메뉴 건너뛰기




Volumn 37, Issue 4, 2011, Pages 933-942

Inhibition of p38 MAPK-dependent bronchial contraction after ozone by corticosteroids

Author keywords

Acetylcholine; Airway smooth muscle; Dexamethasone; Heat shock protein 27; Mitogen activated protein kinase phosphatase 1; p38 mitogen activated protein kinase

Indexed keywords

4 [4 (4 FLUOROPHENYL) 5 (2 METHOXY 4 PYRIMIDINYL) 1 IMIDAZOLYL]CYCLOHEXANOL; ACETYLCHOLINE; DEXAMETHASONE; HEAT SHOCK PROTEIN 27; MITOGEN ACTIVATED PROTEIN KINASE P38; MITOGEN ACTIVATED PROTEIN KINASE PHOSPHATASE 1; OZONE;

EID: 79953695109     PISSN: 09031936     EISSN: 13993003     Source Type: Journal    
DOI: 10.1183/09031936.00021110     Document Type: Article
Times cited : (33)

References (37)
  • 1
    • 0142026209 scopus 로고    scopus 로고
    • P38 MAP kinases: Key signalling molecules as therapeutic targets for inflammatory diseases
    • Kumar S, Boehm J, Lee JC. p38 MAP kinases: key signalling molecules as therapeutic targets for inflammatory diseases. Nat Rev Drug Discov 2003; 2: 717-726. (Pubitemid 37361787)
    • (2003) Nature Reviews Drug Discovery , vol.2 , Issue.9 , pp. 717-726
    • Kumar, S.1    Boehm, J.2    Lee, J.C.3
  • 2
    • 33644768012 scopus 로고    scopus 로고
    • Kinase inhibitors and airway inflammation
    • DOI 10.1016/j.ejphar.2005.12.054, PII S001429990501383X, The Pharmacology of the Respiratory Tract
    • Adcock IM, Chung KF, Caramori G, et al. Kinase inhibitors and airway inflammation. Eur J Pharmacol 2006; 533: 118-132. (Pubitemid 43340009)
    • (2006) European Journal of Pharmacology , vol.533 , Issue.1-3 , pp. 118-132
    • Adcock, I.M.1    Chung, K.F.2    Caramori, G.3    Ito, K.4
  • 6
    • 17744377218 scopus 로고    scopus 로고
    • Signal-transduction pathways that regulate visceral smooth muscle function III. Coupling of muscarinic receptors to signaling kinases and effector proteins in gastrointestinal smooth muscles
    • DOI 10.1152/ajpgi.00530.2004
    • Gerthoffer WT. Signal-transduction pathways that regulate visceral smooth muscle function. III. Coupling of muscarinic receptors to signaling kinases and effector proteins in gastrointestinal smooth muscles. Am J Physiol Gastrointest Liver Physiol 2005; 288: G849-G853. (Pubitemid 40575726)
    • (2005) American Journal of Physiology - Gastrointestinal and Liver Physiology , vol.288 , Issue.5
    • Gerthoffer, W.T.1
  • 8
    • 55949102910 scopus 로고    scopus 로고
    • Role of p38 mitogenactivated protein kinase in ozone-induced airway hyperresponsiveness and inflammation
    • Williams AS, Issa R, Durham A, et al. Role of p38 mitogenactivated protein kinase in ozone-induced airway hyperresponsiveness and inflammation. Eur J Pharmacol 2008; 600: 117-122.
    • (2008) Eur J Pharmacol , vol.600 , pp. 117-122
    • Williams, A.S.1    Issa, R.2    Durham, A.3
  • 12
    • 0028955653 scopus 로고
    • Potentiation by tumour necrosis factor-a of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells
    • Amrani Y, Martinet N, Bronner C. Potentiation by tumour necrosis factor-a of calcium signals induced by bradykinin and carbachol in human tracheal smooth muscle cells. Br J Pharmacol 1995; 114: 4-5.
    • (1995) Br J Pharmacol , vol.114 , pp. 4-5
    • Amrani, Y.1    Martinet, N.2    Bronner, C.3
  • 15
    • 34248679869 scopus 로고    scopus 로고
    • Dual-specificity phosphatase 1: A critical regulator of innate immune responses
    • DOI 10.1042/BST0341018
    • Abraham SM, Clark AR. Dual-specificity phosphatase 1: a critical regulator of innate immune responses. Biochem Soc Trans 2006; 34: 1018-1023. (Pubitemid 46768980)
    • (2006) Biochemical Society Transactions , vol.34 , Issue.6 , pp. 1018-1023
    • Abraham, S.M.1    Clark, A.R.2
  • 16
    • 34249805700 scopus 로고    scopus 로고
    • Corticosteroid inhibition of growth-related oncogene protein-α via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells
    • Issa R, Xie S, Khorasani N, et al. Corticosteroid inhibition of growth-related oncogene protein-α via mitogen-activated kinase phosphatase-1 in airway smooth muscle cells. J Immunol 2007; 178: 7366-7375. (Pubitemid 46847464)
    • (2007) Journal of Immunology , vol.178 , Issue.11 , pp. 7366-7375
    • Issa, R.1    Xie, S.2    Khorasani, N.3    Sukkar, M.4    Adcock, I.M.5    Lee, K.-Y.6    Kian, F.C.7
  • 17
    • 0036841288 scopus 로고    scopus 로고
    • Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
    • DOI 10.1128/MCB.22.22.7802-7811.2002
    • Lasa M, Abraham SM, Boucheron C, et al. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol Cell Biol 2002; 22: 7802-7811. (Pubitemid 35217291)
    • (2002) Molecular and Cellular Biology , vol.22 , Issue.22 , pp. 7802-7811
    • Lasa, M.1    Abraham, S.M.2    Boucheron, C.3    Saklatvala, J.4    Clark, A.R.5
  • 18
    • 48649103130 scopus 로고    scopus 로고
    • Corticosteroids reduce IL-6 in ASM cells via up-regulation of MKP-1
    • Quante T, Ng YC, Ramsay EE, et al. Corticosteroids reduce IL-6 in ASM cells via up-regulation of MKP-1. Am J Respir Cell Mol Biol 2008; 39: 208-217.
    • (2008) Am J Respir Cell Mol Biol , vol.39 , pp. 208-217
    • Quante, T.1    Ng, Y.C.2    Ramsay, E.E.3
  • 19
    • 0029757347 scopus 로고    scopus 로고
    • Disruption of the erp/mkp-1 gene does not affect mouse development: Normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts
    • Dorfman K, Carrasco D, Gruda M, et al. Disruption of the erp/mkp-1 gene does not affect mouse development: normal MAP kinase activity in ERP/MKP-1-deficient fibroblasts. Oncogene 1996; 13: 925-931. (Pubitemid 26329078)
    • (1996) Oncogene , vol.13 , Issue.5 , pp. 925-931
    • Dorfman, K.1    Carrasco, D.2    Gruda, M.3    Ryan, C.4    Lira, S.A.5    Bravo, R.6
  • 22
    • 77952334511 scopus 로고    scopus 로고
    • A benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor alpha production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation
    • Mourey RJ, Burnette BL, Brustkern SJ, et al. A benzothiophene inhibitor of mitogen-activated protein kinase-activated protein kinase 2 inhibits tumor necrosis factor alpha production and has oral anti-inflammatory efficacy in acute and chronic models of inflammation. J Pharmacol Exp Ther 2010; 333: 797-807.
    • (2010) J Pharmacol Exp Ther , vol.333 , pp. 797-807
    • Mourey, R.J.1    Burnette, B.L.2    Brustkern, S.J.3
  • 23
    • 0031057892 scopus 로고    scopus 로고
    • Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells
    • Huot J, Houle F, Marceau F, et al. Oxidative stress-induced actin reorganization mediated by the p38 mitogen-activated protein kinase/heat shock protein 27 pathway in vascular endothelial cells. Circ Res 1997; 80: 383-392. (Pubitemid 27093353)
    • (1997) Circulation Research , vol.80 , Issue.3 , pp. 383-392
    • Huot, J.1    Houle, F.2    Marceau, F.3    Landry, J.4
  • 24
    • 0030669445 scopus 로고    scopus 로고
    • Phosphorylation of the 27-kDa heat shock protein via p38 MAP kinase and MAPKAP kinase in smooth muscle
    • Larsen JK, Yamboliev IA, Weber LA, et al. Phosphorylation of the 27-kDa heat shock protein via p38 MAP kinase and MAPKAP kinase in smooth muscle. Am J Physiol 1997; 273: L930-L940.
    • (1997) Am J Physiol , vol.273
    • Larsen, J.K.1    Yamboliev, I.A.2    Weber, L.A.3
  • 27
    • 0141680396 scopus 로고    scopus 로고
    • MAPK regulation of gene expression in airway smooth muscle
    • DOI 10.1016/S1569-9048(03)00150-2
    • Gerthoffer WT, Singer CA. MAPK regulation of gene expression in airway smooth muscle. Respir Physiol Neurobiol 2003; 137: 237-250. (Pubitemid 37153285)
    • (2003) Respiratory Physiology and Neurobiology , vol.137 , Issue.2-3 , pp. 237-250
    • Gerthoffer, W.T.1    Singer, C.A.2
  • 28
    • 35348907987 scopus 로고    scopus 로고
    • Protein kinases as small molecule inhibitor targets in inflammation
    • DOI 10.2174/092986707781696636
    • Gaestel M, Mengel A, Bothe U, et al. Protein kinases as small molecule inhibitor targets in inflammation. Curr Med Chem 2007; 14: 2214-2234. (Pubitemid 47570683)
    • (2007) Current Medicinal Chemistry , vol.14 , Issue.21 , pp. 2214-2234
    • Gaestel, M.1    Mengel, A.2    Bothe, U.3    Asadullah, K.4
  • 29
    • 18344399012 scopus 로고    scopus 로고
    • Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells
    • DOI 10.1074/jbc.275.15.11418
    • Galan A, Garcia-Bermejo ML, Troyano A, et al. Stimulation of p38 mitogen-activated protein kinase is an early regulatory event for the cadmium-induced apoptosis in human promonocytic cells. J Biol Chem 2000; 275: 11418-11424. (Pubitemid 30212795)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.15 , pp. 11418-11424
    • Galan, A.1    Garcia-Bermejo, M.L.2    Troyano, A.3    Vilaboa, N.E.4    De Blas, E.5    Kazanietz, M.G.6    Aller, P.7
  • 30
    • 0034670047 scopus 로고    scopus 로고
    • Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages
    • Matsuguchi T, Musikacharoen T, Ogawa T, et al. Gene expressions of Toll-like receptor 2, but not Toll-like receptor 4, is induced by LPS and inflammatory cytokines in mouse macrophages. J Immunol 2000; 165: 5767-5772.
    • (2000) J Immunol , vol.165 , pp. 5767-5772
    • Matsuguchi, T.1    Musikacharoen, T.2    Ogawa, T.3
  • 31
    • 0037083375 scopus 로고    scopus 로고
    • MAPKK-independent activation of p38α mediated by TAB1-dependent autophosphorylation of p38α
    • DOI 10.1126/science.1067289
    • Ge B, Gram H, Di Padova F, et al. MAPKK-independent activation of p38alpha mediated by TAB1-dependent autophosphorylation of p38α. Science 2002; 295: 1291-1294. (Pubitemid 34157620)
    • (2002) Science , vol.295 , Issue.5558 , pp. 1291-1294
    • Ge, B.1    Gram, H.2    Di, P.F.3    Huang, B.4    New, L.5    Ulevitch, R.J.6    Luo, Y.7    Han, J.8
  • 33
    • 0032578559 scopus 로고    scopus 로고
    • The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding
    • DOI 10.1021/bi980832y
    • Frantz B, Klatt T, Pang M, et al. The activation state of p38 mitogen-activated protein kinase determines the efficiency of ATP competition for pyridinylimidazole inhibitor binding. Biochemistry 1998; 37: 13846-13853. (Pubitemid 28455562)
    • (1998) Biochemistry , vol.37 , Issue.39 , pp. 13846-13853
    • Frantz, B.1    Klatt, T.2    Pang, M.3    Parsons, J.4    Rolando, A.5    Williams, H.6    Tocci, M.J.7    O'Keefe, S.J.8    O'Neill, E.A.9
  • 34
    • 0029658978 scopus 로고    scopus 로고
    • 1 receptor coupling by dexamethasone in human cultured airway smooth muscle
    • Hardy E, Farahani M, Hall IP. Regulation of histamine H1 receptor coupling by dexamethasone in human cultured airway smooth muscle. Br J Pharmacol 1996; 118: 1079-1084. (Pubitemid 26261285)
    • (1996) British Journal of Pharmacology , vol.118 , Issue.4 , pp. 1079-1084
    • Hardy, E.1    Farahani, M.2    Hall, I.P.3
  • 35
    • 0025977315 scopus 로고
    • Effect of steroid hormones on muscarinic receptors of bronchial smooth muscle
    • Nabishah BM, Morat PB, Kadir BA, et al. Effect of steroid hormones on muscarinic receptors of bronchial smooth muscle. Gen Pharmacol 1991; 22: 389-392.
    • (1991) Gen Pharmacol , vol.22 , pp. 389-392
    • Nabishah, B.M.1    Morat, P.B.2    Kadir, B.A.3
  • 36
    • 0036191962 scopus 로고    scopus 로고
    • Glucocorticoids reverse IL-1β-induced impairment of β-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases
    • Mak JC, Hisada T, Salmon M, et al. Glucocorticoids reverse IL-1β-induced impairment of β-adrenoceptor-mediated relaxation and up-regulation of G-protein-coupled receptor kinases. Br J Pharmacol 2002; 135: 987-996. (Pubitemid 34214458)
    • (2002) British Journal of Pharmacology , vol.135 , Issue.4 , pp. 987-996
    • Mak, J.C.W.1    Hisada, T.2    Salmon, M.3    Barnes, P.J.4    Chung, K.F.5
  • 37
    • 58849117106 scopus 로고    scopus 로고
    • Steroids augment relengthening of contracted airway smooth muscle: Potential additional mechanism of benefit in asthma
    • Lakser OJ, Dowell ML, Hoyte FL, et al. Steroids augment relengthening of contracted airway smooth muscle: potential additional mechanism of benefit in asthma. Eur Respir J 2008; 32: 1224-1230.
    • (2008) Eur Respir J , vol.32 , pp. 1224-1230
    • Lakser, O.J.1    Dowell, M.L.2    Hoyte, F.L.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.