-
1
-
-
77950501364
-
Proton pump inhibitor-induced tumour cell death by inhibition of a detoxification mechanism
-
Fais S: Proton pump inhibitor-induced tumour cell death by inhibition of a detoxification mechanism. J Intern Med 267: 515-525, 2010.
-
(2010)
J Intern Med
, vol.267
, pp. 515-525
-
-
Fais, S.1
-
2
-
-
0025321011
-
The mechanism and structure of the gastric H, K-ATPase
-
Rabon EC and Reuben MA: The mechanism and structure of the gastric H, K-ATPase. Annu Rev Physiol 52: 321-344, 1990.
-
(1990)
Annu Rev Physiol
, vol.52
, pp. 321-344
-
-
Rabon, E.C.1
Reuben, M.A.2
-
3
-
-
33748638016
-
Review article: The clinical pharmacology of proton pump inhibitors
-
Sachs G, Shin JM and Howden CW: Review article: the clinical pharmacology of proton pump inhibitors. Aliment Pharmacol Ther 23 (Suppl 2): 2-8, 2006.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, Issue.SUPPL. 2
, pp. 2-8
-
-
Sachs, G.1
Shin, J.M.2
Howden, C.W.3
-
4
-
-
3042544378
-
Chemistry of covalent inhibition of the gastric (H +, K +)-ATPase by proton pump inhibitors
-
Shin JM, Cho YM and Sachs G: Chemistry of covalent inhibition of the gastric (H +, K +)-ATPase by proton pump inhibitors. J Am Chem Soc 126: 7800-7811, 2004.
-
(2004)
J Am Chem Soc
, vol.126
, pp. 7800-7811
-
-
Shin, J.M.1
Cho, Y.M.2
Sachs, G.3
-
5
-
-
33750840296
-
The chemically elegant proton pump inhibitors
-
Roche VF: The chemically elegant proton pump inhibitors. Am J Pharm Educ 70: 101, 2006.
-
(2006)
Am J Pharm Educ
, vol.70
, pp. 101
-
-
Roche, V.F.1
-
6
-
-
0038235670
-
Acid inhibition on the first day of dosing: Comparison of four proton pump inhibitors
-
Pantoflickova D, Dorta G, Ravic M, Jornod P and Blum AL: Acid inhibition on the first day of dosing: comparison of four proton pump inhibitors. Aliment Pharmacol Ther 17: 1507-1514, 2003.
-
(2003)
Aliment Pharmacol Ther
, vol.17
, pp. 1507-1514
-
-
Pantoflickova, D.1
Dorta, G.2
Ravic, M.3
Jornod, P.4
Blum, A.L.5
-
7
-
-
0030930189
-
Sites of reaction of the gastric H, K-ATPase with extracytoplasmic thiol reagents
-
Besancon M, Simon A, Sachs G and Shin JM: Sites of reaction of the gastric H, K-ATPase with extracytoplasmic thiol reagents. J Biol Chem 272: 22438-22 4 4 6, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 22438-22446
-
-
Besancon, M.1
Simon, A.2
Sachs, G.3
Shin, J.M.4
-
8
-
-
0032883946
-
Causes and consequences of acidic pH in tumors: A magnetic resonance study
-
Stubbs M, McSheehy PM and Griffiths JR: Causes and consequences of acidic pH in tumors: a magnetic resonance study. Adv Enzyme Regul 39: 13-30, 1999.
-
(1999)
Adv Enzyme Regul
, vol.39
, pp. 13-30
-
-
Stubbs, M.1
McSheehy, P.M.2
Griffiths, J.R.3
-
9
-
-
0027966042
-
Metabolic consequences of a reversed pH gradient in rat tumors
-
Stubbs M, Rodrigues L, Howe FA, et al: Metabolic consequences of a reversed pH gradient in rat tumors. Cancer Res 54: 4011-4016, 1994.
-
(1994)
Cancer Res
, vol.54
, pp. 4011-4016
-
-
Stubbs, M.1
Rodrigues, L.2
Howe, F.A.3
-
10
-
-
0028920328
-
Substrate balances across colonic carcinomas in humans
-
Holm E, Hagmüller E, Staedt U, et al: Substrate balances across colonic carcinomas in humans. Cancer Res 55: 1373-1378, 1995.
-
(1995)
Cancer Res
, vol.55
, pp. 1373-1378
-
-
Holm, E.1
Hagmüller, E.2
Staedt, U.3
-
11
-
-
0024408986
-
Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
-
Vaupel P, Kallinowski F and Okunieff P: Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 49: 6449-6465, 1989.
-
(1989)
Cancer Res
, vol.49
, pp. 6449-6465
-
-
Vaupel, P.1
Kallinowski, F.2
Okunieff, P.3
-
12
-
-
0024379967
-
Acid pH in tumors and its potential for therapeutic exploitation
-
Tannock IF and Rotin D: Acid pH in tumors and its potential for therapeutic exploitation. Cancer Res 49: 4373-4384, 1989.
-
(1989)
Cancer Res
, vol.49
, pp. 4373-4384
-
-
Tannock, I.F.1
Rotin, D.2
-
13
-
-
0030614893
-
Interstitial pH and pO2gradients in solid tumors in vivo: High-resolution measurements reveal a lack of correlation
-
Helmlinger G, Yuan F, Dellian M and Jain RK: Interstitial pH and pO2gradients in solid tumors in vivo: high-resolution measurements reveal a lack of correlation. Nat Med 3: 177-182, 1997.
-
(1997)
Nat Med
, vol.3
, pp. 177-182
-
-
Helmlinger, G.1
Yuan, F.2
Dellian, M.3
Jain, R.K.4
-
14
-
-
11144226693
-
Selective induction of apoptosis with proton pump inhibitor in gastric cancer cells
-
Yeo M, Kim DK, Kim YB, et al: Selective induction of apoptosis with proton pump inhibitor in gastric cancer cells. Clin Cancer Res 10: 8687-8696, 2004.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 8687-8696
-
-
Yeo, M.1
Kim, D.K.2
Kim, Y.B.3
-
15
-
-
0028041009
-
Establishment and characterization of a SV40 transformed human fetal gastric epithelial cell line-GES-1
-
(In Chinese)
-
Ke Y, Ning T and Wang B: Establishment and characterization of a SV40 transformed human fetal gastric epithelial cell line-GES-1. Zhonghua Zhong Liu Za Zhi 16: 7-10, 1994 (In Chinese).
-
(1994)
Zhonghua Zhong Liu Za Zhi
, vol.16
, pp. 7-10
-
-
Ke, Y.1
Ning, T.2
Wang, B.3
-
17
-
-
70450284314
-
V-ATPase inhibitors and implication in cancer treatment
-
Pérez-Sayáns M, Somoza-Martín JM, Barros-Ang ueir a F, Rey JM and García-García A: V-ATPase inhibitors and implication in cancer treatment. Cancer Treat Rev 35: 707-713, 2009.
-
(2009)
Cancer Treat Rev
, vol.35
, pp. 707-713
-
-
Pérez-Sayáns, M.1
Somoza-Martín, J.M.2
Barros-Angueira, F.3
Rey, J.M.4
García-García, A.5
-
19
-
-
33847377377
-
Tumor acidity, chemoresistance and proton pump inhibitors
-
De Milito A and Fais S: Tumor acidity, chemoresistance and proton pump inhibitors. Future Oncol 1: 779-786, 2005.
-
(2005)
Future Oncol
, vol.1
, pp. 779-786
-
-
De Milito, A.1
Fais, S.2
-
21
-
-
36349001899
-
Targeting vacuolar H+-ATPases as a new strategy against cancer
-
Fais S, De Milito A, You H and Qin W: Targeting vacuolar H+-ATPases as a new strategy against cancer. Cancer Res 67: 10627-10 63 0, 2007.
-
(2007)
Cancer Res
, vol.67
, pp. 10627-10630
-
-
Fais, S.1
De Milito, A.2
You, H.3
Qin, W.4
-
22
-
-
2642674446
-
Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates
-
Kromer W, Krüger U, Huber R, Hartmann M and Steinijans VW: Differences in pH-dependent activation rates of substituted benzimidazoles and biological in vitro correlates. Pharmacology 56: 57-70, 1998.
-
(1998)
Pharmacology
, vol.56
, pp. 57-70
-
-
Kromer, W.1
Krüger, U.2
Huber, R.3
Hartmann, M.4
Steinijans, V.W.5
-
23
-
-
57849134122
-
Relative potency of proton-pump inhibitors-comparison of effects on intragastric pH
-
Kirchheiner J, Glatt S, Fuhr U, et al: Relative potency of proton-pump inhibitors-comparison of effects on intragastric pH. Eur J Clin Pharmacol 65: 19-31, 2009.
-
(2009)
Eur J Clin Pharmacol
, vol.65
, pp. 19-31
-
-
Kirchheiner, J.1
Glatt, S.2
Fuhr, U.3
-
24
-
-
84865708138
-
Rabeprazole for the treatment of acid-related disorders
-
Marelli S and Pace F: Rabeprazole for the treatment of acid-related disorders. Expert Rev Gastroenterol Hepatol 6: 423-435, 2012.
-
(2012)
Expert Rev Gastroenterol Hepatol
, vol.6
, pp. 423-435
-
-
Marelli, S.1
Pace, F.2
-
25
-
-
84857749232
-
A rationale for the use of proton pump inhibitors as antineoplastic agents
-
De Milito A, Marino ML and Fais S: A rationale for the use of proton pump inhibitors as antineoplastic agents. Curr Pharm Des 18: 1395-1406, 2012.
-
(2012)
Curr Pharm Des
, vol.18
, pp. 1395-1406
-
-
De Milito, A.1
Marino, M.L.2
Fais, S.3
-
26
-
-
0036481562
-
The vacuolar (H+)-ATPases-nature's most versatile proton pumps
-
Nishi T and Forgac M: The vacuolar (H+)-ATPases-nature's most versatile proton pumps. Nat Rev Mol Cell Biol 3: 94-103, 2002.
-
(2002)
Nat Rev Mol Cell Biol
, vol.3
, pp. 94-103
-
-
Nishi, T.1
Forgac, M.2
-
27
-
-
62149142874
-
V-ATPase functions in normal and disease processes
-
Hinton A, Bond S and Forgac M: V-ATPase functions in normal and disease processes. Pflugers Arch 457: 589-598, 2009.
-
(2009)
Pflugers Arch
, vol.457
, pp. 589-598
-
-
Hinton, A.1
Bond, S.2
Forgac, M.3
-
29
-
-
76749088358
-
Pathological roles of MAPK signaling pathways in human diseases
-
Kim EK and Choi EJ: Pathological roles of MAPK signaling pathways in human diseases. Biochim Biophys Acta 1802: 396-405, 2010.
-
(2010)
Biochim Biophys Acta
, vol.1802
, pp. 396-405
-
-
Kim, E.K.1
Choi, E.J.2
-
30
-
-
0034881019
-
Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals
-
Ballif BA and Blenis J: Molecular mechanisms mediating mammalian mitogen-activated protein kinase (MAPK) kinase (MEK)-MAPK cell survival signals. Cell Growth Differ 12: 397-408, 2001.
-
(2001)
Cell Growth Differ
, vol.12
, pp. 397-408
-
-
Ballif, B.A.1
Blenis, J.2
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