Impact of HLA-driven HIV adaptation on virulence in populations of high HIV seroprevalence

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 50, 2014, Pages E5393-E5400

  Payne, Rebecca ^a   Muenchhoff, Maximilian ^a   Mann, Jaclyn ^b   Roberts, Hannah E ^c,d   Matthews, Philippa ^a   Adland, Emily ^a   Hempenstal, Allison ^a   Huang, Kuan Hsiang ^c,d   Brockman, Mark ^e,f   Brumme, Zabrina ^e,f   Sinclair, Marc ^a   Miura, Toshiyuki ^g   Frater, John ^c,d,h   Essex, Myron ^i,j   Shapiro, Roger ^i,j   Walker, Bruce D ^b,k   Ndung'u, Thumbi ^b,k   McLean, Angela R ^c,l   Carlson, Jonathan M ^m   Goulder, Philip J R ^a,b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF KWAZULU NATAL   (South Africa)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF OXFORD   (United Kingdom)

^e SIMON FRASER UNIVERSITY   (Canada)

^f BRITISH COLUMBIA CENTRE FOR EXCELLENCE IN HIV AIDS   (Canada)

^g VIIV HEALTHCARE   (United States)

^h NATIONAL INSTITUTES OF HEALTH   (United States)

ⁱ BOTSWANA HARVARD AIDS INSTITUTE PARTNERSHIP   (Botswana)

^j HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^k MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^l UNIVERSITY OF OXFORD   (United Kingdom)

^m MICROSOFT RESEARCH   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

HLA ANTIGEN; HLA B ANTIGEN; HLA B39 ANTIGEN; HLA B42 ANTIGEN; HLA B57 ANTIGEN; HLA B58 ANTIGEN; HLA B81 ANTIGEN; NEVIRAPINE; UNCLASSIFIED DRUG; VIRUS RNA; ZIDOVUDINE;

ADAPTATION; ADULT; ANTIVIRAL THERAPY; ARTICLE; BOTSWANA; CD4 LYMPHOCYTE COUNT; CONTROLLED STUDY; DISEASE COURSE; EPIDEMIC; FEMALE; HLA SYSTEM; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HUMAN IMMUNODEFICIENCY VIRUS PREVALENCE; MAJOR CLINICAL STUDY; NONHUMAN; NUCLEOTIDE SEQUENCE; VIRUS ADAPTATION; VIRUS LOAD; VIRUS MUTATION; VIRUS REPLICATION; VIRUS VIRULENCE; COHORT ANALYSIS; DNA SEQUENCE; GENETICS; HIV INFECTIONS; IMMUNOLOGY; MOLECULAR EVOLUTION; MOLECULAR GENETICS; PATHOGENICITY; SOUTH AFRICA; TRANSMISSION; VIRULENCE;

ADAPTATION, BIOLOGICAL; ADULT; BASE SEQUENCE; BOTSWANA; COHORT STUDIES; EVOLUTION, MOLECULAR; HIV; HIV INFECTIONS; HLA-B ANTIGENS; HUMANS; MOLECULAR SEQUENCE DATA; SEQUENCE ANALYSIS, DNA; SEROEPIDEMIOLOGIC STUDIES; SOUTH AFRICA; VIRULENCE;

EID: 84918592939     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1413339111     Document Type: Article

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