Role of mitogen-activated protein kinase phosphatase-1 in corticosteroid insensitivity of chronic oxidant lung injury

European Journal of Pharmacology

Volumn 744, Issue , 2014, Pages 108-114

  Pinart, Mariona ^a   Hussain, Farhana ^a   Shirali, Sima ^a   Li, Feng ^a   Zhu, Jie ^a   Clark, Andrew R ^b   Ammit, Alaina J ^c   Chung, Kian Fan ^a  

^a NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

^c UNIVERSITY OF SYDNEY   (Australia)

Author keywords

Bronchial hyperresponsiveness; Emphysema; Lung inflammation; Mitogen activated protein kinase; Ozone exposure; phosphatase 1 (MKP 1)

Indexed keywords

COLLAGEN; CORTICOSTEROID; DEXAMETHASONE; INTERLEUKIN 13; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; DUSP1 PROTEIN, MOUSE; MACROPHAGE ELASTASE; OXIDIZING AGENT; OZONE;

ANIMAL EXPERIMENT; ARTICLE; BRONCHUS HYPERREACTIVITY; CHRONIC OBSTRUCTIVE LUNG DISEASE; CHRONIC OXIDANT LUNG INJURY; CONTROLLED STUDY; DRUG MECHANISM; EMPHYSEMA; LONG TERM EXPOSURE; LOW DRUG DOSE; LUNG INJURY; MALE; MOUSE; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; PNEUMONIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WILD TYPE; ANIMAL; BRONCHIAL HYPERREACTIVITY; C57BL MOUSE; DRUG EFFECTS; INFLAMMATION; METABOLISM; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA;

ADRENAL CORTEX HORMONES; ANIMALS; BRONCHIAL HYPERREACTIVITY; DEXAMETHASONE; DUAL SPECIFICITY PHOSPHATASE 1; INFLAMMATION; INTERLEUKIN-13; LUNG INJURY; MALE; MATRIX METALLOPROTEINASE 12; MICE; MICE, INBRED C57BL; OXIDANTS; OXIDATIVE STRESS; OZONE; PULMONARY DISEASE, CHRONIC OBSTRUCTIVE; PULMONARY EMPHYSEMA;

EID: 84918783953     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2014.10.003     Document Type: Article

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