMETRY, DIFFERENTIAL SCANNING; CANDIDIASIS, ORAL; CELLULOSE; CHEMISTRY, PHARMACEUTICAL; CLOTRIMAZOLE; DENTURES; MICROBIAL SENSITIVITY TESTS; NYSTATIN; POLYETHYLENE GLYCOLS; X-RAY DIFFRACTION;

EID: 84919442858     PISSN: 17425247     EISSN: 17447593     Source Type: Journal    
DOI: 10.1517/17425247.2014.949235     Document Type: Article

References (50)

1. Puel A, Cypowyj S, Bustamante J, et al. Chronic mucocutaneous candidiasis in humans with inborn errors of interleukin-17 immunity. Science 2011;332(6025):65-8
2. Vazquez JA. Options for the management of mucosal candidiasis in patients with AIDS and HIV infection. Pharmacotherapy 1999;19(1):76-87
3. IMS. Data on oral and pharyngeal candidiasis. IMS America, Danbury, CT, USA; 2009
4. Abu-Elteen K, Abu-Alteen R. The prevalence of Candida albicans populations in the mouths of complete denture wearers. New Microbiol 1998;21(1):41-8
5. Epstein JB, Polsky B. Oropharyngeal candidiasis: a review of its clinical spectrum and current therapies. Clin Ther 1998;20(1):40-57.
6. Sharon V, Fazel N. Oral candidiasis and angular cheilitis. Dermatol Ther 2010;23(3):230-42
7. Mason KL, Downward JRE, Mason KD, et al. Candida albicans and bacterial microbiota interactions in the cecum during recolonization following broad-spectrum antibiotic therapy. Infect Immun 2012;80(10):3371-80
8. Morales DK, Hogan DA. Candida albicans interactions with bacteria in the context of human health and disease. PLoS Pathog 2010;6(4):e1000886
9. Rao PK. Oral candidiasis-A review. Biol Biomed Rep 2012;2(2):110-14.
10. Ramesh D, Reddy KJ. Evaluation of clinical efficacy of fluconazole mouth rinse for treatment of oral candidiasis. Ann Essences Dent 2010;2(4):10-14
11. Singh N, Nayyar A, Bhattacharjee G, et al. Assessment of dentifrices against Candida biofilm. Appl Biochem Biotechnol 2012;167(6):1688-98
12. Liguori G, Di Onofrio V, Lucariello A, et al. Oral candidiasis: a comparison between conventional methods and multiplex polymerase chain reaction for species identification. Oral Microbiol Immunol 2009;24(1):76-8
13. Alsterholm M. Studies on colonization and infection with Staphylococcus aureus and other microbes in skin disease. Sahlgrenska Academy at the University of Gothenburg, Sweden; 2012
14. Vazquez JA, Patton LL, Epstein JB, et al. Randomized, comparative, double-blind, double-dummy, multicenter trial of miconazole buccal tablet and clotrimazole troches for the treatment of oropharyngeal candidiasis: study of miconazole Lauriad- efficacy and safety (SMiLES). HIV Clin Trials 2010;11(4):186-96
15. Llabot J, Palma S, Manzo R, et al. Design of novel antifungal mucoadhesive films: Part II. Formulation and in vitro biopharmaceutical evaluation. Int J Pharm 2007;336(2):263-8.
16. Khana R, Agarwal S, Ahuja A. Preparation and evaluation of mucoadhesive buccal films of clotrimazole for oral Candida infections. Indian J Pharm Sci 1997;59(6):299
17. Deng W, Majumdar S, Singh A, et al. Stabilization of fenofibrate in low molecular weight hydroxypropylcellulose matrices produced by hot-melt extrusion. Drug Dev Ind Pharm 2013;39(2):290-8
18. Palem CR, Kumar Battu S, Maddineni S, et al. Oral transmucosal delivery of domperidone from immediate release films produced via hot-melt extrusion technology. Pharm Dev Technol 2013;18(1):186-95
19. Park J-B, Kang C-Y, Kang W-S, et al. New investigation of distribution imaging and content uniformity of very low dose drugs using hot-melt extrusion method. Int J Pharm 2013;458(2):245-53
20. Repka MA. Hot-melt extrusion. Am Pharm Rev 2009;12(6):18
21. Repka MA, Majumdar S, Kumar Battu S, et al. Applications of hot-melt extrusion for drug delivery. Expert Opin Drug Deliv 2008;5(12):1357-76.
22. Ali M, Afzal M, Bhattacharya SM, et al. Nanopharmaceuticals to target antifilarials: a comprehensive review. Expert Opin Drug Deliv 2013;10(5):665-78
23. Ariga K, Ji Q, Mori T, et al. Enzyme nanoarchitectonics: organization and device application. Chem Soc Rev 2013;42(15):6322-45
24. Wong BS, Yoong SL, Jagusiak A, et al. Carbon nanotubes for delivery of small molecule drugs. Adv Drug Deliv Rev 2013;65(15):1964-2015
25. Ariga K, Kawakami K, Hill JP. Emerging pressure-release materials for drug delivery. Expert Opin Drug Deliv 2013;10(11):1465-9
26. Repka MA, Prodduturi S, Stodghill SP. Production and characterization of hot-melt extruded films containing clotrimazole. Drug Dev Ind Pharm 2003;29(7):757-65
27. Azarmi S, Roa W, Lobenberg R. Current perspectives in dissolution testing of conventional and novel dosage forms. Int J Pharm 2007;328(1):12-21
28. Prodduturi S, Urman KL, Otaigbe JU, et al. Stabilization of hot-melt extrusion formulations containing solid solutions using polymer blends. AAPS PharmSciTech 2007;8(2):152-61.
29. Shah AK, Wyandt CM, Stodghill SP. Physico chemical characterization of a novel anti-cancer agent and its comparison to Taxol. Drug Dev Ind Pharm 2013;39(1):89-101
30. Yun Chang J, Oh Y-K, Soo Kong H, et al. Prolonged antifungal effects of clotrimazole-containing mucoadhesive thermosensitive gels on vaginitis. J Control Release 2002;82(1):39-50
31. Heneedak HM, Salama I, Mostafa S, et al. HPLC and chemometric methods for the simultaneous determination of miconazole nitrate and nystatin. J Chromatogr Sci 2012;50(10):855-61
32. Winston PW, Bates DH. Saturated solutions for the control of humidity in biological research. Ecology 1960;41(1):232-7
33. Peh KK, Wong CF. Polymeric films as vehicle for buccal delivery: swelling, mechanical, and bioadhesive properties. J Pharm Pharm Sci 1999;2(2):53-61
34. Thirawong N, Nunthanid J, Puttipipatkhachorn S, et al. Mucoadhesive properties of various pectins on gastrointestinal mucosa: an in vitro evaluation using texture analyzer. Eur J Pharm Biopharm 2007;67(1):132-40
35. Prodduturi S, Manek RV, Kolling WM, et al. Solid-state stability and characterization of hot-melt extruded poly (ethylene oxide) films. J Pharm Sci 2005;94(10):2232-45.
36. Repka MA, Gutta K, Prodduturi S, et al. Characterization of cellulosic hot-melt extruded films containing lidocaine. Eur J Pharm Biopharm 2005;59(1):189-96
37. Nair AB, Kumria R, Harsha S, et al. In vitro techniques to evaluate buccal films. J Control Release 2013;166(1):10-21.
38. Pelletier R, Peter J, Antin C, et al. Emergence of resistance of Candida albicans to clotrimazole in human immunodeficiency virus-infected children: in vitro and clinical correlations. J Clin Microbiol 2000;38(4):1563-8
39. Carrillo-Munoz A, Quindos G, Tur C, et al. In-vitro antifungal activity of liposomal nystatin in comparison with nystatin, amphotericin B cholesteryl sulphate, liposomal amphotericin B, amphotericin B lipid complex, amphotericin B desoxycholate, fluconazole and itraconazole. J Antimicrob Chemother 1999;44(3):397-401
40. Kopcha M, Tojo KJ, Lordi NG. Evaluation of methodology for assessing release characteristics of thermosoftening vehicles. J Pharm Pharmacol 1990;42(11):745-51
41. Ritger PL, Peppas NA. A simple equation for description of solute release I. Fickian and non-Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs. J Control Release 1987;5(1):23-36
42. Tronchin G, Bouchara J, Annaix V, et al. Fungal cell adhesion molecules in Candida albicans. Eur J Epidemiol 1991;7(1):23-33
43. Andes D, Safdar N, Marchillo K, et al. Pharmacokinetic-pharmacodynamic comparison of amphotericin B (AMB) and two lipid-associated AMB preparations, liposomal AMB and AMB lipid complex, in murine candidiasis models. Antimicrob Agents Chemother 2006;50(2):674-84
44. Bakker-Woudenberg IA, Schiffelers RM, Storm G, et al. Long-circulating sterically stabilized liposomes in the treatment of infections. Methods Enzymol 2005;391:228-60
45. Janknegt R, de Marie S, Bakker-Woudenberg IA, et al. Liposomal and lipid formulations of amphotericin B. Clin Pharmacokinet 1992;23(4):279-91
46. Proffitt RT, Satorius A, Chiang S-M, et al. Pharmacology and toxicology of a liposomal formulation of amphotericin B (AmBisome) in rodents. J Antimicrob Chemother 1991;28(Suppl B):49-61
47. Bilensoy E, Rouf MA, Vural I, et al. Mucoadhesive, thermosensitive, prolonged-release vaginal gel for clotrimazole: beta-cyclodextrin complex. AAPS PharmSciTech 2006;7(2):54-60
48. Croy SR, Kwon GS. The effects of Pluronic block copolymers on the aggregation state of nystatin. J Control Release 2004;95(2):161-71
49. Saerens L, Dierickx L, Lenain B, et al. Raman spectroscopy for the in-line polymer-drug quantification and solid state characterization during a pharmaceutical hot-melt extrusion process. Eur J Pharm Biopharm 2011;77(1):158-63
50. Science P. Hot melt extrusion. Particle Science. Technical Brief 2011;3:1-2