메뉴 건너뛰기




Volumn 24, Issue 11, 2014, Pages 1836-1849

Re-evaluating the PCP challenge as a pre-clinical model of impaired cognitive flexibility in schizophrenia

Author keywords

NMDA R; Reversal learning; Schizophrenia; Touch screen; Visual discrimination

Indexed keywords

PHENCYCLIDINE;

EID: 84918784680     PISSN: 0924977X     EISSN: 18737862     Source Type: Journal    
DOI: 10.1016/j.euroneuro.2014.08.012     Document Type: Article
Times cited : (23)

References (47)
  • 1
    • 0032527894 scopus 로고    scopus 로고
    • Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine
    • Adams B., Moghaddam B. Corticolimbic dopamine neurotransmission is temporally dissociated from the cognitive and locomotor effects of phencyclidine. J. Neurosci. 1998, 18:5545-5554.
    • (1998) J. Neurosci. , vol.18 , pp. 5545-5554
    • Adams, B.1    Moghaddam, B.2
  • 2
    • 0034212645 scopus 로고    scopus 로고
    • Medial frontal cortex mediates perceptual attentional set shifting in the rat
    • Birrell J.M., Brown V.J. Medial frontal cortex mediates perceptual attentional set shifting in the rat. J. Neurosci. 2000, 20:4320-4324.
    • (2000) J. Neurosci. , vol.20 , pp. 4320-4324
    • Birrell, J.M.1    Brown, V.J.2
  • 3
    • 84872477442 scopus 로고    scopus 로고
    • Expression of NMDA receptor-dependent LTP in the hippocampus: bridging the divide
    • Bliss T.V., Collingridge G.L. Expression of NMDA receptor-dependent LTP in the hippocampus: bridging the divide. Mol. Brain 2013, 6:5.
    • (2013) Mol. Brain , vol.6 , pp. 5
    • Bliss, T.V.1    Collingridge, G.L.2
  • 4
    • 0037676149 scopus 로고    scopus 로고
    • Orbital prefrontal cortex and guidance of instrumental behaviour in rats under reversal conditions
    • Bohn I., Giertler C., Hauber W. Orbital prefrontal cortex and guidance of instrumental behaviour in rats under reversal conditions. Behav. Brain Res. 2003, 143:49-56.
    • (2003) Behav. Brain Res. , vol.143 , pp. 49-56
    • Bohn, I.1    Giertler, C.2    Hauber, W.3
  • 5
    • 77953621538 scopus 로고    scopus 로고
    • Effects of Subchronic Phencyclidine (PCP) treatment on social behaviors, and operant discrimination and reversal learning in C57BL/6J mice
    • Brigman J.L., Ihne J., Saksida L.M., Bussey T.J., Holmes A. Effects of Subchronic Phencyclidine (PCP) treatment on social behaviors, and operant discrimination and reversal learning in C57BL/6J mice. Front Behav. Neurosci. 2009, 3:2.
    • (2009) Front Behav. Neurosci. , vol.3 , pp. 2
    • Brigman, J.L.1    Ihne, J.2    Saksida, L.M.3    Bussey, T.J.4    Holmes, A.5
  • 7
    • 33947628658 scopus 로고    scopus 로고
    • Rats depend on habit memory for discrimination learning and retention
    • Broadbent N.J., Squire L.R., Clark R.E. Rats depend on habit memory for discrimination learning and retention. Learn. Mem. 2007, 14:145-151.
    • (2007) Learn. Mem. , vol.14 , pp. 145-151
    • Broadbent, N.J.1    Squire, L.R.2    Clark, R.E.3
  • 8
    • 0030828693 scopus 로고    scopus 로고
    • Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat
    • Bussey T.J., Muir J.L., Everitt B.J., Robbins T.W. Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat. Behav. Neurosci. 1997, 111:920-936.
    • (1997) Behav. Neurosci. , vol.111 , pp. 920-936
    • Bussey, T.J.1    Muir, J.L.2    Everitt, B.J.3    Robbins, T.W.4
  • 9
    • 0030731499 scopus 로고    scopus 로고
    • Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: implications for the neurobiology of emotion
    • Bussey T.J., Everitt B.J., Robbins T.W. Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: implications for the neurobiology of emotion. Behav. Neurosci. 1997, 111:908-919.
    • (1997) Behav. Neurosci. , vol.111 , pp. 908-919
    • Bussey, T.J.1    Everitt, B.J.2    Robbins, T.W.3
  • 10
    • 0034660584 scopus 로고    scopus 로고
    • Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat
    • Bussey T.J., Duck J., Muir J.L., Aggleton J.P. Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat. Behav. Brain Res. 2000, 111:187-202.
    • (2000) Behav. Brain Res. , vol.111 , pp. 187-202
    • Bussey, T.J.1    Duck, J.2    Muir, J.L.3    Aggleton, J.P.4
  • 11
    • 33645500829 scopus 로고    scopus 로고
    • Perirhinal cortex and feature-ambiguous discriminations
    • Bussey T.J., Saksida L.M., Murray E.A. Perirhinal cortex and feature-ambiguous discriminations. Learn. Mem. 2006, 13:103-105.
    • (2006) Learn. Mem. , vol.13 , pp. 103-105
    • Bussey, T.J.1    Saksida, L.M.2    Murray, E.A.3
  • 13
    • 0023948389 scopus 로고
    • Frequency-dependent N-methyl-D-aspartate receptor-mediated synaptic transmission in rat hippocampus
    • Collingridge G.L., Herron C.E., Lester R.A. Frequency-dependent N-methyl-D-aspartate receptor-mediated synaptic transmission in rat hippocampus. J. Physiol. 1988, 399:301-312.
    • (1988) J. Physiol. , vol.399 , pp. 301-312
    • Collingridge, G.L.1    Herron, C.E.2    Lester, R.A.3
  • 14
    • 0023948388 scopus 로고
    • Synaptic activation of N-methyl-D-aspartate receptors in the Schaffer collateral-commissural pathway of rat hippocampus
    • Collingridge G.L., Herron C.E., Lester R.A. Synaptic activation of N-methyl-D-aspartate receptors in the Schaffer collateral-commissural pathway of rat hippocampus. J. Physiol. 1988, 399:283-300.
    • (1988) J. Physiol. , vol.399 , pp. 283-300
    • Collingridge, G.L.1    Herron, C.E.2    Lester, R.A.3
  • 15
    • 34347369304 scopus 로고    scopus 로고
    • Reversal of PCP-induced learning and memory deficits in the Morris' water maze by sertindole and other antipsychotics
    • Didriksen M., Skarsfeldt T., Arnt J. Reversal of PCP-induced learning and memory deficits in the Morris' water maze by sertindole and other antipsychotics. Psychopharmacology (Berl) 2007, 193:225-233.
    • (2007) Psychopharmacology (Berl) , vol.193 , pp. 225-233
    • Didriksen, M.1    Skarsfeldt, T.2    Arnt, J.3
  • 16
    • 77957335007 scopus 로고    scopus 로고
    • A within-subject cognitive battery in the rat: differential effects of NMDA receptor antagonists
    • Dix S., Gilmour G., Potts S., Smith J.W., Tricklebank M. A within-subject cognitive battery in the rat: differential effects of NMDA receptor antagonists. Psychopharmacology (Berl) 2010, 212:227-242.
    • (2010) Psychopharmacology (Berl) , vol.212 , pp. 227-242
    • Dix, S.1    Gilmour, G.2    Potts, S.3    Smith, J.W.4    Tricklebank, M.5
  • 17
    • 17744365167 scopus 로고    scopus 로고
    • Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia
    • Egerton A., Reid L., McKerchar C.E., Morris B.J., Pratt J.A. Impairment in perceptual attentional set-shifting following PCP administration: a rodent model of set-shifting deficits in schizophrenia. Psychopharmacology (Berl) 2005, 179:77-84.
    • (2005) Psychopharmacology (Berl) , vol.179 , pp. 77-84
    • Egerton, A.1    Reid, L.2    McKerchar, C.E.3    Morris, B.J.4    Pratt, J.A.5
  • 18
    • 43049083311 scopus 로고    scopus 로고
    • Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats
    • Egerton A., Reid L., McGregor S., Cochran S.M., Morris B.J., Pratt J.A. Subchronic and chronic PCP treatment produces temporally distinct deficits in attentional set shifting and prepulse inhibition in rats. Psychopharmacology (Berl) 2008, 198:37-49.
    • (2008) Psychopharmacology (Berl) , vol.198 , pp. 37-49
    • Egerton, A.1    Reid, L.2    McGregor, S.3    Cochran, S.M.4    Morris, B.J.5    Pratt, J.A.6
  • 20
    • 84866347172 scopus 로고    scopus 로고
    • The mGlu(5) positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat
    • Gastambide F., Gilmour G., Robbins T.W., Tricklebank M.D. The mGlu(5) positive allosteric modulator LSN2463359 differentially modulates motor, instrumental and cognitive effects of NMDA receptor antagonists in the rat. Neuropharmacology 2013, 64:240-247.
    • (2013) Neuropharmacology , vol.64 , pp. 240-247
    • Gastambide, F.1    Gilmour, G.2    Robbins, T.W.3    Tricklebank, M.D.4
  • 23
    • 72649104250 scopus 로고    scopus 로고
    • Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms
    • Idris N., Neill J., Grayson B., Bang-Andersen B., Witten L.M., Brennum L.T., Arnt J. Sertindole improves sub-chronic PCP-induced reversal learning and episodic memory deficits in rodents: involvement of 5-HT(6) and 5-HT (2A) receptor mechanisms. Psychopharmacology (Berl) 2010, 208:23-36.
    • (2010) Psychopharmacology (Berl) , vol.208 , pp. 23-36
    • Idris, N.1    Neill, J.2    Grayson, B.3    Bang-Andersen, B.4    Witten, L.M.5    Brennum, L.T.6    Arnt, J.7
  • 24
    • 0035205333 scopus 로고    scopus 로고
    • Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats
    • Jentsch J.D., Taylor J.R. Impaired inhibition of conditioned responses produced by subchronic administration of phencyclidine to rats. Neuropsychopharmacology 2001, 24:66-74.
    • (2001) Neuropsychopharmacology , vol.24 , pp. 66-74
    • Jentsch, J.D.1    Taylor, J.R.2
  • 25
    • 84888040441 scopus 로고    scopus 로고
    • The role of the hippocampo-prefrontal cortex system in phencyclidine-induced psychosis: a model for schizophrenia
    • Jodo E. The role of the hippocampo-prefrontal cortex system in phencyclidine-induced psychosis: a model for schizophrenia. J. Physiol. Paris 2013.
    • (2013) J. Physiol. Paris
    • Jodo, E.1
  • 26
    • 77954086949 scopus 로고    scopus 로고
    • The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies
    • Klinkenberg I., Blokland A. The validity of scopolamine as a pharmacological model for cognitive impairment: a review of animal behavioral studies. Neurosci. Biobehav. Rev. 2010, 34:1307-1350.
    • (2010) Neurosci. Biobehav. Rev. , vol.34 , pp. 1307-1350
    • Klinkenberg, I.1    Blokland, A.2
  • 27
    • 0344393796 scopus 로고    scopus 로고
    • Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat
    • McAlonan K., Brown V.J. Orbital prefrontal cortex mediates reversal learning and not attentional set shifting in the rat. Behav. Brain Res. 2003, 146:97-103.
    • (2003) Behav. Brain Res. , vol.146 , pp. 97-103
    • McAlonan, K.1    Brown, V.J.2
  • 28
    • 0027245532 scopus 로고
    • A triple dissociation of memory systems: hippocampus, amygdala, and dorsal striatum
    • McDonald R.J., White N.M. A triple dissociation of memory systems: hippocampus, amygdala, and dorsal striatum. Behav. Neurosci. 1993, 107:3-22.
    • (1993) Behav. Neurosci. , vol.107 , pp. 3-22
    • McDonald, R.J.1    White, N.M.2
  • 29
    • 40849097398 scopus 로고    scopus 로고
    • A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats
    • McLean S.L., Beck J.P., Woolley M.L., Neill J.C. A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats. Behav. Brain Res. 2008, 189:152-158.
    • (2008) Behav. Brain Res. , vol.189 , pp. 152-158
    • McLean, S.L.1    Beck, J.P.2    Woolley, M.L.3    Neill, J.C.4
  • 30
    • 70349575345 scopus 로고    scopus 로고
    • Role of 5-HT receptor mechanisms in sub-chronic PCP-induced reversal learning deficits in the rat
    • McLean S.L., Woolley M.L., Thomas D., Neill J.C. Role of 5-HT receptor mechanisms in sub-chronic PCP-induced reversal learning deficits in the rat. Psychopharmacology (Berl) 2009, 206:403-414.
    • (2009) Psychopharmacology (Berl) , vol.206 , pp. 403-414
    • McLean, S.L.1    Woolley, M.L.2    Thomas, D.3    Neill, J.C.4
  • 31
    • 77955273672 scopus 로고    scopus 로고
    • Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat
    • McLean S.L., Neill J.C., Idris N.F., Marston H.M., Wong E.H., Shahid M. Effects of asenapine, olanzapine, and risperidone on psychotomimetic-induced reversal-learning deficits in the rat. Behav. Brain Res. 2010, 214:240-247.
    • (2010) Behav. Brain Res. , vol.214 , pp. 240-247
    • McLean, S.L.1    Neill, J.C.2    Idris, N.F.3    Marston, H.M.4    Wong, E.H.5    Shahid, M.6
  • 32
    • 79952364365 scopus 로고    scopus 로고
    • Activation of alpha7 nicotinic receptors improves phencyclidine-induced deficits in cognitive tasks in rats: implications for therapy of cognitive dysfunction in schizophrenia
    • McLean S.L., Grayson B., Idris N.F., Lesage A.S., Pemberton D.J., Mackie C., Neill J.C. Activation of alpha7 nicotinic receptors improves phencyclidine-induced deficits in cognitive tasks in rats: implications for therapy of cognitive dysfunction in schizophrenia. Eur. Neuropsychopharmacol. 2011, 21:333-343.
    • (2011) Eur. Neuropsychopharmacol. , vol.21 , pp. 333-343
    • McLean, S.L.1    Grayson, B.2    Idris, N.F.3    Lesage, A.S.4    Pemberton, D.J.5    Mackie, C.6    Neill, J.C.7
  • 33
    • 84865025138 scopus 로고    scopus 로고
    • PNU-120596, a positive allosteric modulator of alpha7 nicotinic acetylcholine receptors, reverses a sub-chronic phencyclidine-induced cognitive deficit in the attentional set-shifting task in female rats
    • McLean S.L., Idris N.F., Grayson B., Gendle D.F., Mackie C., Lesage A.S., Pemberton D.J., Neill J.C. PNU-120596, a positive allosteric modulator of alpha7 nicotinic acetylcholine receptors, reverses a sub-chronic phencyclidine-induced cognitive deficit in the attentional set-shifting task in female rats. J. Psychopharmacol. 2012, 26:1265-1270.
    • (2012) J. Psychopharmacol. , vol.26 , pp. 1265-1270
    • McLean, S.L.1    Idris, N.F.2    Grayson, B.3    Gendle, D.F.4    Mackie, C.5    Lesage, A.S.6    Pemberton, D.J.7    Neill, J.C.8
  • 34
    • 67549096690 scopus 로고    scopus 로고
    • A new touchscreen test of pattern separation: effect of hippocampal lesions
    • Mctighe S.M., Mar A.C., Romberg C., Bussey T.J., Saksida L.M. A new touchscreen test of pattern separation: effect of hippocampal lesions. NeuroReport 2009, 20:881-885.
    • (2009) NeuroReport , vol.20 , pp. 881-885
    • Mctighe, S.M.1    Mar, A.C.2    Romberg, C.3    Bussey, T.J.4    Saksida, L.M.5
  • 35
    • 0022650213 scopus 로고
    • Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5
    • Morris R.G., Anderson E., Lynch G.S., Baudry M. Selective impairment of learning and blockade of long-term potentiation by an N-methyl-D-aspartate receptor antagonist, AP5. Nature 1986, 319:774-776.
    • (1986) Nature , vol.319 , pp. 774-776
    • Morris, R.G.1    Anderson, E.2    Lynch, G.S.3    Baudry, M.4
  • 36
    • 34547672824 scopus 로고    scopus 로고
    • Visual perception and memory: a new view of medial temporal lobe function in primates and rodents
    • Murray E.A., Bussey T.J., Saksida L.M. Visual perception and memory: a new view of medial temporal lobe function in primates and rodents. Annu. Rev. Neurosci. 2007, 30:99-122.
    • (2007) Annu. Rev. Neurosci. , vol.30 , pp. 99-122
    • Murray, E.A.1    Bussey, T.J.2    Saksida, L.M.3
  • 39
    • 70350741207 scopus 로고    scopus 로고
    • Chronic infusion of PCP via osmotic mini-pumps: a new rodent model of cognitive deficit in schizophrenia characterized by impaired attentional set-shifting (ID/ED) performance
    • Pedersen C.S., Goetghebeur P., Dias R. Chronic infusion of PCP via osmotic mini-pumps: a new rodent model of cognitive deficit in schizophrenia characterized by impaired attentional set-shifting (ID/ED) performance. J. Neurosci. Methods 2009, 185:66-69.
    • (2009) J. Neurosci. Methods , vol.185 , pp. 66-69
    • Pedersen, C.S.1    Goetghebeur, P.2    Dias, R.3
  • 40
    • 38449104511 scopus 로고    scopus 로고
    • Differential regulation of fronto-executive function by the monoamines and acetylcholine
    • Robbins T.W., Roberts A.C. Differential regulation of fronto-executive function by the monoamines and acetylcholine. Cereb. Cortex 2007, 17(Suppl 1):i151-i160.
    • (2007) Cereb. Cortex , vol.17 , pp. i151-i160
    • Robbins, T.W.1    Roberts, A.C.2
  • 41
    • 16244376475 scopus 로고    scopus 로고
    • PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats
    • Rodefer J.S., Murphy E.R., Baxter M.G. PDE10A inhibition reverses subchronic PCP-induced deficits in attentional set-shifting in rats. Eur. J. Neurosci. 2005, 21:1070-1076.
    • (2005) Eur. J. Neurosci. , vol.21 , pp. 1070-1076
    • Rodefer, J.S.1    Murphy, E.R.2    Baxter, M.G.3
  • 42
    • 51749091526 scopus 로고    scopus 로고
    • Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics
    • Rodefer J.S., Nguyen T.N., Karlsson J.J., Arnt J. Reversal of subchronic PCP-induced deficits in attentional set shifting in rats by sertindole and a 5-HT6 receptor antagonist: comparison among antipsychotics. Neuropsychopharmacology 2008, 33:2657-2666.
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2657-2666
    • Rodefer, J.S.1    Nguyen, T.N.2    Karlsson, J.J.3    Arnt, J.4
  • 43
    • 82955236070 scopus 로고    scopus 로고
    • A comparison of the effects of ketamine and phencyclidine with other antagonists of the NMDA receptor in rodent assays of attention and working memory
    • Smith J.W., Gastambide F., Gilmour G., Dix S., Foss J., Lloyd K., Malik N., Tricklebank M. A comparison of the effects of ketamine and phencyclidine with other antagonists of the NMDA receptor in rodent assays of attention and working memory. Psychopharmacology (Berl) 2011, 217:255-269.
    • (2011) Psychopharmacology (Berl) , vol.217 , pp. 255-269
    • Smith, J.W.1    Gastambide, F.2    Gilmour, G.3    Dix, S.4    Foss, J.5    Lloyd, K.6    Malik, N.7    Tricklebank, M.8
  • 45
    • 84862690772 scopus 로고    scopus 로고
    • The pharmacological sensitivity of a touchscreen-based visual discrimination task in the rat using simple and perceptually challenging stimuli
    • Talpos J.C., Fletcher A.C., Circelli C., Tricklebank M.D., Dix S.L. The pharmacological sensitivity of a touchscreen-based visual discrimination task in the rat using simple and perceptually challenging stimuli. Psychopharmacology (Berl) 2012, 221:437-449.
    • (2012) Psychopharmacology (Berl) , vol.221 , pp. 437-449
    • Talpos, J.C.1    Fletcher, A.C.2    Circelli, C.3    Tricklebank, M.D.4    Dix, S.L.5
  • 46
    • 84898635969 scopus 로고    scopus 로고
    • A touch-screen based paired-associates learning (PAL) task for the rat may provide a translatable pharmacological model of human cognitive impairment
    • Talpos J.C., Aerts N., Fellini L., Steckler T. A touch-screen based paired-associates learning (PAL) task for the rat may provide a translatable pharmacological model of human cognitive impairment. Pharmacol. Biochem. Behav. 2014, 122C:97-106.
    • (2014) Pharmacol. Biochem. Behav. , vol.122 C , pp. 97-106
    • Talpos, J.C.1    Aerts, N.2    Fellini, L.3    Steckler, T.4
  • 47
    • 76949106940 scopus 로고    scopus 로고
    • Muscimol, AP5, or scopolamine infused into perirhinal cortex impairs two-choice visual discrimination learning in rats
    • Winters B.D., Bartko S.J., Saksida L.M., Bussey T.J. Muscimol, AP5, or scopolamine infused into perirhinal cortex impairs two-choice visual discrimination learning in rats. Neurobiol. Learn. Mem. 2010, 93:221-228.
    • (2010) Neurobiol. Learn. Mem. , vol.93 , pp. 221-228
    • Winters, B.D.1    Bartko, S.J.2    Saksida, L.M.3    Bussey, T.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.