Quantifying mRNA targeting to P-bodies in living human cells reveals their dual role in mRNA decay and storage

Journal of Cell Science

Volumn 127, Issue 20, 2014, Pages 4443-4456

  Aizer, Adva ^a   Kalo, Alon ^a   Kafri, Pinhas ^a   Shraga, Amit ^a   Ben Yishay, Rakefet ^a   Jacob, Avi ^a   Kinor, Noa ^a   Shav Tal, Yaron ^a  

^a BAR ILAN UNIVERSITY   (Israel)

Author keywords

P body; RNA dynamics; RNA quantification

Indexed keywords

CYCLOHEXIMIDE; DOXYCYCLINE; MESSENGER RNA; POLYADENYLIC ACID; PONASTERONE A; AMINO ACID; DCP2 PROTEIN, HUMAN; RIBONUCLEASE;

3' UNTRANSLATED REGION; ANIMAL CELL; ARTICLE; AUTOPHAGOSOME; CELL COMPONENT; CELL POPULATION; CYTOPLASM; CYTOPLASMIC PROCESSING BODY; DEGRADATION; FIBROBLAST; FLUORESCENCE IN SITU HYBRIDIZATION; FLUORESCENCE RECOVERY AFTER PHOTOBLEACHING; GENE EXPRESSION SYSTEM; HUMAN; HUMAN CELL; IMMUNOFLUORESCENCE; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; OSMOTIC STRESS; RNA METABOLISM; STORAGE; TIME LAPSE IMAGING; TRANSCRIPTION INITIATION; U2OS CELL LINE; WESTERN BLOTTING; CELL LINE; CELL STRUCTURE; DEFICIENCY; GENE SILENCING; GENETICS; METABOLISM; PHYSIOLOGICAL STRESS; PROTEIN SYNTHESIS; RNA STABILITY;

EUKARYOTA; MAMMALIA;

AMINO ACIDS; CELL LINE; CELLULAR STRUCTURES; CYTOPLASM; ENDORIBONUCLEASES; GENE KNOCKDOWN TECHNIQUES; HUMANS; PROTEIN BIOSYNTHESIS; RNA STABILITY; RNA, MESSENGER; STRESS, PHYSIOLOGICAL; TIME-LAPSE IMAGING;

EID: 84918594125     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.152975     Document Type: Article

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