메뉴 건너뛰기




Volumn 37, Issue 5, 2014, Pages 1355-1365

Oxidative Stress and Inflammation Are Differentially Affected by Atorvastatin, Pravastatin, Rosuvastatin, and Simvastatin on Lungs from Mice Exposed to Cigarette Smoke

Author keywords

cigarette smoke; inflammation; lung; mice; oxidative stress; statins

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; ATORVASTATIN; CATALASE; CIGARETTE SMOKE; GLUTATHIONE; GLUTATHIONE DISULFIDE; HYDROGEN PEROXIDE; KERATINOCYTE DERIVED CHEMOKINE; LIPID HYDROPEROXIDE; MONOCYTE CHEMOTACTIC PROTEIN 1; MYELOPEROXIDASE; NITRIC OXIDE; NITRITE; PRAVASTATIN; REACTIVE OXYGEN METABOLITE; ROSUVASTATIN; SIMVASTATIN; SUPEROXIDE DISMUTASE; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; AUTACOID; FLUOROBENZENE; HEPTANOIC ACID DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; PYRIMIDINE DERIVATIVE; PYRROLE DERIVATIVE; SULFONAMIDE;

EID: 84918793005     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9860-y     Document Type: Article
Times cited : (37)

References (80)
  • 1
    • 33747838497 scopus 로고    scopus 로고
    • State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer
    • PID: 16921139, COI: 1:CAS:528:DC%2BD28XpsVerurc%3D
    • Brody, J.S., and A. Spira. 2006. State of the art. Chronic obstructive pulmonary disease, inflammation, and lung cancer. Proceedings of the American Thoracic Society 3: 535–7.
    • (2006) Proceedings of the American Thoracic Society , vol.3 , pp. 535-537
    • Brody, J.S.1    Spira, A.2
  • 2
    • 33645053487 scopus 로고    scopus 로고
    • COPD exacerbations. 2: aetiology
    • PID: 16517585, COI: 1:STN:280:DC%2BD287jtFWnuw%3D%3D
    • Sapey, E., and R.A. Stockley. 2006. COPD exacerbations. 2: aetiology. Thorax 61: 250–8.
    • (2006) Thorax , vol.61 , pp. 250-258
    • Sapey, E.1    Stockley, R.A.2
  • 3
    • 0141625114 scopus 로고    scopus 로고
    • History of tobacco and health
    • PID: 14528877
    • Musk, A.W., and N.H. de Klerk. 2003. History of tobacco and health. Respirology 8: 286–90.
    • (2003) Respirology , vol.8 , pp. 286-290
    • Musk, A.W.1    de Klerk, N.H.2
  • 5
    • 14944383817 scopus 로고    scopus 로고
    • Models of chronic obstructive pulmonary disease
    • PID: 15522115
    • Groneberg, D.A., and K.F. Chung. 2004. Models of chronic obstructive pulmonary disease. Respiratory Research 5: 18.
    • (2004) Respiratory Research , vol.5 , pp. 18
    • Groneberg, D.A.1    Chung, K.F.2
  • 7
    • 0027247805 scopus 로고
    • Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite
    • PID: 8512242, COI: 1:CAS:528:DyaK3sXkvVygur0%3D, discussion 27-8
    • Pryor, W.A., and K. Stone. 1993. Oxidants in cigarette smoke. Radicals, hydrogen peroxide, peroxynitrate, and peroxynitrite. Annals of the New York Academy of Sciences 686: 12–27. discussion 27-8.
    • (1993) Annals of the New York Academy of Sciences , vol.686 , pp. 12-27
    • Pryor, W.A.1    Stone, K.2
  • 9
    • 39949083739 scopus 로고    scopus 로고
    • Mate tea reduced acute lung inflammation in mice exposed to cigarette smoke
    • PID: 18281194, COI: 1:CAS:528:DC%2BD1cXjtVSqu7w%3D
    • Lanzetti, M., F.S. Bezerra, B. Romana-Souza, A.C. Brando-Lima, V.L. Koatz, L.C. Porto, et al. 2008. Mate tea reduced acute lung inflammation in mice exposed to cigarette smoke. Nutrition 24: 375–81.
    • (2008) Nutrition , vol.24 , pp. 375-381
    • Lanzetti, M.1    Bezerra, F.S.2    Romana-Souza, B.3    Brando-Lima, A.C.4    Koatz, V.L.5    Porto, L.C.6
  • 10
    • 33750620057 scopus 로고    scopus 로고
    • Oxidative stress and redox regulation of lung inflammation in COPD
    • PID: 16816350, COI: 1:CAS:528:DC%2BD28XnslGqtrk%3D
    • Rahman, I., and I.M. Adcock. 2006. Oxidative stress and redox regulation of lung inflammation in COPD. European Respiratory Journal 28: 219–42.
    • (2006) European Respiratory Journal , vol.28 , pp. 219-242
    • Rahman, I.1    Adcock, I.M.2
  • 11
    • 61849159861 scopus 로고    scopus 로고
    • Involvement of nitric oxide in acute lung inflammation induced by cigarette smoke in the mouse
    • PID: 19070674, COI: 1:CAS:528:DC%2BD1MXjt1ahsbg%3D
    • Valenca, S.S., W.A. Pimenta, C.R. Rueff-Barroso, T.S. Ferreira, A.C. Resende, R.S. Moura, et al. 2009. Involvement of nitric oxide in acute lung inflammation induced by cigarette smoke in the mouse. Nitric Oxide 20: 175–81.
    • (2009) Nitric Oxide , vol.20 , pp. 175-181
    • Valenca, S.S.1    Pimenta, W.A.2    Rueff-Barroso, C.R.3    Ferreira, T.S.4    Resende, A.C.5    Moura, R.S.6
  • 12
    • 0031013116 scopus 로고    scopus 로고
    • Effect of vitamin A supplementation on cigarette smoke-induced lipid peroxidation
    • PID: 9004461, COI: 1:CAS:528:DyaK2sXpt1ejtQ%3D%3D
    • Helen, A., and P.L. Vijayammal. 1997. Effect of vitamin A supplementation on cigarette smoke-induced lipid peroxidation. Veterinary and Human Toxicology 39: 18–21.
    • (1997) Veterinary and Human Toxicology , vol.39 , pp. 18-21
    • Helen, A.1    Vijayammal, P.L.2
  • 13
    • 33750419261 scopus 로고    scopus 로고
    • The role of reactive nitrogen species and cigarette smoke in activation of transcription factor NF-kappaB and implication to inflammatory processes
    • PID: 17072028
    • Bar-Shai, M., E. Hasnis, Z. Wiener-Megnazi, and A.Z. Reznick. 2006. The role of reactive nitrogen species and cigarette smoke in activation of transcription factor NF-kappaB and implication to inflammatory processes. Journal of Physiology and Pharmacology 57(Suppl 4): 39–44.
    • (2006) Journal of Physiology and Pharmacology , vol.57 , pp. 39-44
    • Bar-Shai, M.1    Hasnis, E.2    Wiener-Megnazi, Z.3    Reznick, A.Z.4
  • 14
    • 0033984436 scopus 로고    scopus 로고
    • Current perspectives on statins
    • PID: 10637210, COI: 1:CAS:528:DC%2BD3cXptFKlug%3D%3D
    • Maron, D.J., S. Fazio, and M.F. Linton. 2000. Current perspectives on statins. Circulation 101: 207–13.
    • (2000) Circulation , vol.101 , pp. 207-213
    • Maron, D.J.1    Fazio, S.2    Linton, M.F.3
  • 16
    • 17344385356 scopus 로고    scopus 로고
    • The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells
    • PID: 12226549, COI: 1:CAS:528:DC%2BD38XnsVCkur0%3D
    • Morikawa, S., W. Takabe, C. Mataki, T. Kanke, T. Itoh, Y. Wada, et al. 2002. The effect of statins on mRNA levels of genes related to inflammation, coagulation, and vascular constriction in HUVEC. Human umbilical vein endothelial cells. Journal of Atherosclerosis and Thrombosis 9: 178–83.
    • (2002) Journal of Atherosclerosis and Thrombosis , vol.9 , pp. 178-183
    • Morikawa, S.1    Takabe, W.2    Mataki, C.3    Kanke, T.4    Itoh, T.5    Wada, Y.6
  • 17
    • 80055069473 scopus 로고    scopus 로고
    • Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation
    • PID: 21731885, COI: 1:CAS:528:DC%2BC3MXns1yitrY%3D
    • Sezer, E.D., E.Y. Sozmen, D. Nart, and T. Onat. 2011. Effect of atorvastatin therapy on oxidant-antioxidant status and atherosclerotic plaque formation. Vascular Health and Risk Management 7: 333–43.
    • (2011) Vascular Health and Risk Management , vol.7 , pp. 333-343
    • Sezer, E.D.1    Sozmen, E.Y.2    Nart, D.3    Onat, T.4
  • 18
    • 68749092225 scopus 로고    scopus 로고
    • Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1
    • PID: 19226281, COI: 1:CAS:528:DC%2BD1MXlsVWmurw%3D
    • Heeba, G., M.E. Moselhy, M. Hassan, M. Khalifa, R. Gryglewski, and T. Malinski. 2009. Anti-atherogenic effect of statins: role of nitric oxide, peroxynitrite and haem oxygenase-1. British Journal of Pharmacology 156: 1256–66.
    • (2009) British Journal of Pharmacology , vol.156 , pp. 1256-1266
    • Heeba, G.1    Moselhy, M.E.2    Hassan, M.3    Khalifa, M.4    Gryglewski, R.5    Malinski, T.6
  • 19
    • 84857062268 scopus 로고    scopus 로고
    • Effects of Euterpe oleracea Mart. (ACAI) extract in acute lung inflammation induced by cigarette smoke in the mouse
    • PID: 22138278
    • Moura, R.S., T.S. Ferreira, A.A. Lopes, K.M. Pires, R.T. Nesi, A.C. Resende, et al. 2012. Effects of Euterpe oleracea Mart. (ACAI) extract in acute lung inflammation induced by cigarette smoke in the mouse. Phytomedicine 19: 262–9.
    • (2012) Phytomedicine , vol.19 , pp. 262-269
    • Moura, R.S.1    Ferreira, T.S.2    Lopes, A.A.3    Pires, K.M.4    Nesi, R.T.5    Resende, A.C.6
  • 20
    • 80051495838 scopus 로고    scopus 로고
    • Grape skin extract reduced pulmonary oxidative response in mice exposed to cigarette smoke
    • PID: 21804454, COI: 1:CAS:528:DC%2BC3MXhsVelurfI
    • Pires, K.M., S.S. Valenca, A.C. Resende, L.C. Porto, E.F. Queiroz, D.D. Moreira, et al. 2011. Grape skin extract reduced pulmonary oxidative response in mice exposed to cigarette smoke. Medical Science Monitor 17: BR187–195.
    • (2011) Medical Science Monitor , vol.17 , pp. BR187-BR195
    • Pires, K.M.1    Valenca, S.S.2    Resende, A.C.3    Porto, L.C.4    Queiroz, E.F.5    Moreira, D.D.6
  • 21
    • 33750620129 scopus 로고    scopus 로고
    • Alpha-tocopherol and ascorbic acid supplementation reduced acute lung inflammatory response by cigarette smoke in mouse
    • PID: 17095405, COI: 1:CAS:528:DC%2BD28Xht1SjsrnJ
    • Silva Bezerra, F., S.S. Valenca, M. Lanzetti, W.A. Pimenta, P. Castro, V.L. Goncalves Koatz, et al. 2006. Alpha-tocopherol and ascorbic acid supplementation reduced acute lung inflammatory response by cigarette smoke in mouse. Nutrition 22: 1192–201.
    • (2006) Nutrition , vol.22 , pp. 1192-1201
    • Silva Bezerra, F.1    Valenca, S.S.2    Lanzetti, M.3    Pimenta, W.A.4    Castro, P.5    Goncalves Koatz, V.L.6
  • 23
    • 33751415352 scopus 로고    scopus 로고
    • The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin
    • PID: 17102939, COI: 1:CAS:528:DC%2BD28Xht1eru7rK
    • Rakotoniaina, Z., P. Guerard, F. Lirussi, F. Goirand, L. Rochette, M. Dumas, et al. 2006. The protective effect of HMG-CoA reductase inhibitors against monocrotaline-induced pulmonary hypertension in the rat might not be a class effect: comparison of pravastatin and atorvastatin. Naunyn-Schmiedeberg's Archives of Pharmacology 374: 195–206.
    • (2006) Naunyn-Schmiedeberg's Archives of Pharmacology , vol.374 , pp. 195-206
    • Rakotoniaina, Z.1    Guerard, P.2    Lirussi, F.3    Goirand, F.4    Rochette, L.5    Dumas, M.6
  • 24
    • 33747073147 scopus 로고    scopus 로고
    • Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury
    • PID: 16922808, COI: 1:CAS:528:DC%2BD28Xps1Sntbg%3D
    • Yao, H.W., L.G. Mao, and J.P. Zhu. 2006. Protective effects of pravastatin in murine lipopolysaccharide-induced acute lung injury. Clinical and Experimental Pharmacology and Physiology 33: 793–7.
    • (2006) Clinical and Experimental Pharmacology and Physiology , vol.33 , pp. 793-797
    • Yao, H.W.1    Mao, L.G.2    Zhu, J.P.3
  • 25
    • 84865004276 scopus 로고    scopus 로고
    • Rosuvastatin promotes angiogenesis and reverses isoproterenol-induced acute myocardial infarction in rats: role of iNOS and VEGF
    • PID: 22732653, COI: 1:CAS:528:DC%2BC38XhtFeitLjN
    • Zaitone, S.A., and N.M. Abo-Gresha. 2012. Rosuvastatin promotes angiogenesis and reverses isoproterenol-induced acute myocardial infarction in rats: role of iNOS and VEGF. European Journal of Pharmacology 691: 134–42.
    • (2012) European Journal of Pharmacology , vol.691 , pp. 134-142
    • Zaitone, S.A.1    Abo-Gresha, N.M.2
  • 27
    • 0020550892 scopus 로고
    • Assay method for myeloperoxidase in human polymorphonuclear leukocytes
    • PID: 6312841, COI: 1:CAS:528:DyaL3sXks1KgtLs%3D
    • Suzuki, K., H. Ota, S. Sasagawa, T. Sakatani, and T. Fujikura. 1983. Assay method for myeloperoxidase in human polymorphonuclear leukocytes. Analytical Biochemistry 132: 345–52.
    • (1983) Analytical Biochemistry , vol.132 , pp. 345-352
    • Suzuki, K.1    Ota, H.2    Sasagawa, S.3    Sakatani, T.4    Fujikura, T.5
  • 29
    • 34247186655 scopus 로고    scopus 로고
    • Disruption of skeletal myocytes initiates superoxide release: contribution of NADPH oxidase
    • PID: 17438461, COI: 1:CAS:528:DC%2BD2sXls1GksLo%3D
    • Kerkweg, U., F. Petrat, H.G. Korth, and H. de Groot. 2007. Disruption of skeletal myocytes initiates superoxide release: contribution of NADPH oxidase. Shock 27: 552–8.
    • (2007) Shock , vol.27 , pp. 552-558
    • Kerkweg, U.1    Petrat, F.2    Korth, H.G.3    de Groot, H.4
  • 30
    • 0023080351 scopus 로고
    • Assays for superoxide dismutase
    • PID: 3033431, COI: 1:CAS:528:DyaL1cXptVansw%3D%3D
    • Bannister, J.V., and L. Calabrese. 1987. Assays for superoxide dismutase. Methods of Biochemical Analysis 32: 279–312.
    • (1987) Methods of Biochemical Analysis , vol.32 , pp. 279-312
    • Bannister, J.V.1    Calabrese, L.2
  • 32
    • 34548851693 scopus 로고    scopus 로고
    • Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method
    • PID: 17406579, COI: 1:CAS:528:DC%2BD2sXhtFGjtLzO
    • Rahman, I., A. Kode, and S.K. Biswas. 2006. Assay for quantitative determination of glutathione and glutathione disulfide levels using enzymatic recycling method. Nature Protocols 1: 3159–65.
    • (2006) Nature Protocols , vol.1 , pp. 3159-3165
    • Rahman, I.1    Kode, A.2    Biswas, S.K.3
  • 33
  • 34
    • 0029114548 scopus 로고
    • Quantification of lipid peroxidation in tissue extracts based on Fe(III)xylenol orange complex formation
    • PID: 7557541, COI: 1:CAS:528:DyaK2MXntFGnur8%3D
    • Hermes-Lima, M., W.G. Willmore, and K.B. Storey. 1995. Quantification of lipid peroxidation in tissue extracts based on Fe(III)xylenol orange complex formation. Free Radical Biology and Medicine 19: 271–80.
    • (1995) Free Radical Biology and Medicine , vol.19 , pp. 271-280
    • Hermes-Lima, M.1    Willmore, W.G.2    Storey, K.B.3
  • 35
    • 33846338938 scopus 로고    scopus 로고
    • Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model
    • PID: 17169357, COI: 1:CAS:528:DC%2BD2sXhtVKntrc%3D
    • Kim, D.Y., S.Y. Ryu, J.E. Lim, Y.S. Lee, and J.Y. Ro. 2007. Anti-inflammatory mechanism of simvastatin in mouse allergic asthma model. European Journal of Pharmacology 557: 76–86.
    • (2007) European Journal of Pharmacology , vol.557 , pp. 76-86
    • Kim, D.Y.1    Ryu, S.Y.2    Lim, J.E.3    Lee, Y.S.4    Ro, J.Y.5
  • 36
    • 38049034068 scopus 로고    scopus 로고
    • Pleiotropic effects of statin therapy: molecular mechanisms and clinical results
    • PID: 18068482, COI: 1:CAS:528:DC%2BD1cXptlehsg%3D%3D
    • Wang, C.Y., P.Y. Liu, and J.K. Liao. 2008. Pleiotropic effects of statin therapy: molecular mechanisms and clinical results. Trends in Molecular Medicine 14: 37–44.
    • (2008) Trends in Molecular Medicine , vol.14 , pp. 37-44
    • Wang, C.Y.1    Liu, P.Y.2    Liao, J.K.3
  • 38
    • 59649092524 scopus 로고    scopus 로고
    • The in vitro effects of cigarette smoke on fatty acid metabolism are partially counteracted by simvastatin
    • PID: 19128950, COI: 1:CAS:528:DC%2BD1MXitVOltbg%3D
    • Rise, P., S. Ghezzi, C. Manzoni, C. Colombo, and C. Galli. 2009. The in vitro effects of cigarette smoke on fatty acid metabolism are partially counteracted by simvastatin. Prostaglandins, Leukotrienes, and Essential Fatty Acids 80: 71–5.
    • (2009) Prostaglandins, Leukotrienes, and Essential Fatty Acids , vol.80 , pp. 71-75
    • Rise, P.1    Ghezzi, S.2    Manzoni, C.3    Colombo, C.4    Galli, C.5
  • 39
    • 0242305121 scopus 로고    scopus 로고
    • Significant involvement of CCL2 (MCP-1) in inflammatory disorders of the lung
    • PID: 12851645, COI: 1:CAS:528:DC%2BD3sXlt1WltLo%3D
    • Rose Jr., C.E., S.S. Sung, and S.M. Fu. 2003. Significant involvement of CCL2 (MCP-1) in inflammatory disorders of the lung. Microcirculation 10: 273–88.
    • (2003) Microcirculation , vol.10 , pp. 273-288
    • Rose, C.E.1    Sung, S.S.2    Fu, S.M.3
  • 40
    • 43949112933 scopus 로고    scopus 로고
    • HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation
    • PID: 18503891, COI: 1:CAS:528:DC%2BD1cXmt12rtb0%3D
    • Fildes, J.E., S.M. Shaw, A. Mitsidou, K. Rogacev, C.T. Leonard, S.G. Williams, et al. 2008. HMG-CoA reductase inhibitors deplete circulating classical and non-classical monocytes following human heart transplantation. Transplant Immunology 19: 152–7.
    • (2008) Transplant Immunology , vol.19 , pp. 152-157
    • Fildes, J.E.1    Shaw, S.M.2    Mitsidou, A.3    Rogacev, K.4    Leonard, C.T.5    Williams, S.G.6
  • 42
    • 61349091828 scopus 로고    scopus 로고
    • Statins inhibit C-reactive protein-induced chemokine secretion, ICAM-1 upregulation and chemotaxis in adherent human monocytes
    • COI: 1:CAS:528:DC%2BD1MXisVSmsbc%3D
    • Montecucco, F., F. Burger, G. Pelli, N.K. Poku, C. Berlier, S. Steffens, et al. 2009. Statins inhibit C-reactive protein-induced chemokine secretion, ICAM-1 upregulation and chemotaxis in adherent human monocytes. Rheumatology (Oxford) 48: 233–42.
    • (2009) Rheumatology (Oxford) , vol.48 , pp. 233-242
    • Montecucco, F.1    Burger, F.2    Pelli, G.3    Poku, N.K.4    Berlier, C.5    Steffens, S.6
  • 45
    • 0026661124 scopus 로고
    • Activation of the human neutrophil 5-lipoxygenase by leukotriene B4
    • PID: 1330161, COI: 1:CAS:528:DyaK38Xls12nsrw%3D
    • McDonald, P.P., S.R. McColl, P.H. Naccache, and P. Borgeat. 1992. Activation of the human neutrophil 5-lipoxygenase by leukotriene B4. British Journal of Pharmacology 107: 226–32.
    • (1992) British Journal of Pharmacology , vol.107 , pp. 226-232
    • McDonald, P.P.1    McColl, S.R.2    Naccache, P.H.3    Borgeat, P.4
  • 46
    • 80053321927 scopus 로고    scopus 로고
    • Neutrophils cascading their way to inflammation
    • PID: 21839682, COI: 1:CAS:528:DC%2BC3MXht1GrsLfJ
    • Sadik, C.D., N.D. Kim, and A.D. Luster. 2011. Neutrophils cascading their way to inflammation. Trends in Immunology 32: 452–60.
    • (2011) Trends in Immunology , vol.32 , pp. 452-460
    • Sadik, C.D.1    Kim, N.D.2    Luster, A.D.3
  • 47
    • 84870702582 scopus 로고    scopus 로고
    • No effect of high-dose atorvastatin on leukotriene B(4) formation from neutrophils in patients treated with coronary bypass surgery: a randomized placebo-controlled double-blinded trial with a crossover design
    • PID: 23063168, COI: 1:CAS:528:DC%2BC38XhsV2qt7nK
    • Lysgaard, C., M.S. Nielsen, J.H. Christensen, S. Lundbye-Christensen, S. Riahi, and E.B. Schmidt. 2012. No effect of high-dose atorvastatin on leukotriene B(4) formation from neutrophils in patients treated with coronary bypass surgery: a randomized placebo-controlled double-blinded trial with a crossover design. Prostaglandins, Leukotrienes, and Essential Fatty Acids 87: 185–8.
    • (2012) Prostaglandins, Leukotrienes, and Essential Fatty Acids , vol.87 , pp. 185-188
    • Lysgaard, C.1    Nielsen, M.S.2    Christensen, J.H.3    Lundbye-Christensen, S.4    Riahi, S.5    Schmidt, E.B.6
  • 48
    • 0035261388 scopus 로고    scopus 로고
    • Inhibition of inducible nitric oxide synthase (iNOS) prevents lung neutrophil deposition and damage in burned rats
    • PID: 11220644, COI: 1:STN:280:DC%2BD3M3isValtQ%3D%3D
    • Chen, L.W., C.M. Hsu, J.S. Wang, H.L. Chen, and J.S. Chen. 2001. Inhibition of inducible nitric oxide synthase (iNOS) prevents lung neutrophil deposition and damage in burned rats. Shock 15: 151–6.
    • (2001) Shock , vol.15 , pp. 151-156
    • Chen, L.W.1    Hsu, C.M.2    Wang, J.S.3    Chen, H.L.4    Chen, J.S.5
  • 49
    • 0033459527 scopus 로고    scopus 로고
    • In stable lung transplant recipients, exhaled nitric oxide levels positively correlate with airway neutrophilia and bronchial epithelial iNOS
    • PID: 10588634, COI: 1:STN:280:DC%2BD3c%2Fls1emuw%3D%3D
    • Gabbay, E., E. Haydn Walters, B. Orsida, H. Whitford, C. Ward, T.C. Kotsimbos, et al. 1999. In stable lung transplant recipients, exhaled nitric oxide levels positively correlate with airway neutrophilia and bronchial epithelial iNOS. American Journal of Respiratory and Critical Care Medicine 160: 2093–9.
    • (1999) American Journal of Respiratory and Critical Care Medicine , vol.160 , pp. 2093-2099
    • Gabbay, E.1    Haydn Walters, E.2    Orsida, B.3    Whitford, H.4    Ward, C.5    Kotsimbos, T.C.6
  • 50
    • 3042566974 scopus 로고    scopus 로고
    • Selective inducible nitric oxide synthase (iNOS) inhibition attenuates remote acute lung injury in a model of ruptured abdominal aortic aneurysm
    • PID: 15234218, COI: 1:CAS:528:DC%2BD2cXlsVSgsb4%3D
    • Harkin, D.W., B.B. Rubin, A. Romaschin, and T.F. Lindsay. 2004. Selective inducible nitric oxide synthase (iNOS) inhibition attenuates remote acute lung injury in a model of ruptured abdominal aortic aneurysm. Journal of Surgical Research 120: 230–41.
    • (2004) Journal of Surgical Research , vol.120 , pp. 230-241
    • Harkin, D.W.1    Rubin, B.B.2    Romaschin, A.3    Lindsay, T.F.4
  • 51
    • 1942471912 scopus 로고    scopus 로고
    • Nitric oxide generated by iNOS reduces deformability of Lewis lung carcinoma cells
    • PID: 15072593, COI: 1:CAS:528:DC%2BD2cXks1yks78%3D
    • Igawa, S., I. Hayashi, N. Tanaka, H. Hiruma, M. Majima, T. Kawakami, et al. 2004. Nitric oxide generated by iNOS reduces deformability of Lewis lung carcinoma cells. Cancer Science 95: 342–7.
    • (2004) Cancer Science , vol.95 , pp. 342-347
    • Igawa, S.1    Hayashi, I.2    Tanaka, N.3    Hiruma, H.4    Majima, M.5    Kawakami, T.6
  • 52
    • 0034810765 scopus 로고    scopus 로고
    • Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia
    • PID: 11341781, COI: 1:CAS:528:DC%2BD3MXjt1GntL0%3D
    • Wang, L.F., S. Mehta, S. Weicker, J.A. Scott, M. Joseph, H.M. Razavi, et al. 2001. Relative contribution of hemopoietic and pulmonary parenchymal cells to lung inducible nitric oxide synthase (inos) activity in murine endotoxemia. Biochemical and Biophysical Research Communications 283: 694–9.
    • (2001) Biochemical and Biophysical Research Communications , vol.283 , pp. 694-699
    • Wang, L.F.1    Mehta, S.2    Weicker, S.3    Scott, J.A.4    Joseph, M.5    Razavi, H.M.6
  • 53
    • 62249181657 scopus 로고    scopus 로고
    • Reactive oxygen species- and nitric oxide-mediated lung inflammation and mitochondrial dysfunction in wild-type and iNOS-deficient mice exposed to diesel exhaust particles
    • COI: 1:CAS:528:DC%2BD1MXltlagtLo%3D
    • Zhao, H., J.K. Ma, M.W. Barger, R.R. Mercer, L. Millecchia, D. Schwegler-Berry, et al. 2009. Reactive oxygen species- and nitric oxide-mediated lung inflammation and mitochondrial dysfunction in wild-type and iNOS-deficient mice exposed to diesel exhaust particles. Journal of Toxicology and Environmental Health A 72: 560–70.
    • (2009) Journal of Toxicology and Environmental Health A , vol.72 , pp. 560-570
    • Zhao, H.1    Ma, J.K.2    Barger, M.W.3    Mercer, R.R.4    Millecchia, L.5    Schwegler-Berry, D.6
  • 56
    • 79952232802 scopus 로고    scopus 로고
    • Hemorrhagic shock activates lung endothelial reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase via neutrophil NADPH oxidase
    • PID: 20418360, COI: 1:CAS:528:DC%2BC3MXot1Gqu7s%3D
    • Xiang, M., L. Yin, Y. Li, G. Xiao, Y. Vodovotz, T.R. Billiar, et al. 2011. Hemorrhagic shock activates lung endothelial reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase via neutrophil NADPH oxidase. American Journal of Respiratory Cell and Molecular Biology 44: 333–40.
    • (2011) American Journal of Respiratory Cell and Molecular Biology , vol.44 , pp. 333-340
    • Xiang, M.1    Yin, L.2    Li, Y.3    Xiao, G.4    Vodovotz, Y.5    Billiar, T.R.6
  • 61
    • 77956257800 scopus 로고    scopus 로고
    • Oxidative stress: acute and progressive lung injury
    • PID: 20716283, COI: 1:CAS:528:DC%2BC3cXhtFKjsLrJ
    • Ward, P.A. 2010. Oxidative stress: acute and progressive lung injury. Annals of the New York Academy of Sciences 1203: 53–9.
    • (2010) Annals of the New York Academy of Sciences , vol.1203 , pp. 53-59
    • Ward, P.A.1
  • 62
    • 0027291544 scopus 로고
    • Cigarette smoking and oxidative damage in the lung
    • PID: 8512254, COI: 1:STN:280:DyaK3s3ptValtA%3D%3D
    • Chow, C.K. 1993. Cigarette smoking and oxidative damage in the lung. Annals of the New York Academy of Sciences 686: 289–98.
    • (1993) Annals of the New York Academy of Sciences , vol.686 , pp. 289-298
    • Chow, C.K.1
  • 63
    • 33845741277 scopus 로고    scopus 로고
    • Repair of the oxidative DNA damage 8-oxoguanine as a biomarker for lung cancer risk
    • PID: 17192041, COI: 1:CAS:528:DC%2BD28XhsFejs7k%3D
    • Paz-Elizur, T., M. Krupsky, D. Elinger, E. Schechtman, and Z. Livneh. 2005. Repair of the oxidative DNA damage 8-oxoguanine as a biomarker for lung cancer risk. Cancer Biomarkers 1: 201–5.
    • (2005) Cancer Biomarkers , vol.1 , pp. 201-205
    • Paz-Elizur, T.1    Krupsky, M.2    Elinger, D.3    Schechtman, E.4    Livneh, Z.5
  • 65
    • 84055182538 scopus 로고    scopus 로고
    • Myocardial redox state predicts in-hospital clinical outcome after cardiac surgery effects of short-term pre-operative statin treatment
    • PID: 22192670, COI: 1:CAS:528:DC%2BC38Xit1Wjsbs%3D
    • Antoniades, C., M. Demosthenous, S. Reilly, M. Margaritis, M.H. Zhang, A. Antonopoulos, et al. 2012. Myocardial redox state predicts in-hospital clinical outcome after cardiac surgery effects of short-term pre-operative statin treatment. Journal of the American College of Cardiology 59: 60–70.
    • (2012) Journal of the American College of Cardiology , vol.59 , pp. 60-70
    • Antoniades, C.1    Demosthenous, M.2    Reilly, S.3    Margaritis, M.4    Zhang, M.H.5    Antonopoulos, A.6
  • 67
    • 41449092262 scopus 로고    scopus 로고
    • Effects of the statin antihyperlipidemic agent simvastatin on grass shrimp, Palaemonetes pugio
    • PID: 18214920, COI: 1:CAS:528:DC%2BD1cXkt1CmsLs%3D
    • Key, P.B., J. Hoguet, L.A. Reed, K.W. Chung, and M.H. Fulton. 2008. Effects of the statin antihyperlipidemic agent simvastatin on grass shrimp, Palaemonetes pugio. Environmental Toxicology 23: 153–60.
    • (2008) Environmental Toxicology , vol.23 , pp. 153-160
    • Key, P.B.1    Hoguet, J.2    Reed, L.A.3    Chung, K.W.4    Fulton, M.H.5
  • 68
    • 58349097915 scopus 로고    scopus 로고
    • Pretreatment with statin attenuates the cardiotoxicity of doxorubicin in mice
    • PID: 19147586, COI: 1:CAS:528:DC%2BD1MXltFSgug%3D%3D
    • Riad, A., S. Bien, D. Westermann, P.M. Becher, K. Loya, U. Landmesser, et al. 2009. Pretreatment with statin attenuates the cardiotoxicity of doxorubicin in mice. Cancer Research 69: 695–9.
    • (2009) Cancer Research , vol.69 , pp. 695-699
    • Riad, A.1    Bien, S.2    Westermann, D.3    Becher, P.M.4    Loya, K.5    Landmesser, U.6
  • 69
    • 79953238469 scopus 로고    scopus 로고
    • Are all statins the same? Focus on the efficacy and tolerability of pitavastatin
    • PID: 21446776
    • da Silva, P.M. 2011. Are all statins the same? Focus on the efficacy and tolerability of pitavastatin. American Journal of Cardiovascular Drugs 11: 93–107.
    • (2011) American Journal of Cardiovascular Drugs , vol.11 , pp. 93-107
    • da Silva, P.M.1
  • 70
    • 84870463778 scopus 로고    scopus 로고
    • Inhibition of MCP-1/CCR2 signaling pathway is involved in synergistic inhibitory effects of irbesartan with rosuvastatin on vascular remodeling
    • PID: 23107893, COI: 1:CAS:528:DC%2BC3sXhtFOhsb4%3D
    • Ohshima, K., M. Mogi, H. Nakaoka, F. Jing, J. Iwanami, L.J. Min, et al. 2012. Inhibition of MCP-1/CCR2 signaling pathway is involved in synergistic inhibitory effects of irbesartan with rosuvastatin on vascular remodeling. Journal of the American Society of Hypertension 6: 375–84.
    • (2012) Journal of the American Society of Hypertension , vol.6 , pp. 375-384
    • Ohshima, K.1    Mogi, M.2    Nakaoka, H.3    Jing, F.4    Iwanami, J.5    Min, L.J.6
  • 71
    • 0029970957 scopus 로고    scopus 로고
    • Lipoxygenase metabolites induced expression of adhesion molecules and transendothelial migration of monocyte-like HL-60 cells is linked to protein kinase C activation
    • PID: 8655602, COI: 1:CAS:528:DyaK28XjtFClsrY%3D
    • Sultana, C., Y. Shen, V. Rattan, and V.K. Kalra. 1996. Lipoxygenase metabolites induced expression of adhesion molecules and transendothelial migration of monocyte-like HL-60 cells is linked to protein kinase C activation. Journal of Cellular Physiology 167: 477–87.
    • (1996) Journal of Cellular Physiology , vol.167 , pp. 477-487
    • Sultana, C.1    Shen, Y.2    Rattan, V.3    Kalra, V.K.4
  • 72
    • 79954598418 scopus 로고    scopus 로고
    • Protective role of simvastatin on lung damage caused by burn and cotton smoke inhalation in rats
    • PID: 20452610, COI: 1:CAS:528:DC%2BC3MXkvFaqtrg%3D
    • Belli, S., O. Basaran, B.H. Ozdemir, S. Turkoglu, G. Karabay, A. Kut, et al. 2011. Protective role of simvastatin on lung damage caused by burn and cotton smoke inhalation in rats. Journal of Surgical Research 167: e283–90.
    • (2011) Journal of Surgical Research , vol.167 , pp. e283-e290
    • Belli, S.1    Basaran, O.2    Ozdemir, B.H.3    Turkoglu, S.4    Karabay, G.5    Kut, A.6
  • 74
    • 84862741653 scopus 로고    scopus 로고
    • Lipitor goes generic: business as usual or more big business?
    • PID: 22711082, W313
    • Gill, L., J. Santa, D.L. Peter, and J. Keehn. 2012. Lipitor goes generic: business as usual or more big business? Annals of Internal Medicine 156: 892–3. W313.
    • (2012) Annals of Internal Medicine , vol.156 , pp. 892-893
    • Gill, L.1    Santa, J.2    Peter, D.L.3    Keehn, J.4
  • 76
    • 29244490096 scopus 로고    scopus 로고
    • Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke
    • PID: 16368650
    • da Hora, K., S.S. Valenca, and L.C. Porto. 2005. Immunohistochemical study of tumor necrosis factor-alpha, matrix metalloproteinase-12, and tissue inhibitor of metalloproteinase-2 on alveolar macrophages of BALB/c mice exposed to short-term cigarette smoke. Experimental Lung Research 31: 759–70.
    • (2005) Experimental Lung Research , vol.31 , pp. 759-770
    • da Hora, K.1    Valenca, S.S.2    Porto, L.C.3
  • 79
    • 56449124233 scopus 로고    scopus 로고
    • Immunohistochemical study of lung remodeling in mice exposed to cigarette smoke*
    • PID: 19009211
    • Valenca, S.S., and L.C. Porto. 2008. Immunohistochemical study of lung remodeling in mice exposed to cigarette smoke*. Jornal Brasileiro de Pneumologia 34: 787–95.
    • (2008) Jornal Brasileiro de Pneumologia , vol.34 , pp. 787-795
    • Valenca, S.S.1    Porto, L.C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.