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Volumn 19, Issue , 2015, Pages 43-52

Aging and dyslipidemia: A review of potential mechanisms

Author keywords

Aging; Cardiovascular disease; Dyslipidemia; Lipoprotein metabolism

Indexed keywords

ANDROGEN; CHOLESTEROL; CLOFIBRATE; FATTY ACID; FENOFIBRATE; GEMFIBROZIL; GROWTH HORMONE; GROWTH HORMONE RELEASING FACTOR; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LIPOFUSCIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; TESTOSTERONE; TRIACYLGLYCEROL; LIPID;

EID: 84918778306     PISSN: 15681637     EISSN: 18729649     Source Type: Journal    
DOI: 10.1016/j.arr.2014.12.001     Document Type: Review
Times cited : (198)

References (136)
  • 1
    • 0020522367 scopus 로고
    • Joint distribution of lipoprotein cholesterol classes: The Framingham Study
    • Abbott R.D., Garrison R.J., Wilson P.W., et al. Joint distribution of lipoprotein cholesterol classes: The Framingham Study. Arterioscler. Thromb. Vasc. Biol. 1983, 3:260-272.
    • (1983) Arterioscler. Thromb. Vasc. Biol. , vol.3 , pp. 260-272
    • Abbott, R.D.1    Garrison, R.J.2    Wilson, P.W.3
  • 2
    • 0035914298 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines
    • Akiyama T.E., Nicol C.J., Fievet C., Staels B., Ward J.M., Auwerx J., Lee S.S., Gonzalez F.J., Peters J.M. Peroxisome proliferator-activated receptor-alpha regulates lipid homeostasis, but is not associated with obesity: studies with congenic mouse lines. J. Biol. Chem. 2001, 276:39088-39093.
    • (2001) J. Biol. Chem. , vol.276 , pp. 39088-39093
    • Akiyama, T.E.1    Nicol, C.J.2    Fievet, C.3    Staels, B.4    Ward, J.M.5    Auwerx, J.6    Lee, S.S.7    Gonzalez, F.J.8    Peters, J.M.9
  • 3
    • 0030598949 scopus 로고    scopus 로고
    • The relationship of natural androgens to coronary heart disease in males: a review
    • Alexandersen P., Haarbo J., Christiansen C. The relationship of natural androgens to coronary heart disease in males: a review. Atherosclerosis 1996, 125:1-13.
    • (1996) Atherosclerosis , vol.125 , pp. 1-13
    • Alexandersen, P.1    Haarbo, J.2    Christiansen, C.3
  • 4
    • 0028264279 scopus 로고
    • Growth hormone and hepatic lipoprotein metabolism
    • Angelin B., Rudling M. Growth hormone and hepatic lipoprotein metabolism. Curr. Opin. Lipidol. 1994, 5:160-165.
    • (1994) Curr. Opin. Lipidol. , vol.5 , pp. 160-165
    • Angelin, B.1    Rudling, M.2
  • 5
    • 0037031061 scopus 로고    scopus 로고
    • MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial
    • Anonymous
    • Anonymous MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20,536 high-risk individuals: a randomised placebo-controlled trial. Lancet 2002, 360:7-22.
    • (2002) Lancet , vol.360 , pp. 7-22
  • 6
    • 0036254607 scopus 로고    scopus 로고
    • Insulin resistance in type 2 diabetes: role of fatty acids
    • Arner P. Insulin resistance in type 2 diabetes: role of fatty acids. Diabetes Metab. Res. Rev. 2002, 18(Suppl. 2):S5-S9.
    • (2002) Diabetes Metab. Res. Rev. , vol.18 , pp. S5-S9
    • Arner, P.1
  • 8
    • 78449281377 scopus 로고    scopus 로고
    • Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials
    • Baigent C., Blackwell L., Emberson J., Holland L.E., Reith C., Bhala N., Peto R., Barnes E.H., Keech A., Simes J., Collins R. Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials. Lancet 2010, 376:1670-1681.
    • (2010) Lancet , vol.376 , pp. 1670-1681
    • Baigent, C.1    Blackwell, L.2    Emberson, J.3    Holland, L.E.4    Reith, C.5    Bhala, N.6    Peto, R.7    Barnes, E.H.8    Keech, A.9    Simes, J.10    Collins, R.11
  • 9
    • 0014452681 scopus 로고
    • The effect of repeated stimulation of the pancreas on the pancreatic secretion in young and aged men
    • Bartos V., Groh J. The effect of repeated stimulation of the pancreas on the pancreatic secretion in young and aged men. Gerontol. Clin. (Basel) 1969, 11:56-62.
    • (1969) Gerontol. Clin. (Basel) , vol.11 , pp. 56-62
    • Bartos, V.1    Groh, J.2
  • 10
    • 0029842574 scopus 로고    scopus 로고
    • Age-related changes in body composition are associated with hepatic insulin resistance in conscious rats
    • Barzilai N., Rossetti L. Age-related changes in body composition are associated with hepatic insulin resistance in conscious rats. Am. J. Physiol. 1996, 270:E930-E936.
    • (1996) Am. J. Physiol. , vol.270 , pp. E930-E936
    • Barzilai, N.1    Rossetti, L.2
  • 11
    • 0036183630 scopus 로고    scopus 로고
    • The mechanisms of action of PPARs
    • Berger J., Moller D.E. The mechanisms of action of PPARs. Annu. Rev. Med. 2002, 53:409-435.
    • (2002) Annu. Rev. Med. , vol.53 , pp. 409-435
    • Berger, J.1    Moller, D.E.2
  • 12
    • 0027062816 scopus 로고
    • Abdominal fat distribution and the metabolic syndrome
    • Bjorntorp P. Abdominal fat distribution and the metabolic syndrome. J. Cardiovasc. Pharmacol. 1992, 20(Suppl. 8):S26-S28.
    • (1992) J. Cardiovasc. Pharmacol. , vol.20 , pp. S26-S28
    • Bjorntorp, P.1
  • 13
    • 0028342686 scopus 로고
    • Mechanisms of fatty acid-induced inhibition of glucose uptake
    • Boden G., Chen X., Ruiz J., White J.V., Rossetti L. Mechanisms of fatty acid-induced inhibition of glucose uptake. J. Clin. Invest. 1994, 93:2438-2446.
    • (1994) J. Clin. Invest. , vol.93 , pp. 2438-2446
    • Boden, G.1    Chen, X.2    Ruiz, J.3    White, J.V.4    Rossetti, L.5
  • 14
    • 0028209552 scopus 로고
    • Free fatty acid and glucose metabolism in human aging: evidence for operation of the Randle cycle
    • Bonadonna R.C., Groop L.C., Simonson D.C., DeFronzo R.A. Free fatty acid and glucose metabolism in human aging: evidence for operation of the Randle cycle. Am. J. Physiol. 1994, 266:E501-E509.
    • (1994) Am. J. Physiol. , vol.266 , pp. E501-E509
    • Bonadonna, R.C.1    Groop, L.C.2    Simonson, D.C.3    DeFronzo, R.A.4
  • 16
    • 0030047806 scopus 로고    scopus 로고
    • Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat
    • Braissant O., Foufelle F., Scotto C., Dauca M., Wahli W. Differential expression of peroxisome proliferator-activated receptors (PPARs): tissue distribution of PPAR-alpha, -beta, and -gamma in the adult rat. Endocrinology 1996, 137:354-366.
    • (1996) Endocrinology , vol.137 , pp. 354-366
    • Braissant, O.1    Foufelle, F.2    Scotto, C.3    Dauca, M.4    Wahli, W.5
  • 18
  • 19
    • 0023230236 scopus 로고
    • Usefulness of sex steroid hormone levels in predicting coronary artery disease in men
    • Cauley J.A., Gutai J.P., Kuller L.H., Dai W.S. Usefulness of sex steroid hormone levels in predicting coronary artery disease in men. Am. J. Cardiol. 1987, 60:771-777.
    • (1987) Am. J. Cardiol. , vol.60 , pp. 771-777
    • Cauley, J.A.1    Gutai, J.P.2    Kuller, L.H.3    Dai, W.S.4
  • 22
    • 0034609562 scopus 로고    scopus 로고
    • Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies
    • Danesh J., Collins R., Peto R. Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies. Circulation 2000, 102:1082-1085.
    • (2000) Circulation , vol.102 , pp. 1082-1085
    • Danesh, J.1    Collins, R.2    Peto, R.3
  • 23
    • 0033305213 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptors: nuclear control of metabolism
    • Desvergne B., Wahli W. Peroxisome proliferator-activated receptors: nuclear control of metabolism. Endocr. Rev. 1999, 20:649-688.
    • (1999) Endocr. Rev. , vol.20 , pp. 649-688
    • Desvergne, B.1    Wahli, W.2
  • 24
    • 0021811872 scopus 로고
    • Influence of age on secretion of cholesterol and synthesis of bile acids by the liver
    • Einarsson K., Nilsell K., Leijd B., Angelin B. Influence of age on secretion of cholesterol and synthesis of bile acids by the liver. N. Engl. J. Med. 1985, 313:277-282.
    • (1985) N. Engl. J. Med. , vol.313 , pp. 277-282
    • Einarsson, K.1    Nilsell, K.2    Leijd, B.3    Angelin, B.4
  • 26
    • 0026471942 scopus 로고
    • In vivo growth hormone treatment stimulates secretion of very low density lipoprotein by the isolated perfused rat liver
    • Elam M.B., Wilcox H.G., Solomon S.S., Heimberg M. In vivo growth hormone treatment stimulates secretion of very low density lipoprotein by the isolated perfused rat liver. Endocrinology 1992, 131:2717-2722.
    • (1992) Endocrinology , vol.131 , pp. 2717-2722
    • Elam, M.B.1    Wilcox, H.G.2    Solomon, S.S.3    Heimberg, M.4
  • 27
    • 0034108483 scopus 로고    scopus 로고
    • Men with coronary artery disease have lower levels of androgens than men with normal coronary angiograms
    • English K.M., Mandour O., Steeds R.P., Diver M.J., Jones T.H., Channer K.S. Men with coronary artery disease have lower levels of androgens than men with normal coronary angiograms. Eur. Heart J. 2000, 21:890-894.
    • (2000) Eur. Heart J. , vol.21 , pp. 890-894
    • English, K.M.1    Mandour, O.2    Steeds, R.P.3    Diver, M.J.4    Jones, T.H.5    Channer, K.S.6
  • 29
    • 0030689726 scopus 로고    scopus 로고
    • The influence of age on low density lipoprotein metabolism: effects of cholestyramine treatment in young and old healthy male subjects
    • Ericsson S., Berglund L., Frostegard J., Einarsson K., Angelin B. The influence of age on low density lipoprotein metabolism: effects of cholestyramine treatment in young and old healthy male subjects. J. Intern. Med. 1997, 242:329-337.
    • (1997) J. Intern. Med. , vol.242 , pp. 329-337
    • Ericsson, S.1    Berglund, L.2    Frostegard, J.3    Einarsson, K.4    Angelin, B.5
  • 33
    • 0030818676 scopus 로고    scopus 로고
    • Total, LDL, and HDL cholesterol decrease with age in older men and women. The Rancho Bernardo Study 1984-1994
    • Ferrara A., Barrett-Connor E., Shan J. Total, LDL, and HDL cholesterol decrease with age in older men and women. The Rancho Bernardo Study 1984-1994. Circulation 1997, 96:37-43.
    • (1997) Circulation , vol.96 , pp. 37-43
    • Ferrara, A.1    Barrett-Connor, E.2    Shan, J.3
  • 35
    • 84887342376 scopus 로고    scopus 로고
    • Relation between serum free fatty acids and adiposity, insulin resistance, and cardiovascular risk factors from adolescence to adulthood
    • Frohnert B.I., Jacobs D.R., Steinberger J., Moran A., Steffen L.M., Sinaiko A.R. Relation between serum free fatty acids and adiposity, insulin resistance, and cardiovascular risk factors from adolescence to adulthood. Diabetes 2013, 62:3163-3169.
    • (2013) Diabetes , vol.62 , pp. 3163-3169
    • Frohnert, B.I.1    Jacobs, D.R.2    Steinberger, J.3    Moran, A.4    Steffen, L.M.5    Sinaiko, A.R.6
  • 36
    • 34548419618 scopus 로고    scopus 로고
    • Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol
    • Galman C., Matasconi M., Persson L., Parini P., Angelin B., Rudling M. Age-induced hypercholesterolemia in the rat relates to reduced elimination but not increased intestinal absorption of cholesterol. Am. J. Physiol. Endocrinol. Metab. 2007, 293:E737-E742.
    • (2007) Am. J. Physiol. Endocrinol. Metab. , vol.293 , pp. E737-E742
    • Galman, C.1    Matasconi, M.2    Persson, L.3    Parini, P.4    Angelin, B.5    Rudling, M.6
  • 37
    • 3442895916 scopus 로고    scopus 로고
    • Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes
    • Gao Z., Zhang X., Zuberi A., Hwang D., Quon M.J., Lefevre M., Ye J. Inhibition of insulin sensitivity by free fatty acids requires activation of multiple serine kinases in 3T3-L1 adipocytes. Mol. Endocrinol. 2004, 18:2024-2034.
    • (2004) Mol. Endocrinol. , vol.18 , pp. 2024-2034
    • Gao, Z.1    Zhang, X.2    Zuberi, A.3    Hwang, D.4    Quon, M.J.5    Lefevre, M.6    Ye, J.7
  • 39
    • 0033860359 scopus 로고    scopus 로고
    • Insulin resistance and cardiovascular disease
    • Ginsberg H.N. Insulin resistance and cardiovascular disease. J. Clin. Invest. 2000, 106:453-458.
    • (2000) J. Clin. Invest. , vol.106 , pp. 453-458
    • Ginsberg, H.N.1
  • 40
    • 78649367996 scopus 로고    scopus 로고
    • Management of dyslipidemia in the elderly population
    • Gobal F.A., Mehta J.L. Management of dyslipidemia in the elderly population. Ther. Adv. Cardiovasc. Dis. 2010, 4:375-383.
    • (2010) Ther. Adv. Cardiovasc. Dis. , vol.4 , pp. 375-383
    • Gobal, F.A.1    Mehta, J.L.2
  • 41
    • 0025818232 scopus 로고
    • An examination of research design effects on the association of testosterone and male aging: results of a meta-analysis
    • Gray A., Berlin J.A., McKinlay J.B., Longcope C. An examination of research design effects on the association of testosterone and male aging: results of a meta-analysis. J. Clin. Epidemiol. 1991, 44:671-684.
    • (1991) J. Clin. Epidemiol. , vol.44 , pp. 671-684
    • Gray, A.1    Berlin, J.A.2    McKinlay, J.B.3    Longcope, C.4
  • 42
    • 0028033268 scopus 로고
    • The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression
    • Gulick T., Cresci S., Caira T., Moore D.D., Kelly D.P. The peroxisome proliferator-activated receptor regulates mitochondrial fatty acid oxidative enzyme gene expression. Proc. Natl. Acad. Sci. U. S. A. 1994, 91:11012-11016.
    • (1994) Proc. Natl. Acad. Sci. U. S. A. , vol.91 , pp. 11012-11016
    • Gulick, T.1    Cresci, S.2    Caira, T.3    Moore, D.D.4    Kelly, D.P.5
  • 43
    • 0018950079 scopus 로고
    • Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin
    • Harman S.M., Tsitouras P.D. Reproductive hormones in aging men. I. Measurement of sex steroids, basal luteinizing hormone, and Leydig cell response to human chorionic gonadotropin. J. Clin. Endocrinol. Metab. 1980, 51:35-40.
    • (1980) J. Clin. Endocrinol. Metab. , vol.51 , pp. 35-40
    • Harman, S.M.1    Tsitouras, P.D.2
  • 44
    • 0035097033 scopus 로고    scopus 로고
    • Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging
    • Harman S.M., Metter E.J., Tobin J.D., Pearson J., Blackman M.R. Longitudinal effects of aging on serum total and free testosterone levels in healthy men. Baltimore Longitudinal Study of Aging. J. Clin. Endocrinol. Metab. 2001, 86:724-731.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 724-731
    • Harman, S.M.1    Metter, E.J.2    Tobin, J.D.3    Pearson, J.4    Blackman, M.R.5
  • 45
    • 0037840433 scopus 로고    scopus 로고
    • Testosterone administration to men increases hepatic lipase activity and decreases HDL and LDL size in 3 wk
    • Herbst K.L., Amory J.K., Brunzell J.D., Chansky H.A., Bremner W.J. Testosterone administration to men increases hepatic lipase activity and decreases HDL and LDL size in 3 wk. Am. J. Physiol. Endocrinol. Metab. 2003, 284:E1112-E1118.
    • (2003) Am. J. Physiol. Endocrinol. Metab. , vol.284 , pp. E1112-E1118
    • Herbst, K.L.1    Amory, J.K.2    Brunzell, J.D.3    Chansky, H.A.4    Bremner, W.J.5
  • 47
    • 32944468701 scopus 로고    scopus 로고
    • Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat
    • Hilmer S.N., Cogger V.C., Fraser R., McLean A.J., Sullivan D., Le Couteur D.G. Age-related changes in the hepatic sinusoidal endothelium impede lipoprotein transfer in the rat. Hepatology 2005, 42:1349-1354.
    • (2005) Hepatology , vol.42 , pp. 1349-1354
    • Hilmer, S.N.1    Cogger, V.C.2    Fraser, R.3    McLean, A.J.4    Sullivan, D.5    Le Couteur, D.G.6
  • 48
    • 0021233809 scopus 로고
    • Aging-associated pancreatic exocrine insufficiency in the unanesthetized rat
    • Hollander D., Dadufalza V.D. Aging-associated pancreatic exocrine insufficiency in the unanesthetized rat. Gerontology 1984, 30:218-222.
    • (1984) Gerontology , vol.30 , pp. 218-222
    • Hollander, D.1    Dadufalza, V.D.2
  • 50
    • 29244465117 scopus 로고    scopus 로고
    • Fat as an endocrine organ: relationship to the metabolic syndrome
    • Hutley L., Prins J.B. Fat as an endocrine organ: relationship to the metabolic syndrome. Am. J. Med. Sci. 2005, 330:280-289.
    • (2005) Am. J. Med. Sci. , vol.330 , pp. 280-289
    • Hutley, L.1    Prins, J.B.2
  • 51
    • 0017178767 scopus 로고
    • Post-heparin plasma lipoprotein lipase and hepatic lipase in normal subjects and in patients with hypertriglyceridaemia: correlations to sex, age and various parameters of triglyceride metabolism
    • Huttunen J.K., Ehnholm C., Kekki M., Nikkila E.A. Post-heparin plasma lipoprotein lipase and hepatic lipase in normal subjects and in patients with hypertriglyceridaemia: correlations to sex, age and various parameters of triglyceride metabolism. Clin. Sci. Mol. Med. 1976, 50:249-260.
    • (1976) Clin. Sci. Mol. Med. , vol.50 , pp. 249-260
    • Huttunen, J.K.1    Ehnholm, C.2    Kekki, M.3    Nikkila, E.A.4
  • 57
    • 0033510899 scopus 로고    scopus 로고
    • Relationship between endogenous sex hormone levels, lipoproteins and coronary atherosclerosis in men undergoing coronary angiography
    • Kabakci G., Yildirir A., Can I., Unsal I., Erbas B. Relationship between endogenous sex hormone levels, lipoproteins and coronary atherosclerosis in men undergoing coronary angiography. Cardiology 1999, 92:221-225.
    • (1999) Cardiology , vol.92 , pp. 221-225
    • Kabakci, G.1    Yildirir, A.2    Can, I.3    Unsal, I.4    Erbas, B.5
  • 58
    • 0033849777 scopus 로고    scopus 로고
    • Obesity and insulin resistance
    • Kahn B.B., Flier J.S. Obesity and insulin resistance. J. Clin. Invest. 2000, 106:473-481.
    • (2000) J. Clin. Invest. , vol.106 , pp. 473-481
    • Kahn, B.B.1    Flier, J.S.2
  • 59
    • 2942544306 scopus 로고    scopus 로고
    • Changes in body weight and body fat distribution as risk factors for clinical diabetes in US men
    • Koh-Banerjee P., Wang Y., Hu F.B., Spiegelman D., Willett W.C., Rimm E.B. Changes in body weight and body fat distribution as risk factors for clinical diabetes in US men. Am. J. Epidemiol. 2004, 159:1150-1159.
    • (2004) Am. J. Epidemiol. , vol.159 , pp. 1150-1159
    • Koh-Banerjee, P.1    Wang, Y.2    Hu, F.B.3    Spiegelman, D.4    Willett, W.C.5    Rimm, E.B.6
  • 61
    • 0025230810 scopus 로고
    • Postprandial plasma retinyl ester response is greater in older subjects compared with younger subjects. Evidence for delayed plasma clearance of intestinal lipoproteins
    • Krasinski S.D., Cohn J.S., Schaefer E.J., Russell R.M. Postprandial plasma retinyl ester response is greater in older subjects compared with younger subjects. Evidence for delayed plasma clearance of intestinal lipoproteins. J. Clin. Invest. 1990, 85:883-892.
    • (1990) J. Clin. Invest. , vol.85 , pp. 883-892
    • Krasinski, S.D.1    Cohn, J.S.2    Schaefer, E.J.3    Russell, R.M.4
  • 62
    • 0016176637 scopus 로고
    • Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia
    • Krauss R.M., Levy R.I., Fredrickson D.S. Selective measurement of two lipase activities in postheparin plasma from normal subjects and patients with hyperlipoproteinemia. J. Clin. Invest. 1974, 54:1107-1124.
    • (1974) J. Clin. Invest. , vol.54 , pp. 1107-1124
    • Krauss, R.M.1    Levy, R.I.2    Fredrickson, D.S.3
  • 63
    • 0023665488 scopus 로고
    • Cholesterol metabolism and aging
    • Kreisberg R.A., Kasim S. Cholesterol metabolism and aging. Am. J. Med. 1987, 82:54-60.
    • (1987) Am. J. Med. , vol.82 , pp. 54-60
    • Kreisberg, R.A.1    Kasim, S.2
  • 64
    • 0025299299 scopus 로고
    • Gonadotrophin-releasing hormone and human chorionic gonadotrophin tests reveal that both hypothalamic and testicular endocrine functions are suppressed during acute prolonged physical exercise
    • Kujala U.M., Alen M., Huhtaniemi I.T. Gonadotrophin-releasing hormone and human chorionic gonadotrophin tests reveal that both hypothalamic and testicular endocrine functions are suppressed during acute prolonged physical exercise. Clin. Endocrinol. (Oxf.) 1990, 33:219-225.
    • (1990) Clin. Endocrinol. (Oxf.) , vol.33 , pp. 219-225
    • Kujala, U.M.1    Alen, M.2    Huhtaniemi, I.T.3
  • 67
    • 0031898907 scopus 로고    scopus 로고
    • The aging liver. Drug clearance and an oxygen diffusion barrier hypothesis
    • Le Couteur D.G., McLean A.J. The aging liver. Drug clearance and an oxygen diffusion barrier hypothesis. Clin. Pharmacokinet. 1998, 34:359-373.
    • (1998) Clin. Pharmacokinet. , vol.34 , pp. 359-373
    • Le Couteur, D.G.1    McLean, A.J.2
  • 69
    • 0037018753 scopus 로고    scopus 로고
    • Hepatic pseudocapillarisation and atherosclerosis in ageing
    • Le Couteur D.G., Fraser R., Cogger V.C., McLean A.J. Hepatic pseudocapillarisation and atherosclerosis in ageing. Lancet 2002, 359:1612-1615.
    • (2002) Lancet , vol.359 , pp. 1612-1615
    • Le Couteur, D.G.1    Fraser, R.2    Cogger, V.C.3    McLean, A.J.4
  • 72
    • 0033308715 scopus 로고    scopus 로고
    • Growth hormone (GH) therapy in GH-deficient adults influences the response to a dietary load of cholesterol and saturated fat in terms of cholesterol synthesis, but not serum low density lipoprotein cholesterol levels
    • Leonsson M., Oscarsson J., Bosaeus I., Lundgren B.K., Johannsson G., Wiklund O., Bengtsson B.A. Growth hormone (GH) therapy in GH-deficient adults influences the response to a dietary load of cholesterol and saturated fat in terms of cholesterol synthesis, but not serum low density lipoprotein cholesterol levels. J. Clin. Endocrinol. Metab. 1999, 84:1296-1303.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 1296-1303
    • Leonsson, M.1    Oscarsson, J.2    Bosaeus, I.3    Lundgren, B.K.4    Johannsson, G.5    Wiklund, O.6    Bengtsson, B.A.7
  • 73
    • 84865023727 scopus 로고    scopus 로고
    • Combination of low free testosterone and low vitamin D predicts mortality in older men referred for coronary angiography
    • Lerchbaum E., Pilz S., Boehm B.O., Grammer T.B., Obermayer-Pietsch B., Marz W. Combination of low free testosterone and low vitamin D predicts mortality in older men referred for coronary angiography. Clin. Endocrinol. (Oxf.) 2012, 77:475-483.
    • (2012) Clin. Endocrinol. (Oxf.) , vol.77 , pp. 475-483
    • Lerchbaum, E.1    Pilz, S.2    Boehm, B.O.3    Grammer, T.B.4    Obermayer-Pietsch, B.5    Marz, W.6
  • 74
    • 46149094162 scopus 로고    scopus 로고
    • Molecular mechanism of age-specific hepatic lipid accumulation in PPARalpha (+/-):LDLR (+/-) mice, an obese mouse model
    • Li Y., Sugiyama E., Yokoyama S., Jiang L., Tanaka N., Aoyama T. Molecular mechanism of age-specific hepatic lipid accumulation in PPARalpha (+/-):LDLR (+/-) mice, an obese mouse model. Lipids 2008, 43:301-312.
    • (2008) Lipids , vol.43 , pp. 301-312
    • Li, Y.1    Sugiyama, E.2    Yokoyama, S.3    Jiang, L.4    Tanaka, N.5    Aoyama, T.6
  • 75
    • 0020537615 scopus 로고
    • Lipoprotein receptors and cholesterol homeostasis
    • Mahley R.W., Innerarity T.L. Lipoprotein receptors and cholesterol homeostasis. Biochim. Biophys. Acta 1983, 737:197-222.
    • (1983) Biochim. Biophys. Acta , vol.737 , pp. 197-222
    • Mahley, R.W.1    Innerarity, T.L.2
  • 76
    • 67649717981 scopus 로고    scopus 로고
    • The effects of endogenous and exogenous androgens on cardiovascular disease risk factors and progression
    • Manolakou P., Angelopoulou R., Bakoyiannis C., Bastounis E. The effects of endogenous and exogenous androgens on cardiovascular disease risk factors and progression. Reprod. Biol. Endocrinol. 2009, 7:44.
    • (2009) Reprod. Biol. Endocrinol. , vol.7 , pp. 44
    • Manolakou, P.1    Angelopoulou, R.2    Bakoyiannis, C.3    Bastounis, E.4
  • 77
    • 2642572647 scopus 로고    scopus 로고
    • Aging biology and geriatric clinical pharmacology
    • McLean A.J., Le Couteur D.G. Aging biology and geriatric clinical pharmacology. Pharmacol. Rev. 2004, 56:163-184.
    • (2004) Pharmacol. Rev. , vol.56 , pp. 163-184
    • McLean, A.J.1    Le Couteur, D.G.2
  • 79
    • 0031749189 scopus 로고    scopus 로고
    • Heterogeneity of apolipoprotein B-100-containing lipoproteins: what we have learnt from kinetic studies
    • Millar J.S., Packard C.J. Heterogeneity of apolipoprotein B-100-containing lipoproteins: what we have learnt from kinetic studies. Curr. Opin. Lipidol. 1998, 9:197-202.
    • (1998) Curr. Opin. Lipidol. , vol.9 , pp. 197-202
    • Millar, J.S.1    Packard, C.J.2
  • 82
    • 84860877671 scopus 로고    scopus 로고
    • Testosterone and cardiovascular disease in men
    • Morris P.D., Channer K.S. Testosterone and cardiovascular disease in men. Asian J. Androl. 2012, 14:428-435.
    • (2012) Asian J. Androl. , vol.14 , pp. 428-435
    • Morris, P.D.1    Channer, K.S.2
  • 83
    • 0032479423 scopus 로고    scopus 로고
    • Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner
    • Motojima K., Passilly P., Peters J.M., Gonzalez F.J., Latruffe N. Expression of putative fatty acid transporter genes are regulated by peroxisome proliferator-activated receptor alpha and gamma activators in a tissue- and inducer-specific manner. J. Biol. Chem. 1998, 273:16710-16714.
    • (1998) J. Biol. Chem. , vol.273 , pp. 16710-16714
    • Motojima, K.1    Passilly, P.2    Peters, J.M.3    Gonzalez, F.J.4    Latruffe, N.5
  • 85
    • 3242698031 scopus 로고    scopus 로고
    • Expression and function of class B scavenger receptor type I on both apical and basolateral sides of the plasma membrane of polarized testicular Sertoli cells of the rat
    • Nakagawa A., Nagaosa K., Hirose T., Tsuda K., Hasegawa K., Shiratsuchi A., Nakanishi Y. Expression and function of class B scavenger receptor type I on both apical and basolateral sides of the plasma membrane of polarized testicular Sertoli cells of the rat. Dev. Growth Differ. 2004, 46:283-298.
    • (2004) Dev. Growth Differ. , vol.46 , pp. 283-298
    • Nakagawa, A.1    Nagaosa, K.2    Hirose, T.3    Tsuda, K.4    Hasegawa, K.5    Shiratsuchi, A.6    Nakanishi, Y.7
  • 88
    • 0001153850 scopus 로고
    • Relationship between plasma triglycerides and removal of chylomicrons
    • Nestel P.J. Relationship between plasma triglycerides and removal of chylomicrons. J. Clin. Invest. 1964, 43:943-949.
    • (1964) J. Clin. Invest. , vol.43 , pp. 943-949
    • Nestel, P.J.1
  • 89
    • 0034668205 scopus 로고    scopus 로고
    • Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis
    • Neve B.P., Fruchart J.C., Staels B. Role of the peroxisome proliferator-activated receptors (PPAR) in atherosclerosis. Biochem. Pharmacol. 2000, 60:1245-1250.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 1245-1250
    • Neve, B.P.1    Fruchart, J.C.2    Staels, B.3
  • 90
    • 0026644348 scopus 로고
    • Aging and total cholesterol levels: cohort, period, and survivorship effects
    • Newschaffer C.J., Bush T.L., Hale W.E. Aging and total cholesterol levels: cohort, period, and survivorship effects. Am. J. Epidemiol. 1992, 136:23-34.
    • (1992) Am. J. Epidemiol. , vol.136 , pp. 23-34
    • Newschaffer, C.J.1    Bush, T.L.2    Hale, W.E.3
  • 91
    • 0029006561 scopus 로고
    • Adverse effects of psychosocial stress on gonadal function and insulin levels in middle-aged males
    • Nilsson P.M., Moller L., Solstad K. Adverse effects of psychosocial stress on gonadal function and insulin levels in middle-aged males. J. Intern. Med. 1995, 237:479-486.
    • (1995) J. Intern. Med. , vol.237 , pp. 479-486
    • Nilsson, P.M.1    Moller, L.2    Solstad, K.3
  • 92
    • 84910001969 scopus 로고    scopus 로고
    • Associations between insulin resistance, free fatty acids, and oocyte quality in polycystic ovary syndrome during in vitro fertilization
    • Niu Z., Lin N., Gu R., Sun Y., Feng Y. Associations between insulin resistance, free fatty acids, and oocyte quality in polycystic ovary syndrome during in vitro fertilization. J. Clin. Endocrinol. Metab. 2014, 99:2269-2276.
    • (2014) J. Clin. Endocrinol. Metab. , vol.99 , pp. 2269-2276
    • Niu, Z.1    Lin, N.2    Gu, R.3    Sun, Y.4    Feng, Y.5
  • 93
    • 0029092276 scopus 로고
    • Growth hormone specifically stimulates the expression of low density lipoprotein receptors in human hepatoma cells
    • Parini P., Angelin B., Lobie P.E., Norstedt G., Rudling M. Growth hormone specifically stimulates the expression of low density lipoprotein receptors in human hepatoma cells. Endocrinology 1995, 136:3767-3773.
    • (1995) Endocrinology , vol.136 , pp. 3767-3773
    • Parini, P.1    Angelin, B.2    Lobie, P.E.3    Norstedt, G.4    Rudling, M.5
  • 94
    • 0032893056 scopus 로고    scopus 로고
    • Cholesterol and lipoprotein metabolism in aging: reversal of hypercholesterolemia by growth hormone treatment in old rats
    • Parini P., Angelin B., Rudling M. Cholesterol and lipoprotein metabolism in aging: reversal of hypercholesterolemia by growth hormone treatment in old rats. Arterioscler. Thromb. Vasc. Biol. 1999, 19:832-839.
    • (1999) Arterioscler. Thromb. Vasc. Biol. , vol.19 , pp. 832-839
    • Parini, P.1    Angelin, B.2    Rudling, M.3
  • 95
    • 77952708884 scopus 로고    scopus 로고
    • Apolipoprotein D in lipid metabolism and its functional implication in atherosclerosis and aging
    • Perdomo G., Henry Dong H. Apolipoprotein D in lipid metabolism and its functional implication in atherosclerosis and aging. Aging (Milano) 2009, 1:17-27.
    • (2009) Aging (Milano) , vol.1 , pp. 17-27
    • Perdomo, G.1    Henry Dong, H.2
  • 96
    • 0030766476 scopus 로고    scopus 로고
    • Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice
    • Peters J.M., Hennuyer N., Staels B., Fruchart J.C., Fievet C., Gonzalez F.J., Auwerx J. Alterations in lipoprotein metabolism in peroxisome proliferator-activated receptor alpha-deficient mice. J. Biol. Chem. 1997, 272:27307-27312.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27307-27312
    • Peters, J.M.1    Hennuyer, N.2    Staels, B.3    Fruchart, J.C.4    Fievet, C.5    Gonzalez, F.J.6    Auwerx, J.7
  • 97
    • 0028175550 scopus 로고
    • The association of hypotestosteronemia with coronary artery disease in men
    • Phillips G.B., Pinkernell B.H., Jing T.Y. The association of hypotestosteronemia with coronary artery disease in men. Arterioscler. Thromb. 1994, 14:701-706.
    • (1994) Arterioscler. Thromb. , vol.14 , pp. 701-706
    • Phillips, G.B.1    Pinkernell, B.H.2    Jing, T.Y.3
  • 98
    • 0033695265 scopus 로고    scopus 로고
    • Emerging concepts in metabolic abnormalities associated with coronary artery disease
    • Plutzky J. Emerging concepts in metabolic abnormalities associated with coronary artery disease. Curr. Opin. Cardiol. 2000, 15:416-421.
    • (2000) Curr. Opin. Cardiol. , vol.15 , pp. 416-421
    • Plutzky, J.1
  • 101
    • 0029821371 scopus 로고    scopus 로고
    • Restoration of growth hormone (GH) response to GH-releasing hormone in elderly and obese subjects by acute pharmacological reduction of plasma free fatty acids
    • Pontiroli A.E., Manzoni M.F., Malighetti M.E., Lanzi R. Restoration of growth hormone (GH) response to GH-releasing hormone in elderly and obese subjects by acute pharmacological reduction of plasma free fatty acids. J. Clin. Endocrinol. Metab. 1996, 81:3998-4001.
    • (1996) J. Clin. Endocrinol. Metab. , vol.81 , pp. 3998-4001
    • Pontiroli, A.E.1    Manzoni, M.F.2    Malighetti, M.E.3    Lanzi, R.4
  • 102
    • 0024160877 scopus 로고
    • Banting lecture 1988. Role of insulin resistance in human disease
    • Reaven G.M. Banting lecture 1988. Role of insulin resistance in human disease. Diabetes 1988, 37:1595-1607.
    • (1988) Diabetes , vol.37 , pp. 1595-1607
    • Reaven, G.M.1
  • 104
    • 0030987347 scopus 로고    scopus 로고
    • Growth hormone and bile acid synthesis. Key role for the activity of hepatic microsomal cholesterol 7alpha-hydroxylase in the rat
    • Rudling M., Parini P., Angelin B. Growth hormone and bile acid synthesis. Key role for the activity of hepatic microsomal cholesterol 7alpha-hydroxylase in the rat. J. Clin. Invest. 1997, 99:2239-2245.
    • (1997) J. Clin. Invest. , vol.99 , pp. 2239-2245
    • Rudling, M.1    Parini, P.2    Angelin, B.3
  • 106
    • 0024596517 scopus 로고
    • Plasma lipoproteins in healthy octogenarians: lack of reduced high density lipoprotein cholesterol levels: results from the Framingham Heart Study
    • Schaefer E.J., Moussa P.B., Wilson P.W., McGee D., Dallal G., Castelli W.P. Plasma lipoproteins in healthy octogenarians: lack of reduced high density lipoprotein cholesterol levels: results from the Framingham Heart Study. Metabolism 1989, 38:293-296.
    • (1989) Metabolism , vol.38 , pp. 293-296
    • Schaefer, E.J.1    Moussa, P.B.2    Wilson, P.W.3    McGee, D.4    Dallal, G.5    Castelli, W.P.6
  • 107
    • 7244227781 scopus 로고    scopus 로고
    • Effects of androgen substitution on lipid profile in the adult and aging hypogonadal male
    • Schleich F., Legros J.J. Effects of androgen substitution on lipid profile in the adult and aging hypogonadal male. Eur. J. Endocrinol. 2004, 151:415-424.
    • (2004) Eur. J. Endocrinol. , vol.151 , pp. 415-424
    • Schleich, F.1    Legros, J.J.2
  • 108
    • 0037188551 scopus 로고    scopus 로고
    • Scavenger endothelial cells of vertebrates: a nonperipheral leukocyte system for high-capacity elimination of waste macromolecules
    • Seternes T., Sorensen K., Smedsrod B. Scavenger endothelial cells of vertebrates: a nonperipheral leukocyte system for high-capacity elimination of waste macromolecules. Proc. Natl. Acad. Sci. U. S. A. 2002, 99:7594-7597.
    • (2002) Proc. Natl. Acad. Sci. U. S. A. , vol.99 , pp. 7594-7597
    • Seternes, T.1    Sorensen, K.2    Smedsrod, B.3
  • 110
    • 0030465875 scopus 로고    scopus 로고
    • Fat and carbohydrate metabolism during exercise in elderly and young subjects
    • Sial S., Coggan A.R., Carroll R., Goodwin J., Klein S. Fat and carbohydrate metabolism during exercise in elderly and young subjects. Am. J. Physiol. 1996, 271:E983-E989.
    • (1996) Am. J. Physiol. , vol.271 , pp. E983-E989
    • Sial, S.1    Coggan, A.R.2    Carroll, R.3    Goodwin, J.4    Klein, S.5
  • 111
    • 0026634963 scopus 로고
    • Effects of growth hormone on apolipoprotein-B (apoB) messenger ribonucleic acid editing, and apoB 48 and apoB 100 synthesis and secretion in the rat liver
    • Sjoberg A., Oscarsson J., Bostrom K., Innerarity T.L., Eden S., Olofsson S.O. Effects of growth hormone on apolipoprotein-B (apoB) messenger ribonucleic acid editing, and apoB 48 and apoB 100 synthesis and secretion in the rat liver. Endocrinology 1992, 130:3356-3364.
    • (1992) Endocrinology , vol.130 , pp. 3356-3364
    • Sjoberg, A.1    Oscarsson, J.2    Bostrom, K.3    Innerarity, T.L.4    Eden, S.5    Olofsson, S.O.6
  • 112
    • 0028127770 scopus 로고
    • Continuous but not intermittent administration of growth hormone to hypophysectomized rats increases apolipoprotein-E secretion from cultured hepatocytes
    • Sjoberg A., Oscarsson J., Eden S., Olofsson S.O. Continuous but not intermittent administration of growth hormone to hypophysectomized rats increases apolipoprotein-E secretion from cultured hepatocytes. Endocrinology 1994, 134:790-798.
    • (1994) Endocrinology , vol.134 , pp. 790-798
    • Sjoberg, A.1    Oscarsson, J.2    Eden, S.3    Olofsson, S.O.4
  • 114
    • 0019207594 scopus 로고
    • Decreased pulsatile release of growth hormone in old male rats
    • Sonntag W.E., Steger R.W., Forman L.J., Meites J. Decreased pulsatile release of growth hormone in old male rats. Endocrinology 1980, 107:1875-1879.
    • (1980) Endocrinology , vol.107 , pp. 1875-1879
    • Sonntag, W.E.1    Steger, R.W.2    Forman, L.J.3    Meites, J.4
  • 115
    • 0025736957 scopus 로고
    • Age-related changes in the metabolism of cholesterol in rat liver microsomes
    • Stahlberg D., Angelin B., Einarsson K. Age-related changes in the metabolism of cholesterol in rat liver microsomes. Lipids 1991, 26:349-352.
    • (1991) Lipids , vol.26 , pp. 349-352
    • Stahlberg, D.1    Angelin, B.2    Einarsson, K.3
  • 118
    • 0033968423 scopus 로고    scopus 로고
    • Changes in protein, carbohydrate, and fat metabolism with aging: possible role of insulin
    • Tessari P. Changes in protein, carbohydrate, and fat metabolism with aging: possible role of insulin. Nutr. Rev. 2000, 58:11-19.
    • (2000) Nutr. Rev. , vol.58 , pp. 11-19
    • Tessari, P.1
  • 119
    • 0033924298 scopus 로고    scopus 로고
    • Lipid metabolism in the elderly
    • Toth M.J., Tchernof A. Lipid metabolism in the elderly. Eur. J. Clin. Nutr. 2000, 54(Suppl. 3):S121-S125.
    • (2000) Eur. J. Clin. Nutr. , vol.54 , pp. S121-S125
    • Toth, M.J.1    Tchernof, A.2
  • 120
    • 34548165798 scopus 로고    scopus 로고
    • Sudden cardiac death: epidemiology, mechanisms, and therapy
    • Turakhia M., Tseng Z.H. Sudden cardiac death: epidemiology, mechanisms, and therapy. Curr. Probl. Cardiol. 2007, 32:501-546.
    • (2007) Curr. Probl. Cardiol. , vol.32 , pp. 501-546
    • Turakhia, M.1    Tseng, Z.H.2
  • 121
    • 1842834450 scopus 로고    scopus 로고
    • Differential contribution of testosterone and estradiol in the determination of cholesterol and lipoprotein profile in healthy middle-aged men
    • Van Pottelbergh I., Braeckman L., De Bacquer D., De Backer G., Kaufman J.M. Differential contribution of testosterone and estradiol in the determination of cholesterol and lipoprotein profile in healthy middle-aged men. Atherosclerosis 2003, 166:95-102.
    • (2003) Atherosclerosis , vol.166 , pp. 95-102
    • Van Pottelbergh, I.1    Braeckman, L.2    De Bacquer, D.3    De Backer, G.4    Kaufman, J.M.5
  • 123
    • 0035170229 scopus 로고    scopus 로고
    • High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport
    • von Eckardstein A., Nofer J.R., Assmann G. High density lipoproteins and arteriosclerosis. Role of cholesterol efflux and reverse cholesterol transport. Arterioscler. Thromb. Vasc. Biol. 2001, 21:13-27.
    • (2001) Arterioscler. Thromb. Vasc. Biol. , vol.21 , pp. 13-27
    • von Eckardstein, A.1    Nofer, J.R.2    Assmann, G.3
  • 124
    • 0028036723 scopus 로고
    • Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element
    • Vu-Dac N., Schoonjans K., Laine B., Fruchart J.C., Auwerx J., Staels B. Negative regulation of the human apolipoprotein A-I promoter by fibrates can be attenuated by the interaction of the peroxisome proliferator-activated receptor with its response element. J. Biol. Chem. 1994, 269:31012-31018.
    • (1994) J. Biol. Chem. , vol.269 , pp. 31012-31018
    • Vu-Dac, N.1    Schoonjans, K.2    Laine, B.3    Fruchart, J.C.4    Auwerx, J.5    Staels, B.6
  • 125
    • 0029119082 scopus 로고
    • Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor
    • Vu-Dac N., Schoonjans K., Kosykh V., Dallongeville J., Fruchart J.C., Staels B., Auwerx J. Fibrates increase human apolipoprotein A-II expression through activation of the peroxisome proliferator-activated receptor. J. Clin. Invest. 1995, 96:741-750.
    • (1995) J. Clin. Invest. , vol.96 , pp. 741-750
    • Vu-Dac, N.1    Schoonjans, K.2    Kosykh, V.3    Dallongeville, J.4    Fruchart, J.C.5    Staels, B.6    Auwerx, J.7
  • 126
    • 69849112228 scopus 로고    scopus 로고
    • Interrelationships among HDL metabolism, aging, and atherosclerosis
    • Walter M. Interrelationships among HDL metabolism, aging, and atherosclerosis. Arterioscler. Thromb. Vasc. Biol. 2009, 29:1244-1250.
    • (2009) Arterioscler. Thromb. Vasc. Biol. , vol.29 , pp. 1244-1250
    • Walter, M.1
  • 128
    • 0023950672 scopus 로고
    • Effect of ageing on the gastro-intestinal transit of a lactulose-supplemented mixed solid-liquid meal in humans
    • Wegener M., Borsch G., Schaffstein J., Luth I., Rickels R., Ricken D. Effect of ageing on the gastro-intestinal transit of a lactulose-supplemented mixed solid-liquid meal in humans. Digestion 1988, 39:40-46.
    • (1988) Digestion , vol.39 , pp. 40-46
    • Wegener, M.1    Borsch, G.2    Schaffstein, J.3    Luth, I.4    Rickels, R.5    Ricken, D.6
  • 129
    • 0023481281 scopus 로고
    • Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E
    • Weintraub M.S., Eisenberg S., Breslow J.L. Dietary fat clearance in normal subjects is regulated by genetic variation in apolipoprotein E. J. Clin. Invest. 1987, 80:1571-1577.
    • (1987) J. Clin. Invest. , vol.80 , pp. 1571-1577
    • Weintraub, M.S.1    Eisenberg, S.2    Breslow, J.L.3
  • 130
    • 84973552382 scopus 로고    scopus 로고
    • Association of serum testosterone with lipid abnormalities in patients with angiographically proven coronary artery disease
    • Wickramatilake C.M., Mohideen M.R., Pathirana C. Association of serum testosterone with lipid abnormalities in patients with angiographically proven coronary artery disease. Ind. J. Endocrinol. Metab. 2013, 17:1061-1065.
    • (2013) Ind. J. Endocrinol. Metab. , vol.17 , pp. 1061-1065
    • Wickramatilake, C.M.1    Mohideen, M.R.2    Pathirana, C.3
  • 131
    • 0037396460 scopus 로고    scopus 로고
    • Androgens and coronary artery disease
    • Wu F.C., von Eckardstein A. Androgens and coronary artery disease. Endocr. Rev. 2003, 24:183-217.
    • (2003) Endocr. Rev. , vol.24 , pp. 183-217
    • Wu, F.C.1    von Eckardstein, A.2
  • 132
    • 21844435990 scopus 로고    scopus 로고
    • Age-related decrease in expression of peroxisome proliferator-activated receptor alpha and its effects on development of dyslipidemia
    • Ye P., Wang Z.J., Zhang X.J., Zhao Y.L. Age-related decrease in expression of peroxisome proliferator-activated receptor alpha and its effects on development of dyslipidemia. Chin. Med. J. (Engl.) 2005, 118:1093-1098.
    • (2005) Chin. Med. J. (Engl.) , vol.118 , pp. 1093-1098
    • Ye, P.1    Wang, Z.J.2    Zhang, X.J.3    Zhao, Y.L.4
  • 134
    • 0032583843 scopus 로고    scopus 로고
    • The association of low plasma testosterone level with coronary artery disease in Chinese men
    • Zhao S.P., Li X.P. The association of low plasma testosterone level with coronary artery disease in Chinese men. Int. J. Cardiol. 1998, 63:161-164.
    • (1998) Int. J. Cardiol. , vol.63 , pp. 161-164
    • Zhao, S.P.1    Li, X.P.2
  • 135
    • 0030693103 scopus 로고    scopus 로고
    • Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former multiple risk factor intervention trial participants
    • Zmuda J.M., Cauley J.A., Kriska A., Glynn N.W., Gutai J.P., Kuller L.H. Longitudinal relation between endogenous testosterone and cardiovascular disease risk factors in middle-aged men. A 13-year follow-up of former multiple risk factor intervention trial participants. Am. J. Epidemiol. 1997, 146:609-617.
    • (1997) Am. J. Epidemiol. , vol.146 , pp. 609-617
    • Zmuda, J.M.1    Cauley, J.A.2    Kriska, A.3    Glynn, N.W.4    Gutai, J.P.5    Kuller, L.H.6
  • 136
    • 0025050724 scopus 로고
    • Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity
    • Zumoff B., Strain G.W., Miller L.K., Rosner W., Senie R., Seres D.S., Rosenfeld R.S. Plasma free and non-sex-hormone-binding-globulin-bound testosterone are decreased in obese men in proportion to their degree of obesity. J. Clin. Endocrinol. Metab. 1990, 71:929-931.
    • (1990) J. Clin. Endocrinol. Metab. , vol.71 , pp. 929-931
    • Zumoff, B.1    Strain, G.W.2    Miller, L.K.3    Rosner, W.4    Senie, R.5    Seres, D.S.6    Rosenfeld, R.S.7


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