Distinct patterns of behavioural impairments resulting from fornix transection or neurotoxic lesions of the perirhinal and postrhinal cortices in the rat

Behavioural Brain Research

Volumn 111, Issue 1-2, 2000, Pages 187-202

  Bussey, Timothy J ^a   Duck, Janette ^a   Muir, Janice L ^a   Aggleton, John P ^a  

^a CARDIFF UNIVERSITY   (United Kingdom)

Author keywords

Episodic memory; Object recognition; Spatial memory; Temporal lobe; Visual discrimination

Indexed keywords

ANIMAL EXPERIMENT; ARTICLE; BEHAVIOR DISORDER; BRAIN FORNIX; BRAIN INJURY; CONTROLLED STUDY; HIPPOCAMPUS; INFORMATION PROCESSING; MALE; MAZE TEST; NONHUMAN; PRIORITY JOURNAL; RAT; RECOGNITION; SPATIAL MEMORY; TEMPORAL CORTEX; VISUAL INFORMATION;

ANIMALS; BRAIN MAPPING; DISCRIMINATION LEARNING; FORNIX (BRAIN); HIPPOCAMPUS; MALE; MAZE LEARNING; MENTAL RECALL; MOTOR ACTIVITY; OLFACTORY PATHWAYS; ORIENTATION; PATTERN RECOGNITION, VISUAL; RATS; RATS, INBRED STRAINS; RETENTION (PSYCHOLOGY); TEMPORAL LOBE;

EID: 0034660584     PISSN: 01664328     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-4328(00)00155-8     Document Type: Article

References (45)

1. Aggleton J.P., Brown M.W. Episodic memory, amnesia, and the hippocampal-anterior thalamic axis. Brain Behav. Sci. 22:1999;425-489.
2. Aggleton J.P., Hunt P.R., Rawlins J.N.P. The effects of hippocampal lesions upon spatial and non-spatial tests of working memory. Behav. Brain Res. 19:1986;133-146.
3. Aggleton J.P., Keen S., Warburton E.C., Bussey T.J. Extensive cytotoxic lesions involving both the rhinal cortices and area TE impair recognition but spare spatial alternation in the rat. Brain Res. Bull. 43:1997;279-287.
4. Barnes C.A. Spatial learning and memory processes: the search for their neurobiological mechanisms in the rat. Trends Neurosci. 11:1988;163-169.
5. Buckley M.J., Gaffan D. Perirhinal cortex ablation impairs visual object identification. J. Neurosci. 18:1998;2268-2275.
6. Burwell R.D., Witter M.P., Amaral D.G. Perirhinal and postrhinal cortices of the rat: a review of the neuroanatomical literature and comparison with findings from the monkey brain. Hippocampus. 5:1995;390-408.
7. Bussey T.J., Everitt B.J., Robbins T.W. Dissociable effects of cingulate and medial frontal cortex lesions on stimulus-reward learning using a novel Pavlovian autoshaping procedure for the rat: implications for the neurobiology of emotion. Behav. Neurosci. 111:1997;908-919.
8. Bussey T.J., Muir J.L., Aggleton J.P. Functionally dissociating aspects of event memory: the effects of combined perirhinal and postrhinal cortex lesions on object and place memory in the rat. J. Neurosci. 19:1999;495-502.
9. Bussey T.J., Muir J.L., Everitt B.J., Robbins T.W. Dissociable effects of anterior and posterior cingulate cortex lesions on the acquisition of a conditional visual discrimination: facilitation of early learning vs. impairment of late learning. Behav. Brain Res. 82:1996;45-56.
10. Bussey T.J., Muir J.L., Everitt B.J., Robbins T.W. Triple dissociation of anterior cingulate, posterior cingulate, and medial frontal cortices on visual discrimination tasks using a touchscreen testing procedure for the rat. Behav. Neurosci. 111:1997;920-936.
11. Bussey T.J., Muir J.L., Robbins T.W. A novel automated touchscreen procedure for assessing learning in the rat using computer graphic stimuli. Neurosci. Res. Commun. 15:1994;103-110.
12. Bussey T.J., Warburton E.C., Aggleton J.P., Muir J.L. Fornix lesions can facilitate acquisition of the transverse patterning task: a challenge for 'configural' theories of hippocampal function. J. Neurosci. 18:1998;1622-1631.
13. Dix S.L., Aggleton J.P. Extending the spontaneous preference test of recognition: evidence of object-location and object-context recognition. Behav. Brain Res. 99:1999;191-200.
14. Eichenbaum H., Otto T., Cohen N.J. Two functional components of the hippocampal memory system. Behav. Brain Sci. 17:1994;449-518.
15. Ennaceur A., Aggleton J.P. The effects of neurotoxic lesions of the perirhinal cortex combined to fornix transection on object recognition memory in the rat. Behav. Brain Res. 88:1997;181-193.
16. Ennaceur A., Delacour J. A new one-trial test for neurobiological studies of memory in rats. 1: behavioral data. Behav. Brain Res. 31:1988;49-57.
17. Ennaceur A., Neave N., Aggleton J.P. Neurotoxic lesions of the perirhinal cortex do not mimic the behavioural effects of fornix transection in the rat. Behav. Brain Res. 80:1996;9-25.
18. Ennaceur A., Neave N., Aggleton J.P. Spontaneous object recognition and object location memory in rats: the effects of lesions in the cingulate cortices, the medial prefrontal cortex, the cingulum bundle and the fornix. Exp. Brain Res. 113:1997;509-513.
19. Gaffan D. Dissociated effects of perirhinal cortex ablation, fornix transection and amygdalectomy: evidence for multiple memory systems in the primate temporal lobe. Exp. Brain Res. 99:1994;411-422.
20. Gaffan D. Idiothetic input into object-place configuration as the contribution to memory of the monkey and human hippocampus: a review. Exp. Brain Res. 123:1998;201-209.
21. Gaffan D., Harrison S. Inferotemporal-frontal disconnection and fornix transection in visuomotor conditional learning by monkeys. Behav. Brain Res. 31:1988;149-163.
22. Gaffan D., Parker A. Interaction of perirhinal cortex with the fornix-fimbria: memory for objects and 'object-in-place' memory. J. Neurosci. 16:1996;5864-5869.
23. Glenn M.J., Mumby D.G. Place memory is intact in rats with perirhinal cortex lesions. Behav. Neurosci. 112:1999;1353-1365.
24. Gray J.A., McNaughton N. Comparison between the behavioural effects of septal and hippocampal lesions: a review. Neurosci. Biobehav. Rev. 7:1983;119-188.
25. Jay T.M., Witter M.P. Distribution of hippocampal CA1 and subicular efferents in the prefrontal cortex of the rat studied by means of anterograde transport of Phaseolus vulgaris-leucoagglutin. J. Comp. Neurol. 313:1991;574-586.
26. Kolb B., Buhrmann K., McDonald R., Sutherland R.J. Dissociation of the medial prefrontal, posterior parietal, and posterior temporal cortex for spatial navigation and recognition memory in the rat. Cereb. Cortex. 4:1994;664-680.
27. Liu P., Bilkey D.K. Excitotoxic lesions centered on perirhinal cortex produce delay-dependent deficits in a test of spatial memory. Behav. Neurosci. 112:1998;512-524.
28. Liu P., Bilkey D.K. Lesions of perirhinal cortex produce spatial memory deficits in the radial maze. Hippocampus. 8:1998;114-121.
29. Liu P., Bilkey D.K. Perirhinal cortex contributions to performance in the Morris water maze. Behav. Neurosci. 112:1998;304-315.
30. Morris R.G.M., Garrud P., Rawlins J.N.P., O'Keefe J. Place navigation impaired in rats with hippocampal lesions. Nature. 297:1982;681-683.
31. Mumby D.G., Pinel J.P.J. Rhinal cortex lesions and object recognition in rats. Behav. Neurosci. 108:1994;11-18.
32. Murray E.A., Bussey T.J. Perceptual-mnemonic functions of perirhinal cortex. Trends Cogn. Sci. 3:1999;142-151.
33. Murray E.A., Gaffan D., Mishkin M. Neural substrates of visual stimulus-stimulus association in rhesus monkeys. J. Neurosci. 13:1993;4549-4561.
34. Murray E.A., Wise S.P. Role of the hippocampus plus subjacent cortex but not amygdala in visuomotor conditional learning in rhesus monkeys. Behav. Neurosci. 110:1996;1261-1270.
35. Paxinos G., Watson C. The rat brain in stereotaxic coordinates. 1997;Academic Press, New York.
36. Rupniak N.M.J., Gaffan D. Monkey hippocampus and learning about spatially directed movements. J. Neurosci. 7:1987;2331-2337.
37. Squire L.R., Zola-Morgan S. The medial temporal lobe memory system. Science. 253:1991;1380-1386.
38. Suzuki W.A. The anatomy, physiology and functions of the perirhinal cortex. Curr. Opin. Neurobiol. 6:1996;179-186.
39. Swanson L.W., Kohler C., Bjorklund A. The limbic region. I: The septohippocampal system. Bjorklund A., Hokfelt T., Swanson L.W. Handbook of Chemical Neuroanatomy: Integrated Systems of the CNS, Part 1. 1987;127-277 Elsevier Science.
40. Sziklas V., Lebel S., Petrides M. Conditional associative learning and the hippocampal system. Hippocampus. 8:1998;131-137.
41. Whishaw I.Q., Gorny B. Path integration absent in scent-tracking fimbria-fornix rats: evidence for hippocampal involvement in 'sense of direction' and 'sense of distance' using self-movement cues. J. Neurosci. 19:1999;4662-4673.
42. Wiig K.A., Bilkey D.K. The effects of perirhinal cortical lesions on spatial reference memory in the rat. Behav. Brain Res. 63:1994;101-109.
43. Wiig K.A., Burwell R.D. Memory impairment on a delayed non-matching-to-position task after lesions of the perirhinal cortex in rats. Behav. Neurosci. 112:1998;827-838.
44. Wise S.P., Murray E.A. Role of the hippocampal system in conditional motor learning: mapping antecedents to action. Hippocampus. 9:1999;101-117.
45. Witter M., Groenewegen H., Silva F.L.d, Lohman A. Functional organization of the extrinsic and intrinsic circuitry of the parahippocampal region. Prog. Neurobiol. 33:1989;161-253.