Association of microRNA-146a and its target gene IRAK1 polymorphism with enthesitis related arthritis category of juvenile idiopathic arthritis

Rheumatology International

Volumn 34, Issue 10, 2014, Pages 1395-1400

  Singh, Sushma ^a   Rai, Geeta ^b   Aggarwal, Amita ^a  

^a SANJAY GANDHI POSTGRADUATE INSTITUTE OF MEDICAL SCIENCES   (India)

^b BANARAS HINDU UNIVERSITY   (India)

Author keywords

JIA ERA; MicroRNAs; miR 146a; Polymorphisms; rs2910164

Indexed keywords

INTERLEUKIN 1 RECEPTOR ASSOCIATED KINASE; IRAK1 PROTEIN, HUMAN; MICRORNA; MIRN146 MICRORNA, HUMAN;

ADOLESCENT; ADULT; ALLELE; CHILD; FEMALE; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC PREDISPOSITION; GENETICS; GENOTYPE; HUMAN; JUVENILE RHEUMATOID ARTHRITIS; MALE; MIDDLE AGED; PRESCHOOL CHILD; SINGLE NUCLEOTIDE POLYMORPHISM; UVEITIS; YOUNG ADULT;

ADOLESCENT; ADULT; ALLELES; ARTHRITIS, JUVENILE; CHILD; CHILD, PRESCHOOL; FEMALE; GENE FREQUENCY; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASES; LINKAGE DISEQUILIBRIUM; MALE; MICRORNAS; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; UVEITIS; YOUNG ADULT;

EID: 84918826363     PISSN: 01728172     EISSN: 1437160X     Source Type: Journal    
DOI: 10.1007/s00296-014-3001-7     Document Type: Article

References (30)

1. Petty RE, Southwood TR, Manners P, Baum J, Glass DN, Goldenberg J et al (2004) International League of Associations for rheumatology classification of juvenile idiopathic arthritis: 2nd revision, Edmonton, 2001. J Rheumatol 31:390–392
2. Aggarwal A, Agarwal V, Danda D, Misra R (2004) Outcome in juvenile rheumatoid arthritis in India. Indian Pediatr 41:180–184
3. Kunjir V, Venugopalan A, Chopra A (2010) Profile of Indian patients with juvenile onset chronic inflammatory joint disease using the ILAR classification criteria for JIA: a community-based cohort study. J Rheumatol 37:1756–1762
4. Ellis JA, Munro JE, Ponsonby AE (2010) Possible environmental determinants of juvenile idiopathic arthritis. Rheumatology 49:411–425
5. Donn RP, Ollier WE (1996) Juvenile chronic arthritis—a time for change? Eur J Immunogenet 23:245
6. Anne H, Paul M, Edward F, Steve E, Jon P, Anne B et al (2011) Subtype specific genetic associations for juvenile idiopathic arthritis: ERAP 1 with the enthesitis related arthritis subtype and IL-23R with juvenile psoriatic arthritis. Arthritis Res Ther 13:R12
7. Myles A, Rahman MT, Aggarwal A (2012) Membrane bound toll like receptors are over expressed in peripheral blood and synovial fluid mononuclear cells of enthesitis related arthritis category of juvenile idiopathic arthritis (JIA–ERA) patients and lead to secretion of inflammatory mediators. J Clin Immunol 32:488–496
8. Taganov KD, Boldin MP, Chang KJ et al (2006) NF-kappaB-dependent induction of microRNA miR-146, an inhibitor targeted to signalling proteins of innate immune responses. Proc Natl Acad Sci USA 103:12481–12486
9. Zamore PD, Haley B (2005) Ribo-genome: the big world of small RNAs. Science 309:1519–1524
10. Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE (2008) Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis. Arthritis Rheum 58:1001–1009
11. Pauley KM, Satoh M, Chan AL, Bubb MR, Reeves WH, Chan EKL (2008) Upregulated MIR146A expression in peripheral blood mononuclear cells from rheumatoid arthritis patients. Arthritis Res Ther 10:101
12. Hu Z, Chen J, Tian T, Zhou X, Gu H, Xu L et al (2008) Genetic variants of miRNA sequences and non-small cell lung cancer survival. J Clin Invest 118:2600–2608
13. Iwai N, Naraba H (2005) Polymorphisms in human pre miRNAs. Biochem Biophys Res Commun 331:1439–1444
14. Filipowicz W, Bhattacharyya SN, Sonenberg N (2008) Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight? Nat Rev Genet 9:102–114
15. Jacob CO, Lee SK, Strassmann G (1996) Mutational analysis of TNF-alpha gene reveals a regulatory role for the 3’-untranslated region in the genetic predisposition to lupus-like autoimmune disease. J Immunol 156:3043–3050
16. Hashemi M, Eskandari-Nasab E, Zakeri Z, Atabaki M, Bahari G, Jahantigh M et al (2013) Association of pre-miRNA-146a rs2910164 and pre-miRNA-499 rs3746444 polymorphisms and susceptibility to rheumatoid arthritis. Mol Med Rep 7:287–291
17. Jiménez-Morales S, Gamboa-Becerra R, Baca V, Del Río-Navarro BE, López-Ley DY, Velázquez-Cruz R et al (2012) MIR146A polymorphism is associated with asthma but not with systemic lupus erythematosus and juvenile rheumatoid arthritis in Mexican patients. Tissue Antigens 80:317–321
18. Chatzikyriakidou A, Voulgari PV, Georgiou I, Drosos AA (2010) The role of microRNA-146a (MIR146A) and its target IL-1R-associated kinase (IRAK1) in psoriatic arthritis susceptibility. Scand J Immunol 71:382–385
19. Chatzikyriakidou A, Voulgari PV, Georgiou I, Drosos AA (2010) A polymorphism in the 3’-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of MIR146A, is associated with rheumatoid arthritis susceptibility. Joint Bone Spine 77:411–413
20. Zhang H, Pu J, Wang X, Shen L, Zhao G, Zhuang C et al (2013) IRAK1 rs3027898 C/A polymorphism is associated with risk of rheumatoid arthritis. Rheumatol Int 33:369–375
21. Umar M, Upadhyay R, Prakash G, Kumar S, Ghoshal UC, Mittal B (2012) Evaluation of common genetic variants in pre-microRNA in susceptibility and prognosis of esophageal cancer. Mol Carcinog 52:E10–E18
22. Löfgren Sara E, Frostegård Johan, Truedsson Lennart, Pons-Estel Bernardo A, D’Alfonso Sandra, Witte Torsten et al (2012) Genetic association of miRNA146a with systemic lupus erythematosus in Europeans through decreased expression of the gene. Genes Immun 13(3):268–274
23. Garcia AI, Cox DG, Barjhoux L, Verny-Pierre C, Barnes D et al (2011) The rs2910164:G.C SNP in the MIR146A gene is not associated with breast cancer risk in BRCA1 and BRCA2 mutation carriers. Hum Mutat 32(9):1004–1007
24. Catucci I, Yang R, Verderio P, Pizzamiglio S, Heesen L et al (2010) Evaluation of SNPs in miR-146a, miR196a2 and miR-499 as low-penetrance alleles in German and Italian familial breast cancer cases. Hum Mutat 31:E1052–E1057
25. Wei W-J, Wang Y-L, Li D-S, Wang Y, Wang X-F et al (2013) Association between the rs2910164 polymorphism in Pre-Mir-146a sequence and thyroid carcinogenesis. PLoS ONE 8(2):e56638
26. Song M-Y, Su H-J, Zhang L, Ma J-l, Li J-Y et al (2013) Genetic polymorphisms of miR-146a and miR-27a, H. pylori Infection, and risk of gastric lesions in a Chinese population. PLoS ONE 8(4):e61250
27. Ramkaran P, Khan S, Phulukdaree A, Moodley D, Chuturgoon AA (2014) miR-146a polymorphism influences levels of miR- 156a, IRAK-1, and TRAF-6 in young patients with coronary artery disease. Cell Biochem Biophys 68:259–266
28. Xiong XD, Cho M, Cai XP, Cheng J, Jing X, Cen JM, Liu X, Yang XL, Suh Y. (2014) A common variant in pre-miR-146 is associated with coronary artery disease risk and its mature miRNA expression. Mutat Res. Jan 19. pii: S0027-5107(14)00002-5
29. Jazdzewski K, Murray EL, Franssila K, Jarzab B, Schoenberg DR, de la Chapelle A (2008) Common SNP in pre-miR-146a decreases mature miR expression and predisposes to papillary thyroid carcinoma. Proc Natl Acad Sci USA 105:7269–7274
30. Xu T, Zhu Y, Wei QK, Yuan Y, Zhou F, Ge YY, Yang JR, Su H, Zhuang SM (2008) A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma. Carcinogenesis 29:2126–2131