The habenulo-raphe serotonergic circuit encodes an aversive expectation value essential for adaptive active avoidance of danger

Neuron

Volumn 84, Issue 5, 2014, Pages 1034-1048

  Amo, Ryunosuke ^a,b   Fredes, Felipe ^a   Kinoshita, Masae ^a   Aoki, Ryo ^a,c   Aizawa, Hidenori ^a   Agetsuma, Masakazu ^a   Aoki, Tazu ^a   Shiraki, Toshiyuki ^a   Kakinuma, Hisaya ^a   Matsuda, Masaru ^d   Yamazaki, Masako ^a   Takahoko, Mikako ^a   Tsuboi, Takashi ^c   Higashijima, Shin ichi ^e   Miyasaka, Nobuhiko ^a   Koide, Tetsuya ^a   Yabuki, Yoichi ^a   Yoshihara, Yoshihiro ^a   Fukai, Tomoki ^a   Okamoto, Hitoshi ^a,b,c  

^a RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^b WASEDA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO   (Japan)

^d UTSUNOMIYA UNIVERSITY   (Japan)

^e OKAZAKI INSTITUTE FOR INTEGRATIVE BIOSCIENCE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ADAPTIVE ACTIVE AVOIDANCE; ADULT; ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AVERSIVE BEHAVIOR; AVOIDANCE BEHAVIOR; CELL ACTIVATION; CELL STIMULATION; CLASSICAL FEAR CONDITIONING; CONDITIONING; CONTROLLED STUDY; ENTOPEDUNCULAR NUCLEUS; ESCAPE BEHAVIOR; GLUTAMATERGIC NERVE CELL; GLUTAMATERGIC TRANSMISSION; HABENULA; HABENULO RAPHE SEROTONERGIC CIRCUIT; HAZARD; LATERAL HABENULA; MEDIAN RAPHE NUCLEUS; MOLECULAR DYNAMICS; NERVE CELL; NERVE PROJECTION; NERVOUS SYSTEM FUNCTION; NONHUMAN; OPTOGENETICS; PAVLOVIAN CONDITIONING; PREDICTIVE VALUE; REINFORCEMENT; SEROTONERGIC TRANSMISSION; SEROTONINERGIC NERVE CELL; SYNAPTIC TRANSMISSION; VENTRAL HABENULA; ZEBRA FISH; ACTION POTENTIAL; ADAPTIVE BEHAVIOR; ANIMAL; ASSOCIATION; CONDITIONED REFLEX; CYTOLOGY; FEAR; GENETICS; MALE; METABOLISM; NERVE TRACT; PHYSIOLOGY; RAPHE NUCLEUS; TRANSGENIC ANIMAL;

5,7 DIHYDROXYTRYPTAMINE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; PET1 PROTEIN, ZEBRAFISH; PHOTOPROTEIN; SEROTONIN; TRANSCRIPTION FACTOR; VESICULAR GLUTAMATE TRANSPORTER 2; ZEBRAFISH PROTEIN;

5,7-DIHYDROXYTRYPTAMINE; ACTION POTENTIALS; ADAPTATION, PSYCHOLOGICAL; ANIMALS; ANIMALS, GENETICALLY MODIFIED; AVOIDANCE LEARNING; CONDITIONING, CLASSICAL; CUES; FEAR; HABENULA; LUMINESCENT PROTEINS; MALE; NEURAL PATHWAYS; NEUROTRANSMITTER AGENTS; RAPHE NUCLEI; SEROTONERGIC NEURONS; SEROTONIN; TRANSCRIPTION FACTORS; VESICULAR GLUTAMATE TRANSPORT PROTEIN 2; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84919424931     PISSN: 08966273     EISSN: 10974199     Source Type: Journal    
DOI: 10.1016/j.neuron.2014.10.035     Document Type: Article

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