Expression of human complement factor h prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged cfh knockout mice

American Journal of Pathology

Volumn 185, Issue 1, 2015, Pages 29-42

  Ding, Jin Dong ^a   Kelly, Una ^a   Landowski, Michael ^a   Toomey, Christopher B ^a   Groelle, Marybeth ^a   Miller, Chelsey ^a   Smith, Stephanie G ^a   Klingeborn, Mikael ^a   Singhapricha, Terry ^a   Jiang, Haixiang ^a   Frank, Michael M ^a   Bowes Rickman, Catherine ^a  

^a DUKE UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALTERNATIVE COMPLEMENT PATHWAY C3 C5 CONVERTASE; COMPLEMENT COMPONENT C3; COMPLEMENT FACTOR H; COMPLEMENT FACTOR H, HUMAN;

AGE RELATED MACULAR DEGENERATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL ARTIFICIAL CHROMOSOME; CHOROID; COMPLEMENT SYSTEM; CONTROLLED STUDY; DARK ADAPTATION; ELECTRORETINOGRAPHY; GENOTYPE; HUMAN; KIDNEY MALFORMATION; MOUSE; NONHUMAN; PATHOGENESIS; PIGMENT EPITHELIUM; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; RETINA INJURY; SCLERA; VISION; ANIMAL; C57BL MOUSE; CROSS BREEDING; GENETICS; KIDNEY DISEASE; KNOCKOUT MOUSE; MACULAR DEGENERATION; METABOLISM; PATHOLOGY; PHENOTYPE; RETINA; RETINA DISEASE; RETINAL PIGMENT EPITHELIUM; SHEEP;

ANIMALS; CHOROID; COMPLEMENT C3; COMPLEMENT FACTOR H; CROSSES, GENETIC; ELECTRORETINOGRAPHY; HUMANS; KIDNEY DISEASES; MACULAR DEGENERATION; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PHENOTYPE; RETINA; RETINAL DISEASES; RETINAL PIGMENT EPITHELIUM; SCLERA; SHEEP;

EID: 84918826384     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2014.08.026     Document Type: Article

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