Dynein dysfunction disrupts intracellular vesicle trafficking bidirectionally and perturbs synaptic vesicle docking via endocytic disturbances: A potential mechanism underlying age-dependent impairment of cognitive function

American Journal of Pathology

Volumn 180, Issue 2, 2012, Pages 550-561

  Kimura, Nobuyuki ^a   Okabayashi, Sachi ^a,b   Ono, Fumiko ^a,b  

^a NATIONAL INSTITUTE OF BIOMEDICAL INNOVATION   (Japan)

^b The Corporation for Production and Research of Laboratory Primates   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; CYTOPLASMIC DYNEIN; NEUROFILAMENT PROTEIN; RAB PROTEIN;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN CELL; CELL VACUOLE; COGNITIVE DEFECT; ENDOCYTOSIS; FEMALE; MACACA FASCICULARIS; NERVE FIBER TRANSPORT; NEUROFILAMENT; NONHUMAN; PRIORITY JOURNAL; RAT; SYNAPSE VESICLE;

ADENINE; AGE FACTORS; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; ANIMALS; BIOLOGICAL TRANSPORT; BRAIN CHEMISTRY; CEREBRAL CORTEX; COGNITION DISORDERS; DYNEINS; ENDOCYTOSIS; ENZYME INHIBITORS; MACACA FASCICULARIS; MICROTUBULE-ASSOCIATED PROTEINS; MICROTUBULES; NEUROFILAMENT PROTEINS; NEURONS; RAB GTP-BINDING PROTEINS; RECEPTOR, TRKB; SYNAPTIC VESICLES;

EID: 84856021939     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.10.037     Document Type: Article

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