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Atack JR, Wafford KA, Tye SJ, Cook SM, Sohal B, Pike A, Sur C, Melillo D, Bristow L, Bromidge F, Ragan I, Kerby J, Street L, Carling R, Castro JL, Whiting P, Dawson GR, McKernan RM. TPA023 [7-(1,1-Dimethylethyl)-6-(2-ethyl-2H-1,2,4-triazol-3-ylmethoxy)-3-(2-fluorophenyl)-1,2,4-triazolo[4,3-b] pyridazine], a receptor modulator selective for 2-and 3-containing GABAA receptors, is a nonsedating anxiolytic in rodents and primates. J Pharmacol Exp Ther 2006; 316: 410-22.
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Wafford, K.A.2
Tye, S.J.3
Cook, S.M.4
Sohal, B.5
Pike, A.6
Sur, C.7
Melillo, D.8
Bristow, L.9
Bromidge, F.10
Ragan, I.11
Kerby, J.12
Street, L.13
Carling, R.14
Castro, J.L.15
Whiting, P.16
Dawson, G.R.17
McKernan, R.M.18
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