Implementing early diagnosis and treatment: Programmatic considerations

Current Opinion in HIV and AIDS

Volumn 10, Issue 1, 2015, Pages 69-75

  Phanuphak, Praphan ^a   Lo, Ying Ru ^b  

^a CHULALONGKORN UNIVERSITY   (Thailand)

^b WORLD HEALTH ORGANIZATION   (Switzerland)

Author keywords

Antiretroviral therapy; HIV cure; HIV testing

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIRETROVIRUS AGENT;

ANTIVIRAL THERAPY; CLINICAL ASSESSMENT; COUNSELING; DISEASE SEVERITY; EARLY DIAGNOSIS; HIV TEST; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; REVIEW; HIV INFECTIONS;

ANTI-RETROVIRAL AGENTS; COUNSELING; EARLY DIAGNOSIS; HIV INFECTIONS; HUMANS;

EID: 84918570243     PISSN: 1746630X     EISSN: 17466318     Source Type: Journal    
DOI: 10.1097/COH.0000000000000126     Document Type: Review

References (55)

1. Persaud D, Gay H, Ziemniak C, et al. Absence of detectable HIV-1 viremia after treatment cessation in an infant. N Engl J Med 2013; 369:1828-1835
2. Lewin SR, Deeks SG, Barre-Sinoussi F. Towards a cure for HIV-are we making progress? Lancet 2014; 384:209-211.
3. National Institute of Allergy and Infectious Diseases. 'Mississippi baby' now has detectable HIV, researchers find. NIH News July 10, 2014. In: NIH News; July 10, 2014; 2014. http://www.niaid.nih.gov/news/newsreleases/2014/Pages/MississippiBabyHIV.aspx. [Accessed 19 July 2014]
4. Deeks SG, Autran B, Berkhout B, et al. Towards an HIV cure: a global scientific strategy. Nat Rev Immunol 2012; 12:607-614.
5. Katlama C, Deeks SG, Autran B, et al. Barriers to a cure for HIV: new ways to target and eradicate HIV-1 reservoirs. Lancet 2013; 381:2109-2117.
6. Cohen MS, Shaw GM, McMichael AJ, Haynes BF. Acute HIV-1 Infection. N Engl J Med 2011; 364:1943-1954.
7. Ananworanich J, Chomchey N, Phanuphak N, et al. on behalf of the RV254/SEARCH 010 Study Group. Early ART intervention restricts the seeding of the HIV reservoir in long lived central memory CD4 T cells [abstract 47]. In: 20th Conferences on Retroviruses and Opportunistic Infections; March 3-6. Atlanta, United States of America; 2013.
8. Pires A, Hardy G, Gazzard B, et al. Initiation of antiretroviral therapy during recent HIV-1 infection results in lower residual viral reservoirs. J Acquir Immune Defic Syndr 2004; 36:783-790.
9. Schmid A, Gianella S, von Wyl V, et al. Profound depletion of HIV-1 transcription in patients initiating antiretroviral therapy during acute infection. PLoS One 2010; 5:e13310.
10. Gianella S, von Wyl V, Fischer M, et al. Effect of early antiretroviral therapy during primary HIV-1 infection on cell-associated HIV-1 DNA and plasma HIV-1 RNA. Antivir Ther 2011; 16:535-545.
11. Lodi S, Meyer L, Kelleher AD, et al. Immunovirologic control 24 months after interruption of antiretroviral therapy initiated close to HIV seroconversion. Arch Intern Med 2012; 172:1252-1255.
12. Saez-Cirion A, Bacchus C, Hocqueloux L, et al. Posttreatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study. PLoS Pathog 2013; 9:e1003211.
13. Marrazzo JM, Del Rio C, Holtgrave DR, et al. HIV prevention in clinical care settings: 2014 recommendations of the International Antiviral Society - USA Panel. JAMA 2014; 312:390-409.
14. Kato M, Granich R, Bui DD, et al. The potential impact of expanding antiretroviral therapy and combination prevention in Vietnam: towards elimination of HIV transmission. J Acquir Immune Defic Syndr 2013; 63:e142-149.
15. Suthar AB, Ford N, Bachanas PJ, et al. Towards universal voluntary HIV testing and counselling: a systematic review and meta-analysis of community-based approaches. PLoS Med 2013; 10:e1001496.
16. WHO. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Geneva, Switzerland: World Health Organization; 2013. http://apps.who.int/iris/bitstream/10665/85321/1/9789241505727-eng.pdf?ua=1. [Accessed 5 October 2014]
17. Vun MC, Fujita M, Rathavy T, et al. Achieving universal access and moving towards elimination of new HIV infections in Cambodia. J Int AIDS Soc 2014; 17:18905.
18. Johnson C, Baggaley R, Forsythe S, et al. Realizing the potential for HIV self-testing. AIDS Behav 2014; 18 (Suppl 4):391-395.
19. WHO. Consolidated guidelines on HIV prevention, diagnosis, treatment and care for key populations. Geneva, Switzerland: World Health Organization; 2014. http://www.who.int/hiv/pub/guidelines/keypopulations/en/. [Accessed 1 October 2014]
20. WHO. Adolescent HIV testing, counselling and care. Implementation guidance for health providers and planners. Geneva, Switzerland: World Health Organization; 2014. http://www.who.int/maternal-child-adolescent/documents/hiv-testing-counselling/en/. [Accessed 5 October 2014]
21. WHO. HIV and adolescents: Guidance for HIV testing and counselling and care for adolescents living with HIV. Guidance document. Geneva, Switzerland: World Health Organization; 2013. http://www.who.int/hiv/pub/guide-lines/adolescents/en/. [Accessed 5 October 2014]
22. Lo YR, Kato M, Phanuphak N, et al. Challenges and potential barriers to the uptake of antiretroviral-based prevention in Asia and the Pacific region. Sex Health 2014; 11:126-136.
23. Ananworanich J, Fletcher JL, Pinyakorn S, et al. A novel acute HIV infection staging system based on 4th generation immunoassay. Retrovirology 2013; 10:56.
24. Avila FD, Althoff KN, Mugglin C, et al., IeDea, Collaborations A.R.T.C. Immunodeficiency at the start of combination antiretroviral therapy in low-, middle-, and high-income countries. J Acquir Immune Defic Syndr 2014; 65:e8-16.
25. Ministry of Public Health Thailand. National AIDS Program (NAP) Report Thailand. Bangkok, Thailand; 2012.
26. van Griensven F, Phanuphak N, Srithanaviboonchai K. Biomedical HIV prevention research and epidemic control in Thailand: two sides of the same coin. Sex Health 2014; 11:180-199.
27. Government of Vietnam. Vietnam AIDS response progress report 2014. National committee for AIDS, drugs and prostitution prevention and control, Government of Vietnam: Hanoi, Viet Nam. http://www.aidsdatahub.org/sites/default/files/publication/Vietnam-narrative-report-2014.pdf. [Accessed 5 October 2014]
28. Govender S, Otwombe K, Essien T, et al. CD4 counts and viral loads of newly diagnosed HIV infected individuals: implications for treatment as prevention. PLoS One 2014; 9:e90754.
29. Brown AE, Nardone A, Delpech VC. WHO 'treatment as prevention' guidelines are unlikely to decrease HIV transmission in the UK unless undiagnosed HIV infections are reduced. AIDS 2014; 28:281-283.
30. Gardner EM, McLees MP, Steiner JF, et al. The spectrum of engagement in HIV care and its relevance to test-and-treat strategies for prevention of HIV infection. Clin Infect Dis 2011; 52:793-800.
31. Ananworanich J, Schuetz A, Vandergeeten C, et al. Impact of multitargeted antiretroviral treatment on gut T cell depletion and HIV reservoir seeding during acute HIV infection. PLoS One 2012; 7:e33948.
32. WHO. Guidance on couples HIV testing and counselling - including anti-retroviral therapy for treatment and prevention in serodiscordant couples. Geneva, Switzerland: World Health Organization; 2012. http://www.who.int/hiv/pub/guidelines/9789241501972/en/. [Accessed 5 October 2014].
33. Medley A, Baggaley R, Bachanas P, et al. Maximizing the impact of HIV prevention efforts: interventions for couples. AIDS Care 2013; 25:1569-1580.
34. Fenton KA, Aquino GA, Dean HD. Program collaboration and service integration in the prevention and control of HIV infection, viral hepatitis, STDs, and tuberculosis in the U.S.: lessons learned from the field. Public Health Rep 2014; 129 (Suppl 1):1-4.
35. Johnson AS, Hall HI, Hu X, et al. Trends in diagnoses of HIV infection in the United States 2002-2011. JAMA 2014; 312:432-434.
36. Baggaley R, Hensen B, Ajose O, et al. From caution to urgency: the evolution of HIV testing and counselling in Africa. Bull World Health Organ 2012; 90:652-658B.
37. Kennedy CE, Fonner VA, Sweat MD, et al. Provider-initiated HIV testing and counseling in low- and middle-income countries: a systematic review. AIDS Behav 2013; 17:1571-1590.
38. Cohen MS, Chen YQ, McCauley M, et al. Prevention of HIV-1 infection with early antiretroviral therapy. N Engl J Med 2011; 365:493-505.
39. Tanser F, Barnighausen T, Grapsa E, et al. High coverage of ART associated with decline in risk of HIV acquisition in rural KwaZulu-Natal, South Africa. Science 2013; 339:966-971.
40. Granich R, Crowley S, Vitoria M, et al. Highly active antiretroviral treatment for the prevention of HIV transmission. J Int AIDS Soc 2010; 13:1.
41. Granich R, Kahn JG, Bennett R, et al. Expanding ART for treatment and prevention of HIV in South Africa: estimated cost and cost-effectiveness. PLoS One 2012; 7:e30216.
42. Zhang L, Gray RT, Wilson DP. Modelling the epidemiological impact of scaling up HIV testing and antiretroviral treatment in China. Sex Health 2012; 9:261-271.
43. Thailand Ministry of Public Health. AIDS data hub; 2014. http://www.aidsdatahub.org/sites/default/files/publication/Thailand-Ending-AIDS-2013fin.pdf. [Accessed 4 August 2014].
44. Maman S, van Rooyen H, Stankard P, et al. NIMH Project Accept (HPTN 043): results from in-depth interviews with a longitudinal cohort of community members. PLoS One 2014; 9:e87091.
45. WHO. March 2014 supplement to the 2013 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. Geneva, Switzerland: World Health Organization; 2014. http://www.who.int/hiv/pub/guidelines/arv2013/arvs2013upplement-march2014/en/. [Accessed 5 October 2014.]
46. Kawichai S, Celentano D, Srithanaviboonchai K, et al. NIMH Project Accept (HPTN 043) HIV/AIDS community mobilization (CM) to promote mobile HIV voluntary counseling and testing (MVCT) in rural communities in Northern Thailand: modifications by experience. AIDS Behav 2012; 16:1227-1237.
47. Yang M, Prestage G, Maycock B, et al. The acceptability of different HIV testing approaches: cross-sectional study among GMSM in Australia. Sex Transm Infect 2014. [Epub ahead of print]
48. Bigogo G, Amolloh M, Laserson KF, et al. The impact of home-based HIV counseling and testing on care-seeking and incidence of common infectious disease syndromes in rural western Kenya. BMC Infect Dis 2014; 14:376.
49. Krajden M, Cook D, Mak A, et al. Pooled nucleic acid testing increases the diagnostic yield of acute HIV infections in a high-risk population compared to 3rd and 4th generation HIV enzyme immunoassays. J Clin Virol 2014; 61:132-137.
50. Ananworanich J, Phanuphak N, de Souza M, et al. Incidence and characterization of acute HIV-1 infection in a high-risk Thai population. J Acquir Immune Defic Syndr 2008; 49:151-155.
51. Maek ANW, Phanuphak N, Teeratakulpisarn N, et al. Attitudes toward, and interest in, the test-and-treat strategy for HIV prevention among Thai men who have sex with men. AIDS Care 2014; 26:1298-1302.
52. Kredo T, Adeniyi FB, Bateganya M, Pienaar ED. Task shifting from doctors to nondoctors for initiation and maintenance of antiretroviral therapy. Cochrane Database Syst Rev 2014; 7:CD007331.
53. Yan H, Zhang M, Zhao J, et al. The increased effectiveness of HIV preventive intervention among men who have sex with men and of follow-up care for people living with HIV after 'task-shifting' to community-based organizations: a 'cash on service delivery' model in China. PLoS One 2014; 9:e103146.
54. Cohen MS, Dye C, Fraser C, et al. HIV treatment as prevention: debate and commentary-will early infection compromise treatment-as-prevention strategies? PLoS Med 2012; 9:e1001232.
55. Korean Society for AIDS. The 2013 clinical guidelines for the diagnosis and treatment of HIV/AIDS in HIV-infected Koreans. Infect Chemother 2013; 45:455-461.