Neuroprotection by the PARP inhibitor PJ34 modulates cerebral and circulating RAGE levels in rats exposed to focal brain ischemia

European Journal of Pharmacology

Volumn 744, Issue , 2014, Pages 91-97

  Greco, Rosaria ^a   Tassorelli, Cristina ^a,b   Stefania Mangione, Antonina ^a   Levandis, Giovanna ^a   Certo, Michelangelo ^c   Nappi, Giuseppe ^a   Bagetta, Giacinto ^c   Blandini, Fabio ^a   Amantea, Diana ^c  

^a C MONDINO NATIONAL NEUROLOGICAL INSTITUTE   (Italy)

^b UNIVERSITY OF PAVIA   (Italy)

^c UNIVERSITY OF CALABRIA   (Italy)

Author keywords

Cerebral ischemia; Full length; MCAo; PARP inhibition; RAGE; sRAGE

Indexed keywords

ADVANCED GLYCATION END PRODUCT RECEPTOR; N (5,6 DIHYDRO 6 OXO 2 PHENANTHRIDINYL) 2 DIMETHYLAMINOACETAMIDE; ADVANCED GLYCATION END PRODUCT; ADVANCED GLYCOSYLATION END-PRODUCT RECEPTOR; ENZYME INHIBITOR; IMMUNOGLOBULIN RECEPTOR; N-(OXO-5,6-DIHYDROPHENANTHRIDIN-2-YL)-N,N-DIMETHYLACETAMIDE HYDROCHLORIDE; NEUROPROTECTIVE AGENT; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PHENANTHRENE DERIVATIVE;

ADULT; ALTERNATIVE RNA SPLICING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN ISCHEMIA; CELL PROTECTION; CELL SURFACE; CONTROLLED STUDY; CORPUS STRIATUM; FOCAL BRAIN ISCHEMIA; FRONTOPARIETAL CORTEX; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; NEUROMODULATION; NEUROPROTECTION; NONHUMAN; PARIETAL CORTEX; PROTEIN BINDING; PROTEIN BLOOD LEVEL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; RAT; REPERFUSION; SIGNAL TRANSDUCTION; ANIMAL; ANTAGONISTS AND INHIBITORS; BRAIN; DRUG EFFECTS; INFARCTION, MIDDLE CEREBRAL ARTERY; METABOLISM; NERVE CELL; STROKE; WISTAR RAT;

ANIMALS; BRAIN; BRAIN ISCHEMIA; ENZYME INHIBITORS; GLYCOSYLATION END PRODUCTS, ADVANCED; INFARCTION, MIDDLE CEREBRAL ARTERY; MALE; NEURONS; NEUROPROTECTIVE AGENTS; PHENANTHRENES; POLY(ADP-RIBOSE) POLYMERASES; RATS; RATS, WISTAR; RECEPTORS, IMMUNOLOGIC; STROKE;

EID: 84918791137     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.10.006     Document Type: Article

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