Shp2 signaling in POMC neurons is important for leptin’s actions on blood pressure, Energy balance, And glucose regulation

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 307, Issue 12, 2014, Pages R1438-R1447

  Do Carmo, Jussara M ^a   Da Silva, Alexandre A ^a   Ebaady, Sabira E ^a   Sessums, Price O ^a   Abraham, Ralph S ^a   Elmquist, Joel K ^b   Lowell, Bradford B ^c   Hall, John E ^a  

^a UNIVERSITY OF MISSISSIPPI SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c HARVARD MEDICAL SCHOOL   (United States)

Author keywords

Acute stress; Blood pressure; Energy balance; Glucose regulation; Heart rate

Indexed keywords

GLUCOSE; INSULIN; LEPTIN; PROOPIOMELANOCORTIN; PROTEIN TYROSINE PHOSPHATASE SHP 2; GLUCOSE BLOOD LEVEL; PTPN11 PROTEIN, MOUSE;

ACUTE DRUG ADMINISTRATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIDIABETIC ACTIVITY; ARTICLE; BLOOD PRESSURE; BRAIN NERVE CELL; CARDIOVASCULAR FUNCTION; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DOSE RESPONSE; DRUG INFUSION; ENERGY BALANCE; FOOD INTAKE; GENE DELETION; GLUCOSE BLOOD LEVEL; GLUCOSE HOMEOSTASIS; INSULIN BLOOD LEVEL; INTRACELLULAR SIGNALING; INTRAVENOUS CATHETER; MALE; MEAN ARTERIAL PRESSURE; METABOLIC REGULATION; MOLECULAR PROBE; MOUSE; NONHUMAN; PROTEIN FUNCTION; TEST MEAL; WEIGHT CONTROL; 129 MOUSE; ANIMAL; ARTERIAL PRESSURE; BLOOD; BODY WEIGHT; BRAIN; C57BL MOUSE; DEFICIENCY; DRUG EFFECTS; EATING; ENERGY METABOLISM; ENZYMOLOGY; GENETICS; HOMEOSTASIS; INTRAVENOUS DRUG ADMINISTRATION; KNOCKOUT MOUSE; METABOLISM; MOTOR ACTIVITY; NERVE CELL; OXYGEN CONSUMPTION; SIGNAL TRANSDUCTION; TIME FACTOR;

ANIMALS; ARTERIAL PRESSURE; BLOOD GLUCOSE; BODY WEIGHT; BRAIN; EATING; ENERGY METABOLISM; HOMEOSTASIS; INFUSIONS, INTRAVENOUS; INSULIN; LEPTIN; MALE; MICE, 129 STRAIN; MICE, INBRED C57BL; MICE, KNOCKOUT; MOTOR ACTIVITY; NEURONS; OXYGEN CONSUMPTION; PRO-OPIOMELANOCORTIN; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 11; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 84919432688     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00131.2014     Document Type: Article

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