메뉴 건너뛰기




Volumn 38, Issue 6, 2014, Pages 775-783

Role of Shp2 in forebrain neurons in regulating metabolic and cardiovascular functions and responses to leptin

Author keywords

acute stress; blood pressure; energy expenditure; food intake; heart rate; thermoneutrality

Indexed keywords

LEPTIN; PROTEIN SH2; LEPTIN RECEPTOR; PROTEIN TYROSINE PHOSPHATASE SHP 2; PTPN11 PROTEIN, MOUSE; SIGNAL PEPTIDE;

EID: 84902280984     PISSN: 03070565     EISSN: 14765497     Source Type: Journal    
DOI: 10.1038/ijo.2013.177     Document Type: Article
Times cited : (23)

References (20)
  • 1
    • 8644268830 scopus 로고    scopus 로고
    • Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism
    • Zhang EE, Chapeau E, Hagihara K, Feng GS. Neuronal Shp2 tyrosine phosphatase controls energy balance and metabolism. Proc Natl Acad Sci USA 2004; 101: 16064-16069.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 16064-16069
    • Zhang, E.E.1    Chapeau, E.2    Hagihara, K.3    Feng, G.S.4
  • 4
    • 33645883804 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by the brain-derived neurotrophic factor
    • East JB, Royer AR, Middlemas DS. The protein tyrosine phosphatase, Shp2, is required for the complete activation of the RAS/MAPK pathway by the brain-derived neurotrophic factor. J Neurochem 2006; 97: 834-845.
    • (2006) J Neurochem , vol.97 , pp. 834-845
    • East, J.B.1    Royer, A.R.2    Middlemas, D.S.3
  • 6
    • 77955458427 scopus 로고    scopus 로고
    • Reduced body weight and increased energy expenditure in transgenic mice over-expressing soluble leptin receptor
    • Lou PH, Yang G, Huang L, Cui Y, Pourbahrami T, Radda GK et al. Reduced body weight and increased energy expenditure in transgenic mice over-expressing soluble leptin receptor. PLoS One 2010; 20: e11669.
    • (2010) PLoS One , vol.20
    • Lou, P.H.1    Yang, G.2    Huang, L.3    Cui, Y.4    Pourbahrami, T.5    Radda, G.K.6
  • 7
    • 69149095206 scopus 로고    scopus 로고
    • Leptin-mediated changes in hepatic mitochondrial metabolism, structure and protein levels
    • Singh A, Wirtz M, Parker N, Hogan M, Strahler J, Michailidis G et al. Leptin-mediated changes in hepatic mitochondrial metabolism, structure and protein levels. Proc Natl Acad Sci USA 2009; 106: 13100-13105.
    • (2009) Proc Natl Acad Sci USA , vol.106 , pp. 13100-13105
    • Singh, A.1    Wirtz, M.2    Parker, N.3    Hogan, M.4    Strahler, J.5    Michailidis, G.6
  • 8
    • 0031606279 scopus 로고    scopus 로고
    • Chronic leptin infusion increases arterial pressure
    • Shek EW, Brands MW, Hall JE. Chronic leptin infusion increases arterial pressure. Hypertension 1998; 31: 409-414.
    • (1998) Hypertension , vol.31 , pp. 409-414
    • Shek, E.W.1    Brands, M.W.2    Hall, J.E.3
  • 9
    • 77952893301 scopus 로고    scopus 로고
    • Obesity-induced hypertension: Role of sympathetic nervous system, leptin and melanocortins
    • Hall JE, da Silva AA, do Carmo JM, Dubinion J, Hamza S, Munusamy S et al. Obesity-induced hypertension: role of sympathetic nervous system, leptin and melanocortins. J Biol Chem 2010; 285: 17271-17276.
    • (2010) J Biol Chem , vol.285 , pp. 17271-17276
    • Hall, J.E.1    Da Silva, A.A.2    Do Carmo, J.M.3    Dubinion, J.4    Hamza, S.5    Munusamy, S.6
  • 11
    • 79955471654 scopus 로고    scopus 로고
    • Control of blood pressure, appetite and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons
    • do Carmo JM, da Silva AA, Cai Z, Lin S, Dubinion JH, Hall JE. Control of blood pressure, appetite and glucose by leptin in mice lacking leptin receptors in proopiomelanocortin neurons. Hypertension 2011; 57: 918-926.
    • (2011) Hypertension , vol.57 , pp. 918-926
    • Do Carmo, J.M.1    Da Silva, A.A.2    Cai, Z.3    Lin, S.4    Dubinion, J.H.5    Hall, J.E.6
  • 12
    • 33745986945 scopus 로고    scopus 로고
    • Melanocortin-4 receptor mediates chronic cardiovascular and metabolic actions of leptin
    • Tallam LS, da Silva AA, Hall JE. Melanocortin-4 receptor mediates chronic cardiovascular and metabolic actions of leptin. Hypertension 2006; 48: 58-64.
    • (2006) Hypertension , vol.48 , pp. 58-64
    • Tallam, L.S.1    Da Silva, A.A.2    Hall, J.E.3
  • 13
    • 43449123047 scopus 로고    scopus 로고
    • Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase
    • Krajewska M, Banares S, Zhang EE, Huang X, Scadeng M, Jhala US et al. Development of diabesity in mice with neuronal deletion of Shp2 tyrosine phosphatase. Am J Pathol 2008; 172: 1312-1324.
    • (2008) Am J Pathol , vol.172 , pp. 1312-1324
    • Krajewska, M.1    Banares, S.2    Zhang, E.E.3    Huang, X.4    Scadeng, M.5    Jhala, U.S.6
  • 14
    • 0033512117 scopus 로고    scopus 로고
    • Contrasting blood pressure effects of obesity in leptin deficient ob/ob mice and agouti yellow obese mice
    • Mark AL, Shafer RA, Correia ML, Morgan DA, Sigmund CD, Haynes WG. Contrasting blood pressure effects of obesity in leptin deficient ob/ob mice and agouti yellow obese mice. J Hypertens 1999; 17: 1949-1953.
    • (1999) J Hypertens , vol.17 , pp. 1949-1953
    • Mark, A.L.1    Shafer, R.A.2    Correia, M.L.3    Morgan, D.A.4    Sigmund, C.D.5    Haynes, W.G.6
  • 15
    • 84890776517 scopus 로고    scopus 로고
    • Control of cardiovascular, metabolic and respiratory functions during prolonged obesity in leptin-deficient and diet-induced obese mice
    • 2008
    • do Carmo JM, Bassi M, da Silva AA, Hall JE. Control of cardiovascular, metabolic and respiratory functions during prolonged obesity in leptin-deficient and diet-induced obese mice. Hypertension 2008; 15: 109 2008.
    • (2008) Hypertension , vol.15 , pp. 109
    • Do Carmo, J.M.1    Bassi, M.2    Da Silva, A.A.3    Hall, J.E.4
  • 16
    • 0033304576 scopus 로고    scopus 로고
    • Human leptin deficiency caused by a missense mutation: Multiple endocrine defects, decreased sympathetic tone and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin and spontaneous correction of leptin-mediated defects
    • Ozata M, Ozdemir IC, Licinio J. Human leptin deficiency caused by a missense mutation: multiple endocrine defects, decreased sympathetic tone and immune system dysfunction indicate new targets for leptin action, greater central than peripheral resistance to the effects of leptin and spontaneous correction of leptin-mediated defects. J Clin Endocrinol Metab 1999; 10: 3686-3695.
    • (1999) J Clin Endocrinol Metab , vol.10 , pp. 3686-3695
    • Ozata, M.1    Ozdemir, I.C.2    Licinio, J.3
  • 17
    • 33845567553 scopus 로고    scopus 로고
    • Genetics of obesity in humans
    • Farooqi S, O'Rahilly S. Genetics of obesity in humans. Endocr Rev 2006; 27: 710-718.
    • (2006) Endocr Rev , vol.27 , pp. 710-718
    • Farooqi, S.1    O'Rahilly, S.2
  • 19
    • 0023373752 scopus 로고
    • Cold-induced thermogenesis in rats nutritionally deprived early in life
    • Muralidhara DV, Shetty PS. Cold-induced thermogenesis in rats nutritionally deprived early in life. Indian J Physiol Pharmacol 1987; 31: 149-158.
    • (1987) Indian J Physiol Pharmacol , vol.31 , pp. 149-158
    • Muralidhara, D.V.1    Shetty, P.S.2
  • 20
    • 0035096828 scopus 로고    scopus 로고
    • Central leptin attenuates the cardiovascular and metabolic effects of fasting in rats
    • Overton JM, Williams TD, Chambers JB, Rashotte ME. Central leptin attenuates the cardiovascular and metabolic effects of fasting in rats. Hypertension 2001; 37: 663-669.
    • (2001) Hypertension , vol.37 , pp. 663-669
    • Overton, J.M.1    Williams, T.D.2    Chambers, J.B.3    Rashotte, M.E.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.