Unusually Broad Substrate Profile of Self-Sufficient Cytochrome P450 Monooxygenase CYP116B4 from Labrenzia aggregata

ChemBioChem

Volumn 15, Issue 16, 2014, Pages 2443-2449

  Yin, Yue Cai ^a   Yu, Hui Lei ^a,b   Luan, Zheng Jiao ^a   Li, Ren Jie ^a   Ouyang, Peng Fei ^a   Liu, Jing ^a   Xu, Jian He ^a,b  

^a EAST CHINA UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

^b SHANGHAI COLLABORATIVE INNOVATION CENTER FOR BIOMANUFACTURING TECHNOLOGY   (China)

Author keywords

Cytochromes; Data mining; Hydroxylation; Oxidoreductases; Protein engineering; Substrate promiscuity

Indexed keywords

ALKYLBENZENE; AROMATIC COMPOUND; BACTERIAL ENZYME; CYTOCHROME P450; CYTOCHROME P450 116B4; TERPENOID; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; RECOMBINANT PROTEIN;

ARTICLE; CATALYST; CHEMICAL BOND; DATA MINING; DEALKYLATION; ENZYME PURIFICATION; ENZYME SUBSTRATE; EPOXIDATION; ESCHERICHIA COLI; HYDROXYLATION; LABRENZIA AGGREGATA; NONHUMAN; PROTEIN EXPRESSION; RHODOCOCCUS; STEREOCHEMISTRY; SULFOXIDATION; AMINO ACID SEQUENCE; BIOCATALYSIS; BIOSYNTHESIS; ENZYME SPECIFICITY; ENZYMOLOGY; GENETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN ENGINEERING; RHODOBACTERACEAE; SEQUENCE ALIGNMENT;

AGGREGATA; BACTERIA (MICROORGANISMS); ESCHERICHIA COLI;

AMINO ACID SEQUENCE; BIOCATALYSIS; CYTOCHROME P-450 ENZYME SYSTEM; ESCHERICHIA COLI; HYDROXYLATION; MOLECULAR SEQUENCE DATA; PROTEIN ENGINEERING; RECOMBINANT PROTEINS; RHODOBACTERACEAE; SEQUENCE ALIGNMENT; SUBSTRATE SPECIFICITY;

EID: 84919386791     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201402309     Document Type: Article

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