Dynein dysfunction disrupts β-amyloid clearance in astrocytes through endocytic disturbances

NeuroReport

Volumn 25, Issue 7, 2014, Pages 514-520

  Kimura, Nobuyuki ^a,b   Okabayashi, Sachi ^b,c   Ono, Fumiko ^b,c  

^a NATIONAL CENTER FOR GERIATRICS AND GERONTOLOGY   (Japan)

^b NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^c The Corporation for Production and Research of Laboratory Primates   (Japan)

Author keywords

Aging; Alzheimer's disease; Astrocytes; Dynein; Endocytosis; amyloid protein

Indexed keywords

AMYLOID BETA PROTEIN; DYNEIN ADENOSINE TRIPHOSPHATASE; RAB7 PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR; DYNACTIN; GLIAL FIBRILLARY ACIDIC PROTEIN; MICROTUBULE ASSOCIATED PROTEIN; SMALL INTERFERING RNA; VESICULAR TRANSPORT PROTEIN;

AGED; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL FUNCTION; CONTROLLED STUDY; ENDOCYTOSIS; ENDOSOME; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; INTRACELLULAR SIGNALING; MACACA FASCICULARIS; NONHUMAN; PATHOLOGY; PRIORITY JOURNAL; RAT; AGING; ANIMAL; BRAIN; CELL CULTURE; CYTOLOGY; ENZYME LINKED IMMUNOSORBENT ASSAY; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT; ULTRASTRUCTURE;

AGING; AMYLOID BETA-PEPTIDES; ANIMALS; ASTROCYTES; BRAIN; BRAIN-DERIVED NEUROTROPHIC FACTOR; CELLS, CULTURED; DYNEINS; ENDOCYTOSIS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GLIAL FIBRILLARY ACIDIC PROTEIN; MACACA FASCICULARIS; MICROTUBULE-ASSOCIATED PROTEINS; RATS, SPRAGUE-DAWLEY; RNA, SMALL INTERFERING; VESICULAR TRANSPORT PROTEINS;

EID: 84918788847     PISSN: 09594965     EISSN: 1473558X     Source Type: Journal    
DOI: 10.1097/WNR.0000000000000124     Document Type: Article

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