Frequent and variable cytotoxic-T-lymphocyte escape-associated fitness costs in the human immunodeficiency virus type 1 subtype B gag proteins

Journal of Virology

Volumn 87, Issue 7, 2013, Pages 3952-3965

  Boutwell, Christian L ^a   Carlson, Jonathan M ^b   Lin, Tien Ho ^b   Seese, Aaron ^a   Power, Karen A ^a   Peng, Jian ^b   Tang, Yanhua ^a   Brumme, Zabrina L ^c,d   Heckerman, David ^b   Schneidewind, Arne ^e   Allen, Todd M ^a  

^a MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^b MICROSOFT RESEARCH   (United States)

^c SIMON FRASER UNIVERSITY   (Canada)

^d BRITISH COLUMBIA CENTRE FOR EXCELLENCE IN HIV AIDS   (Canada)

^e UNIVERSITY HOSPITAL REGENSBURG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GAG PROTEIN; HLA ANTIGEN CLASS 1;

ALLELE; ANTIVIRAL RESISTANCE; ARTICLE; COMPUTER MODEL; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; ENTROPY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; IMMUNE RESPONSE; IN VITRO STUDY; MUTATION; NONHUMAN; PLASMID; PRIORITY JOURNAL; THERMODYNAMICS; VIRUS REPLICATION;

CLONING, MOLECULAR; DNA PRIMERS; GAG GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; GENETIC FITNESS; HIV-1; HUMANS; MUTAGENESIS, SITE-DIRECTED; MUTATION; PLASMIDS; REAL-TIME POLYMERASE CHAIN REACTION; T-LYMPHOCYTES, CYTOTOXIC; THERMODYNAMICS; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84875527661     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.03233-12     Document Type: Article

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