Antioxidative and chemopreventive effects of Nephrolepis biserrata against carbon tetrachloride (CCl4)-induced oxidative stress and hepatic dysfunction in rats

Pharmaceutical Biology

Volumn 53, Issue 1, 2015, Pages 31-39

  Shah, Muhammad Dawood ^a   Gnanaraj, Charles ^a   Haque, Atm Emdadul ^b   Iqbal, Mohammad ^a  

^a UNIVERSITI MALAYSIA SABAH   (Malaysia)

^b UNIVERSITI KUALA LUMPUR   (Malaysia)

Author keywords

Antioxidant enzymes; Histopathology; Liver injury; Methanol extract; Oxidative stress; Total phenolic content

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; CARBON TETRACHLORIDE; CATALASE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GLUTATHIONE; GLUTATHIONE PEROXIDASE; GLUTATHIONE TRANSFERASE; LIVER PROTECTIVE AGENT; MALONALDEHYDE; NEPHROLEPIS BISERRATA EXTRACT; PHENOL DERIVATIVE; PLANT EXTRACT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE (PHOSPHATE) DEHYDROGENASE (QUINONE); UNCLASSIFIED DRUG; ANTIOXIDANT;

ALANINE AMINOTRANSFERASE BLOOD LEVEL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; DPPH RADICAL SCAVENGING ASSAY; DRUG DOSE COMPARISON; LIVER DYSFUNCTION; LIVER FATTY DEGENERATION; LIVER NECROSIS; LIVER PROTECTION; MALE; NEPHROLEPIS BISERRATA; NONHUMAN; OXIDATIVE STRESS; PLANT LEAF; RAT; SPRAGUE DAWLEY RAT; ANIMAL; CHEMISTRY; DRUG EFFECTS; DRUG-INDUCED LIVER INJURY; ISOLATION AND PURIFICATION; LIPID PEROXIDATION; LIVER; LIVER FUNCTION TEST; METABOLISM; ORAL DRUG ADMINISTRATION; PATHOLOGY; POLYPODIACEAE; RANDOMIZATION;

NEPHROLEPIDACEAE; NEPHROLEPIS BISERRATA; RATTUS;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; CARBON TETRACHLORIDE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG-INDUCED LIVER INJURY; LIPID PEROXIDATION; LIVER; LIVER FUNCTION TESTS; MALE; OXIDATIVE STRESS; PLANT EXTRACTS; PLANT LEAVES; POLYPODIACEAE; RANDOM ALLOCATION; RATS, SPRAGUE-DAWLEY;

EID: 84919441787     PISSN: 13880209     EISSN: 17445116     Source Type: Journal    
DOI: 10.3109/13880209.2014.909502     Document Type: Article

References (45)

1. Adesanoye OA, Farombi EO. (2010). Hepatoprotective effects of Vernonia amygdalin (Astereaceae) in rats treated with carbon tetrachloride. Exp Toxicol Pathol 62:197-206.
2. Athar M, Iqbal M. (1998). Ferric nitrilotriacetate promotes N-diethylnitrosoamine induced renal tumorigenesis in rat: Implications for the involvement of oxidative stress. Carcinogenesis 19:1133-9.
3. Benson AM, Hunkeler AJ, Talalay P. (1980). Increase of NADPH: quinone reductase activity by dietary antioxidants: Possible role in protection against carcinogenesis and toxicity. Proc Natl Acad Sci USA 77:5216-20.
4. Boonkerd T, Chantanaorrapint S, Khwaiphan W. (2008). Pteridophyte diversity in the tropical lowland rainforest of Khao Nan national park, Nakhon Si Thammarat province, Thailand. Nat Hist J Chulalongkorn Univ 8:83-97.
5. Buege JA, Aust SD. (1978). Microsomal lipid peroxidation. In: Packer L, ed. Methods in Enzymology, vol. 52. New Jersey: Academic Press, 302-10.
6. Carlberg I, Mannervik B. (1975). Glutathione reductase levels in rat brain. J Biol Chem 250:5475-80.
7. Claiborne A. (1985). Catalase activity. In: Green Wald RA, ed. CRC Handbook of Methods for Oxygen Radical Research. Florida: CRC Press, 283-4.
8. Clawson GA. (1989). Mechanisms of carbon tetrachloride hepatotoxicity. Pathol Immunopathol Res 8:104-12.
9. Christensen H. (1997). Uses of ferns in two indigenous communities in Sarawak, Malaysia. In: Johns RJ, ed. Holttum Memorial Volume. United Kingdom: The Royal Botanic Gardens, Kew, 177-92.
10. Dambach DM, Durham SK, Laskin JD, Laskin DL. (2006). Distinct roles of NFkappaB p50 in the regulation of acetaminophen-induced inflammatory mediator production and hepatotoxicity. Toxicol Appl Pharmacol 211:157-65.
11. Dhanasekaran M, Ignacimuthu S, Agastian P. (2009). Potential hepatoprotective activity of ononitol monohydrate isolated from Cassia tora L on carbon tetrachloride induced hepatotoxicity in Wistar rats. Phytomedicine 16:891-5.
12. Habig WH, Pabst MJ, Jokoby WB. (1974). Glutathione S-transferase: The first enzymatic step in mercapturic acid formation. J Biol Chem 249:7130-9.
13. Halliwell B, Gutteridge JMC. (2007). Free Radicals in Biology and Medicine. New York: Oxford University Press.
14. Hatano T, Kagawa H, Yasuhara T, Okuda T. (1988). Two new flavonoids and other constituents in licorice root: Their relative astringency and radical scavenging effects. Chem Pharm Bull 36: 1090-2097.
15. Hodgson EK, Fridovich I. (1975). The interaction of bovine erythrocyte superoxide dismutase with hydrogen peroxide: Inactivation of the enzyme. Biochemistry 14:5294-9.
16. Iqbal M, Giri U, Giri DK, et al. (1999a). Age-dependent renal accumulation of 4-hydroxy-2-nonenal (HN)-modified proteins following parenteral administration of ferric nitrilotriacetate commensurate with its differential toxicity: Implications for the involvement of HNE-protein adducts in oxidative stress and carcinogenesis. Arch Biochem Biophys 365:101-12.
17. Iqbal M, Sharma SD, Rahman A, et al. (1999b). Evidence that ferric nitrilotriacetate mediates oxidative stress by down-regulating DT-diaphorase activity: Implications for carcinogenesis. Cancer Lett 141: 151-7.
18. Iqbal M, Rezazadeh H, Ansar S, Athar M. (1998). Alpha-Tocopherol (vitamin-E) ameliorates ferric nitrilotriacetate (Fe-NTA)-dependent renal proliferative response and toxicity: Diminution of oxidative stress. Hum Exp Toxicol 17:163-71.
19. 4 induced liver damage. Biochem Biophys Res Commun 329: 991-5.
20. Jiofack T, Fokunang C, Kemeuze V, et al. (2008). Ethnobotany and phytopharmacopoea of the Southwest ethno ecological region of Cameroon. J Med Plants Res 8:197-206.
21. Jollow DJ, Mitchell JR, Zampagilone N, Gillette JR. (1974). Bromobenzene-induced liver necrosis: Protective role of glutathione and evidence for 3, 4-bromobenzene oxides as a hepatotoxic intermediate. Pharmacology 11:151-69.
22. 4 poisoning? J Free Radic Biol Med 28:838-45
23. Kartesz JT. (1999). Synthesis of the North American Flora. Version 1.0. Biota of North America Program, North Carolina Botanical Garden, Chapel Hill, in cooperation with The Nature Conservancy, Natural Resources Conservation Service, U.S.D.A., and the U.S. Fish and Wildlife Service, U.S.D.I.
24. Kono Y, Fridovich I. (1982). Superoxide radical inhibits catalase. J Biol Chem 257:5751-4.
25. Kulip J, Fan LN, Manshoor N, et al. (2010). Medicinal plants in Maliau Basin, Sabah, Malaysia. J Trop Biol Conserv 6:21-33.
26. Langeland KA. (2001). Natural Area Weeds: Distinguishing Native and Non-native "Boston Ferns" and "Sword Ferns" (Nephrolepis spp.). University of Florida: Publication SSAGR22, 3-6.
27. 4 induced oxidative damage in rats. Food Chem Toxicol 45:888-95.
28. Malan DF, Neuba DFR. (2011). Traditional practices and medicinal plants use during pregnancy by Anyi-Ndenye women (Eastern Côte d'Ivoire). Afr J Reprod Health 15:85-93.
29. Manna P, Sinha M, Sil PC. (2006). Aqueous extract of Terminalia arjuna prevents carbon tetrachloride induced hepatic and renal disorders. BMC Complement Altern Med 6:1-10.
30. Mansour MA. (2000). Protective effects of thymoquinone and desfer-rioxamine against hepatotoxicity of carbon tetrachloride in mice. Life Sci 66:2583-91.
31. Mohandas J, Marshall JJ, Duggin GG, et al. (1984). Differential distribution of glutathione and glutathione related enzymes in rabbit kidney: Possible implications in analgesic neuropathy. Cancer Res 44: 5086-91.
32. Noguchi T, Fong KL, Lai EK, et al. (1982). Specificity of a phenobarbital-induced cytochrome P450 for metabolism of carbon tetrachloride to the trichloromethyl radical. Biochem Pharmacol 31: 615-24.
33. Packer JE, Slater TF, Willson RL. (1978). Reactions of the carbon tetrachlonde-related peroxy free radical with amino acids: Pulse radiolysis evidence. Life Sci 23:2617-20.
34. Piggott AG. (1996). Ferns of Malaysia in Color. Kuala Lumpur: Tropical Press.
35. Pradeep HA, Khan S, Ravikumar K, et al. (2009). Hepatoprotective evaluation of Anogeissus latifolia: In vitro and in vivo studies. World J Gastroenterol 15:4816-22.
36. Raja S, Nazeer Ahamed KF, Kumar V, et al. (2007). Antioxidant effect of Cytisus scoparius against carbon tetrachloride treated liver injury in rats. J Ethnopharmacol 109:41-7.
37. Reitman S, Frankel S. (1957). Colorimetric method for the determination of serum oxaloacetic and glutamic pyruvic transaminases. Am J Clin Pathol 28:56-63.
38. Seifried HE, Anderson DE, Fisher EI, Milner JA. (2007). A review of the interaction among dietary antioxidants and reactive oxygen species. J Nutr Biochem 18:567-79.
39. Singh N, Kamath V, Narasimhamurthy K, Rajini PS. (2008). Protective effects of potato peel extract against carbon tetrachloride-induced liver injury in rats. Environ Toxicol Pharmacol 26:241-6.
40. Srivastava A, Shivanandappa T. (2010). Hepatoprotective effect of the root extract of Decalepis hamiltonii against carbon tetrachloride-induced oxidative stress in rats. Food Chem 118:411-17.
41. Szymonik-Lesiuk S, Czechowska G, Stryjecka-Zimmer M, et al. (2003). Catalase, superoxide dismutase, and glutathione peroxidase activities in various rat tissues after carbon tetrachloride intoxication. J Hepatobiliary Pancreat Surg 10:309-15.
42. Velioglu YS, Mazza G, GAO L, Oomah BD. (1998). Antioxidant activity and total phenolics in selected fruits, vegetables, and grain products. J Agric Food Chem 46:4113-17.
43. 4-induced liver damage. Food Chem Toxicol 42:609-17.
44. Wang L, Weller CL. (2006). Recent advances in extraction of nutraceuticals from plants. Trends Food Sci Tech 17:300-12.
45. Zaheer N, Tiwari KK, Krishnan PS. (1965). Exposure and solubilization of hepatic mitochondrial shunt dehydrogenase. Arch Biochem Biophys 109:646-8.